IWM vs. SBIO

Last updated Jun 9, 2026

IWM (iShares Russell 2000 ETF) and SBIO (ALPS Medical Breakthroughs ETF) are both exchange-traded funds - IWM is a Small Cap Blend Equities fund tracking the Russell 2000 Index, while SBIO is a Health & Biotech Equities fund tracking the S-Network Medical Breakthroughs Index. Both are passively managed. Over the past 10 years, IWM returned 10.78%/yr vs 8.36%/yr for SBIO. A 0.68 correlation means they provide meaningful diversification when combined. IWM charges 0.19%/yr vs 0.50%/yr for SBIO.

Performance

IWM vs. SBIO - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in iShares Russell 2000 ETF (IWM) and ALPS Medical Breakthroughs ETF (SBIO). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, IWM achieves a 15.62% return, which is significantly higher than SBIO's -1.72% return. Over the past 10 years, IWM has outperformed SBIO with an annualized return of 10.78%, while SBIO has yielded a comparatively lower 8.36% annualized return.

IWM

• 1D: 0.87%
• 1M: -0.02%
• YTD: 15.62%
• 6M: 13.83%
• 1Y: 35.52%
• 3Y*: 16.64%
• 5Y*: 5.48%
• 10Y*: 10.78%

SBIO

• 1D: -0.36%
• 1M: -9.33%
• YTD: -1.72%
• 6M: -2.48%
• 1Y: 59.38%
• 3Y*: 16.69%
• 5Y*: 1.33%
• 10Y*: 8.36%

*Multi-year figures are annualized to reflect compound growth (CAGR)

IWM vs. SBIO - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
IWM iShares Russell 2000 ETF	15.62%	12.66%	11.38%	16.83%	-20.48%	14.54%	20.03%	25.39%	-11.12%	14.58%
SBIO ALPS Medical Breakthroughs ETF	-1.72%	55.07%	3.81%	8.68%	-28.08%	-17.55%	21.17%	50.30%	-11.81%	45.67%

Correlation

The correlation between IWM and SBIO is 0.58, which is moderate. They share some common price drivers but move independently often enough to provide real diversification benefit when combined.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.58
Correlation (3Y) Calculated over the trailing 3-year period	0.67
Correlation (5Y) Calculated over the trailing 5-year period	0.69
Correlation (10Y) Calculated over the trailing 10-year period	0.68
Correlation (All Time) Calculated using the full available price history since Jan 2, 2015	0.68

The correlation between IWM and SBIO shifts across timeframes, from 0.58 (1 year) to 0.69 (5 years), reflecting how their relationship changes across market environments.

IWM vs. SBIO - Sectors Allocation Comparison

Sectors	IWM	SBIO
Technology	19.5%	-
Industrials	17.2%	-
Healthcare	16.1%	100.0%
Financial Services	15.6%	-0.0%
Consumer Cyclical	7.9%	-
Energy	5.8%	-
Real Estate	5.6%	-
Basic Materials	4.5%	-
Utilities	3.0%	-
Consumer Defensive	2.1%	-
Communication Services	2.1%	-

Return for Risk

IWM vs. SBIO — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

IWM

IWM Risk / Return Rank: 63
IWM Sharpe Ratio Rank: 61
IWM Sortino Ratio Rank: 60
IWM Omega Ratio Rank: 54
IWM Calmar Ratio Rank: 71
IWM Martin Ratio Rank: 68

SBIO

SBIO Risk / Return Rank: 73
SBIO Sharpe Ratio Rank: 69
SBIO Sortino Ratio Rank: 70
SBIO Omega Ratio Rank: 60
SBIO Calmar Ratio Rank: 88
SBIO Martin Ratio Rank: 78

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

IWM vs. SBIO - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for iShares Russell 2000 ETF (IWM) and ALPS Medical Breakthroughs ETF (SBIO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	IWM	SBIO	Difference
Sharpe ratio: Return per unit of total volatility	1.83	2.02	-0.19
Sortino ratio: Return per unit of downside risk	2.54	2.85	-0.30
Omega ratio: Gain probability vs. loss probability	1.30	1.33	-0.03
Calmar ratio: Return relative to maximum drawdown	3.24	4.72	-1.48
Martin ratio: Return relative to average drawdown	11.44	13.54	-2.10
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

IWM vs. SBIO - Sharpe Ratio Comparison

The current IWM Sharpe Ratio is 1.83, which is comparable to the SBIO Sharpe Ratio of 2.02. The chart below compares the historical Sharpe Ratios of IWM and SBIO, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	IWM	SBIO	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.83	2.02	-0.19
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.24	0.04	+0.20
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.47	0.25	+0.22
Sharpe Ratio (All Time) Calculated using the full available price history	0.36	0.21	+0.15

Drawdowns

IWM vs. SBIO - Drawdown Comparison

The maximum IWM drawdown since its inception was -59.05%, smaller than the maximum SBIO drawdown of -63.06%. Use the drawdown chart below to compare losses from any high point for IWM and SBIO.

Drawdown Indicators

	IWM	SBIO	Difference
Max Drawdown Largest peak-to-trough decline	-59.05%	-63.06%	+4.01%
Max Drawdown (1Y) Largest decline over 1 year	-11.03%	-12.66%	+1.63%
Max Drawdown (3Y) Largest decline over 3 years	-27.50%	-42.44%	+14.94%
Max Drawdown (5Y) Largest decline over 5 years	-31.91%	-53.10%	+21.19%
Max Drawdown (10Y) Largest decline over 10 years	-41.13%	-63.06%	+21.93%
Current Drawdown Current decline from peak	-2.71%	-17.90%	+15.19%
Average Drawdown Average peak-to-trough decline	-10.76%	-28.43%	+17.67%
Ulcer Index Depth and duration of drawdowns from previous peaks	3.11%	4.40%	-1.29%

Volatility

IWM vs. SBIO - Volatility Comparison

The current volatility for iShares Russell 2000 ETF (IWM) is 6.52%, while ALPS Medical Breakthroughs ETF (SBIO) has a volatility of 9.87%. This indicates that IWM experiences smaller price fluctuations and is considered to be less risky than SBIO based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	IWM	SBIO	Difference
Volatility (1M) Calculated over the trailing 1-month period	6.52%	9.87%	-3.35%
Volatility (6M) Calculated over the trailing 6-month period	14.00%	22.68%	-8.68%
Volatility (1Y) Calculated over the trailing 1-year period	19.53%	29.62%	-10.09%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	22.58%	33.56%	-10.98%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	23.07%	33.18%	-10.11%

IWM vs. SBIO - Expense Ratio Comparison

IWM has a 0.19% expense ratio, which is lower than SBIO's 0.50% expense ratio.

Dividends

IWM vs. SBIO - Dividend Comparison

IWM's dividend yield for the trailing twelve months is around 0.89%, while SBIO has not paid dividends to shareholders.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
IWM iShares Russell 2000 ETF	0.89%	1.04%	1.15%	1.35%	1.48%	0.94%	1.04%	1.26%	1.40%	1.26%	1.38%	1.54%
SBIO ALPS Medical Breakthroughs ETF	0.00%	0.00%	3.55%	0.22%	0.00%	0.00%	0.00%	0.04%	2.79%	1.77%	0.00%	0.00%

Frequently Asked Questions

Can I hold both IWM and SBIO in my portfolio?

IWM and SBIO have a correlation of 0.58, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, IWM or SBIO?

SBIO has higher volatility (9.87%) compared to IWM (6.52%). In terms of maximum drawdown, IWM dropped -59.05% vs SBIO's -63.06%.

Which ETF is better, IWM or SBIO?

On 10-year performance, IWM leads with 10.78% vs 8.36% for SBIO. On fees, IWM is cheaper at 0.19% per year. On volatility, IWM has been the lower-risk option at 6.52%. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF has performed better, IWM or SBIO?

Over the 10-year period, IWM has performed better with a 10.78% return vs 8.36%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.

Which ETF is cheaper, IWM or SBIO?

IWM is cheaper with a 0.19% expense ratio, compared with 0.50% for SBIO.

Which ETF pays a higher dividend yield, IWM or SBIO?

IWM has the higher dividend yield at 0.89%, compared with 0.00% for SBIO.

What is the main difference between IWM and SBIO?

IWM is categorized as Small Cap Blend Equities, while SBIO is Health & Biotech Equities. IWM tracks Russell 2000 Index, while SBIO tracks S-Network Medical Breakthroughs Index. They also come from different issuers: iShares and SS&C. Their fees differ too: 0.19% for IWM and 0.50% for SBIO.

Which has better risk-adjusted returns?

SBIO currently has the higher Sharpe Ratio (2.02 vs 1.83), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.