IDNA vs. GERM

Last updated Jun 3, 2026

IDNA (iShares Genomics Immunology and Healthcare ETF Genomics Immunology and Healthcare Fund) and GERM (Amplify Treatments, Testing and Advancements ETF) are both Health & Biotech Equities funds - IDNA tracks the NYSE FactSet Global Genomics and Immuno Biopharma Index while GERM tracks the Prime Treatments, Testing and Advancements Index. Both are passively managed. Over the past year, IDNA returned 41.74% vs 0.00% for GERM. IDNA charges 0.47%/yr vs 0.68%/yr for GERM.

Performance

IDNA vs. GERM - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in iShares Genomics Immunology and Healthcare ETF Genomics Immunology and Healthcare Fund (IDNA) and Amplify Treatments, Testing and Advancements ETF (GERM). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

IDNA

• 1D: -2.18%
• 1M: -2.18%
• YTD: 9.51%
• 6M: 10.53%
• 1Y: 41.74%
• 3Y*: 6.48%
• 5Y*: -8.26%
• 10Y*: —

GERM

• 1D: 0.00%
• 1M: 0.00%
• YTD: 0.00%
• 6M: 0.00%
• 1Y: 0.00%
• 3Y*: —
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

IDNA vs. GERM - Yearly Performance Comparison

	2026 (YTD)	2025	2024
IDNA iShares Genomics Immunology and Healthcare ETF Genomics Immunology and Healthcare Fund	9.51%	17.26%	-4.98%
GERM Amplify Treatments, Testing and Advancements ETF	0.00%	0.00%	0.00%

IDNA vs. GERM - Sectors Allocation Comparison

Sectors	IDNA	GERM
Healthcare	97.8%	99.3%
Industrials	0.4%	-
Basic Materials	-	-
Communication Services	-	-
Consumer Cyclical	-	-
Consumer Defensive	-	-
Energy	-	-
Financial Services	-	0.4%
Real Estate	-	-
Technology	-	-
Utilities	-	-

Return for Risk

IDNA vs. GERM — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

IDNA

IDNA Risk / Return Rank: 57
IDNA Sharpe Ratio Rank: 49
IDNA Sortino Ratio Rank: 50
IDNA Omega Ratio Rank: 43
IDNA Calmar Ratio Rank: 79
IDNA Martin Ratio Rank: 64

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

IDNA vs. GERM - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for iShares Genomics Immunology and Healthcare ETF Genomics Immunology and Healthcare Fund (IDNA) and Amplify Treatments, Testing and Advancements ETF (GERM). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	IDNA	GERM	Difference
Sharpe ratio Return per unit of total volatility	1.71	—	—
Sortino ratio Return per unit of downside risk	2.48	—	—
Omega ratio Gain probability vs. loss probability	1.28	—	—
Calmar ratio Return relative to maximum drawdown	4.09	—	—
Martin ratio Return relative to average drawdown	11.79	—	—
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

Sharpe Ratios by Period

	IDNA	GERM	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.71	—	—
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.29	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	0.10	—	—

Drawdowns

IDNA vs. GERM - Drawdown Comparison

The maximum IDNA drawdown since its inception was -68.26%, which is greater than GERM's maximum drawdown of 0.00%. Use the drawdown chart below to compare losses from any high point for IDNA and GERM.

Drawdown Indicators

	IDNA	GERM	Difference
Max Drawdown Largest peak-to-trough decline	-68.26%	0.00%	-68.26%
Max Drawdown (1Y) Largest decline over 1 year	-10.66%	0.00%	-10.66%
Max Drawdown (3Y) Largest decline over 3 years	-29.73%	—	—
Max Drawdown (5Y) Largest decline over 5 years	-68.26%	—	—
Current Drawdown Current decline from peak	-46.01%	0.00%	-46.01%
Average Drawdown Average peak-to-trough decline	-36.24%	0.00%	-36.24%
Ulcer Index Depth and duration of drawdowns from previous peaks	3.70%	0.00%	+3.70%

Volatility

IDNA vs. GERM - Volatility Comparison

iShares Genomics Immunology and Healthcare ETF Genomics Immunology and Healthcare Fund (IDNA) has a higher volatility of 7.24% compared to Amplify Treatments, Testing and Advancements ETF (GERM) at 0.00%. This indicates that IDNA's price experiences larger fluctuations and is considered to be riskier than GERM based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	IDNA	GERM	Difference
Volatility (1M) Calculated over the trailing 1-month period	7.24%	0.00%	+7.24%
Volatility (6M) Calculated over the trailing 6-month period	18.21%	0.00%	+18.21%
Volatility (1Y) Calculated over the trailing 1-year period	24.51%	0.00%	+24.51%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	28.42%	0.00%	+28.42%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	29.53%	0.00%	+29.53%

IDNA vs. GERM - Expense Ratio Comparison

IDNA has a 0.47% expense ratio, which is lower than GERM's 0.68% expense ratio.

Dividends

IDNA vs. GERM - Dividend Comparison

IDNA's dividend yield for the trailing twelve months is around 1.08%, while GERM has not paid dividends to shareholders.

Position	TTM	2025	2024	2023	2022	2021	2020	2019
GERM Amplify Treatments, Testing and Advancements ETF	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
IDNA iShares Genomics Immunology and Healthcare ETF Genomics Immunology and Healthcare Fund	1.08%	1.18%	0.98%	1.04%	0.54%	0.70%	0.26%	0.80%

Frequently Asked Questions

Which is riskier, IDNA or GERM?

IDNA has higher volatility (7.24%) compared to GERM (0.00%). In terms of maximum drawdown, IDNA dropped -68.26% vs GERM's 0.00%.

Which ETF is better, IDNA or GERM?

On 1-year performance, IDNA leads with 41.74% vs 0.00% for GERM. On fees, IDNA is cheaper at 0.47% per year. On volatility, GERM has been the lower-risk option at 0.00%. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF has performed better, IDNA or GERM?

Over the 1-year period, IDNA has performed better with a 41.74% return vs 0.00%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.

Which ETF is cheaper, IDNA or GERM?

IDNA is cheaper with a 0.47% expense ratio, compared with 0.68% for GERM.

Which ETF pays a higher dividend yield, IDNA or GERM?

IDNA has the higher dividend yield at 1.08%, compared with 0.00% for GERM.

What is the main difference between IDNA and GERM?

IDNA tracks NYSE FactSet Global Genomics and Immuno Biopharma Index, while GERM tracks Prime Treatments, Testing and Advancements Index. They also come from different issuers: iShares and Amplify. Their fees differ too: 0.47% for IDNA and 0.68% for GERM.