IDNA vs. PBE
Compare and contrast key facts about iShares Genomics Immunology and Healthcare ETF Genomics Immunology and Healthcare Fund (IDNA) and Invesco Dynamic Biotechnology & Genome ETF (PBE).
IDNA and PBE are both exchange-traded funds (ETFs), meaning they are traded on stock exchanges and can be bought and sold throughout the day. IDNA is a passively managed fund by iShares that tracks the performance of the NYSE FactSet Global Genomics and Immuno Biopharma Index. It was launched on Jun 11, 2019. PBE is a passively managed fund by Invesco that tracks the performance of the Dynamic Biotech & Genome Intellidex Index (AMEX). It was launched on Jun 23, 2005. Both IDNA and PBE are passive ETFs, meaning that they are not actively managed but aim to replicate the performance of the underlying index as closely as possible.
Performance
IDNA vs. PBE - Performance Comparison
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IDNA vs. PBE - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | |
|---|---|---|---|---|---|---|---|---|
IDNA iShares Genomics Immunology and Healthcare ETF Genomics Immunology and Healthcare Fund | 10.92% | 17.26% | -0.72% | -7.63% | -42.28% | -3.98% | 54.30% | 20.83% |
PBE Invesco Dynamic Biotechnology & Genome ETF | -3.51% | 24.84% | 1.10% | 3.71% | -10.83% | 1.54% | 25.66% | 9.60% |
Returns By Period
In the year-to-date period, IDNA achieves a 10.92% return, which is significantly higher than PBE's -3.51% return.
IDNA
- 1D
- 4.46%
- 1M
- -6.68%
- YTD
- 10.92%
- 6M
- 23.74%
- 1Y
- 43.65%
- 3Y*
- 8.86%
- 5Y*
- -8.02%
- 10Y*
- —
PBE
- 1D
- 3.03%
- 1M
- -3.31%
- YTD
- -3.51%
- 6M
- 14.03%
- 1Y
- 26.26%
- 3Y*
- 8.51%
- 5Y*
- 1.51%
- 10Y*
- 7.52%
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IDNA vs. PBE - Expense Ratio Comparison
IDNA has a 0.47% expense ratio, which is lower than PBE's 0.59% expense ratio.
Return for Risk
IDNA vs. PBE — Risk / Return Rank
IDNA
PBE
IDNA vs. PBE - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for iShares Genomics Immunology and Healthcare ETF Genomics Immunology and Healthcare Fund (IDNA) and Invesco Dynamic Biotechnology & Genome ETF (PBE). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| IDNA | PBE | Difference | |
|---|---|---|---|
Sharpe ratioReturn per unit of total volatility | 1.58 | 1.16 | +0.42 |
Sortino ratioReturn per unit of downside risk | 2.21 | 1.73 | +0.48 |
Omega ratioGain probability vs. loss probability | 1.26 | 1.22 | +0.05 |
Calmar ratioReturn relative to maximum drawdown | 3.20 | 2.12 | +1.08 |
Martin ratioReturn relative to average drawdown | 10.48 | 6.21 | +4.28 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| IDNA | PBE | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 1.58 | 1.16 | +0.42 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | -0.28 | 0.07 | -0.35 |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | — | 0.30 | — |
Sharpe Ratio (All Time)Calculated using the full available price history | 0.11 | 0.32 | -0.21 |
Correlation
The correlation between IDNA and PBE is 0.85, which is considered to be high. That indicates a strong positive relationship between their price movements. Having highly-correlated positions in a portfolio may signal a lack of diversification, potentially leading to increased risk during market downturns.
Dividends
IDNA vs. PBE - Dividend Comparison
IDNA's dividend yield for the trailing twelve months is around 1.06%, less than PBE's 1.09% yield.
| TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
IDNA iShares Genomics Immunology and Healthcare ETF Genomics Immunology and Healthcare Fund | 1.06% | 1.18% | 0.98% | 1.04% | 0.54% | 0.70% | 0.26% | 0.80% | 0.00% | 0.00% | 0.00% | 0.00% |
PBE Invesco Dynamic Biotechnology & Genome ETF | 1.09% | 1.00% | 0.05% | 0.02% | 0.00% | 0.00% | 0.04% | 0.00% | 0.00% | 0.57% | 0.38% | 1.12% |
Drawdowns
IDNA vs. PBE - Drawdown Comparison
The maximum IDNA drawdown since its inception was -68.26%, which is greater than PBE's maximum drawdown of -45.69%. Use the drawdown chart below to compare losses from any high point for IDNA and PBE.
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Drawdown Indicators
| IDNA | PBE | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -68.26% | -45.69% | -22.57% |
Max Drawdown (1Y)Largest decline over 1 year | -12.11% | -11.73% | -0.38% |
Max Drawdown (5Y)Largest decline over 5 years | -68.26% | -34.71% | -33.55% |
Max Drawdown (10Y)Largest decline over 10 years | — | -37.84% | — |
Current DrawdownCurrent decline from peak | -45.31% | -7.54% | -37.77% |
Average DrawdownAverage peak-to-trough decline | -36.04% | -16.33% | -19.71% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 3.83% | 4.01% | -0.18% |
Volatility
IDNA vs. PBE - Volatility Comparison
iShares Genomics Immunology and Healthcare ETF Genomics Immunology and Healthcare Fund (IDNA) has a higher volatility of 10.11% compared to Invesco Dynamic Biotechnology & Genome ETF (PBE) at 7.57%. This indicates that IDNA's price experiences larger fluctuations and is considered to be riskier than PBE based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| IDNA | PBE | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 10.11% | 7.57% | +2.54% |
Volatility (6M)Calculated over the trailing 6-month period | 18.36% | 13.75% | +4.61% |
Volatility (1Y)Calculated over the trailing 1-year period | 27.87% | 22.72% | +5.15% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 28.53% | 22.70% | +5.83% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 29.69% | 25.15% | +4.54% |