IAUM vs. SBIO

Last updated Jul 21, 2026

IAUM (iShares Gold Trust Micro) and SBIO (ALPS Medical Breakthroughs ETF) are both exchange-traded funds - IAUM is a Gold fund tracking the LBMA Gold Price PM, while SBIO is a Health & Biotech Equities fund tracking the S-Network Medical Breakthroughs Index. Both are passively managed. Over the past 5 years, IAUM returned 17.21%/yr vs 6.86%/yr for SBIO. At a 0.12 correlation, their price movements are largely independent. IAUM charges 0.09%/yr vs 0.50%/yr for SBIO.

Performance

IAUM vs. SBIO - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in iShares Gold Trust Micro (IAUM) and ALPS Medical Breakthroughs ETF (SBIO). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, IAUM achieves a -7.12% return, which is significantly lower than SBIO's 24.17% return.

IAUM

• 1D: -0.18%
• 1M: -4.97%
• 6M: -12.59%
• YTD: -7.12%
• 1Y: 19.59%
• 3Y*: 26.77%
• 5Y*: 17.21%
• 10Y*: —
• ALL TIME*: 17.56%

SBIO

• 1D: -2.45%
• 1M: 15.41%
• 6M: 24.53%
• YTD: 24.17%
• 1Y: 93.61%
• 3Y*: 27.21%
• 5Y*: 6.86%
• 10Y*: 10.96%
• ALL TIME*: 9.19%

*Multi-year figures are annualized to reflect compound growth (CAGR)

IAUM vs. SBIO - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021
IAUM iShares Gold Trust Micro	-7.12%	64.27%	27.04%	13.12%	-0.49%	3.87%
SBIO ALPS Medical Breakthroughs ETF	24.17%	55.07%	3.81%	8.68%	-28.08%	-14.92%

Correlation

The correlation between IAUM and SBIO is 0.20, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.20
Correlation (3Y) Calculated over the trailing 3-year period	0.16
Correlation (5Y) Calculated over the trailing 5-year period	0.12
Correlation (All Time) Calculated using the full available price history since Jun 29, 2021	0.12

Return for Risk

IAUM vs. SBIO — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

IAUM

IAUM Risk / Return Rank: 24
IAUM Sharpe Ratio Rank: 26
IAUM Sortino Ratio Rank: 24
IAUM Omega Ratio Rank: 28
IAUM Calmar Ratio Rank: 22
IAUM Martin Ratio Rank: 21

SBIO

SBIO Risk / Return Rank: 95
SBIO Sharpe Ratio Rank: 96
SBIO Sortino Ratio Rank: 94
SBIO Omega Ratio Rank: 91
SBIO Calmar Ratio Rank: 97
SBIO Martin Ratio Rank: 95

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

IAUM vs. SBIO - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for iShares Gold Trust Micro (IAUM) and ALPS Medical Breakthroughs ETF (SBIO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	IAUM	SBIO	Difference
Sharpe ratio: Return per unit of total volatility	0.71	3.07	-2.36
Sortino ratio: Return per unit of downside risk	1.05	3.87	-2.82
Omega ratio: Gain probability vs. loss probability	1.15	1.46	-0.31
Calmar ratio: Return relative to maximum drawdown	0.75	7.44	-6.69
Martin ratio: Return relative to average drawdown	1.75	20.36	-18.61

IAUM vs. SBIO - Sharpe Ratio Comparison

The current IAUM Sharpe Ratio is 0.71, which is lower than the SBIO Sharpe Ratio of 3.07. The chart below compares the historical Sharpe Ratios of IAUM and SBIO, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

IAUM vs. SBIO - Drawdown Comparison

The maximum IAUM drawdown since its inception was -26.31%, smaller than the maximum SBIO drawdown of -63.06%. Use the drawdown chart below to compare losses from any high point for IAUM and SBIO.

Drawdown Indicators

	IAUM	SBIO	Difference
Max Drawdown Largest peak-to-trough decline	-26.31%	-63.06%	+36.75%
Max Drawdown (1Y) Largest decline over 1 year	-26.31%	-12.66%	-13.65%
Max Drawdown (3Y) Largest decline over 3 years	-26.31%	-42.44%	+16.13%
Max Drawdown (5Y) Largest decline over 5 years	-26.31%	-52.49%	+26.18%
Max Drawdown (10Y) Largest decline over 10 years	—	-63.06%	—
Current Drawdown Current decline from peak	-25.77%	-7.75%	-18.02%
Average Drawdown Average peak-to-trough decline	-5.74%	-28.20%	+22.46%
Ulcer Index Depth and duration of drawdowns from previous peaks	11.24%	4.61%	+6.63%

Volatility

IAUM vs. SBIO - Volatility Comparison

The current volatility for iShares Gold Trust Micro (IAUM) is 6.30%, while ALPS Medical Breakthroughs ETF (SBIO) has a volatility of 11.36%. This indicates that IAUM experiences smaller price fluctuations and is considered to be less risky than SBIO based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	IAUM	SBIO	Difference
Volatility (1M) Calculated over the trailing 1-month period	6.30%	11.36%	-5.06%
Volatility (6M) Calculated over the trailing 6-month period	23.90%	24.09%	-0.19%
Volatility (1Y) Calculated over the trailing 1-year period	27.75%	30.73%	-2.98%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	18.26%	33.90%	-15.64%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	18.17%	33.16%	-14.99%

IAUM vs. SBIO - Expense Ratio Comparison

IAUM has a 0.09% expense ratio, which is lower than SBIO's 0.50% expense ratio.

Dividends

IAUM vs. SBIO - Dividend Comparison

Neither IAUM nor SBIO has paid dividends to shareholders.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017
IAUM iShares Gold Trust Micro	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
SBIO ALPS Medical Breakthroughs ETF	0.00%	0.00%	3.55%	0.22%	0.00%	0.00%	0.00%	0.04%	2.79%	1.77%

Frequently Asked Questions

Can I hold both IAUM and SBIO in my portfolio?

IAUM and SBIO have a correlation of 0.20, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, IAUM or SBIO?

SBIO has higher volatility (11.36%) compared to IAUM (6.30%). In terms of maximum drawdown, IAUM dropped -26.31% vs SBIO's -63.06%.

Which ETF is better, IAUM or SBIO?

On 5-year performance, IAUM leads with 17.21% vs 6.86% for SBIO. On fees, IAUM is cheaper at 0.09% per year. On volatility, IAUM has been the lower-risk option at 6.30%. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF has performed better, IAUM or SBIO?

Over the 5-year period, IAUM has performed better with a 17.21% return vs 6.86%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.

Which ETF is cheaper, IAUM or SBIO?

IAUM is cheaper with a 0.09% expense ratio, compared with 0.50% for SBIO.

Which ETF pays a higher dividend yield, IAUM or SBIO?

IAUM and SBIO have nearly identical dividend yields, around 0.00%.

What is the main difference between IAUM and SBIO?

IAUM is categorized as Gold, while SBIO is Health & Biotech Equities. IAUM tracks LBMA Gold Price PM, while SBIO tracks S-Network Medical Breakthroughs Index. They also come from different issuers: iShares and SS&C. Their fees differ too: 0.09% for IAUM and 0.50% for SBIO.

Which has better risk-adjusted returns?

SBIO currently has the higher Sharpe Ratio (3.07 vs 0.71), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.