GPCR vs. VKTX

Last updated Apr 1, 2026

Compare and contrast key facts about Structure Therapeutics Inc. American Depositary Shares (GPCR) and Viking Therapeutics, Inc. (VKTX).

Performance

GPCR vs. VKTX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Structure Therapeutics Inc. American Depositary Shares (GPCR) and Viking Therapeutics, Inc. (VKTX). The values are adjusted to include any dividend payments, if applicable.

GPCR vs. VKTX - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023
GPCR Structure Therapeutics Inc. American Depositary Shares	-30.70%	156.45%	-33.46%	56.77%
VKTX Viking Therapeutics, Inc.	-7.50%	-12.57%	116.23%	104.51%

Fundamentals

EPS GPCR : -$3.62 VKTX : -$3.19
Total Revenue (TTM) GPCR : $0.00 VKTX : $0.00
Gross Profit (TTM) GPCR : $0.00 VKTX : -$208.00K
EBITDA (TTM) GPCR : -$238.30M VKTX : -$393.01M

Returns By Period

In the year-to-date period, GPCR achieves a -30.70% return, which is significantly lower than VKTX's -7.50% return.

GPCR

• 1D: 9.70%
• 1M: -23.47%
• YTD: -30.70%
• 6M: 72.14%
• 1Y: 178.45%
• 3Y*: 26.54%
• 5Y*: —
• 10Y*: —

VKTX

• 1D: 8.76%
• 1M: -3.84%
• YTD: -7.50%
• 6M: 23.82%
• 1Y: 34.74%
• 3Y*: 25.03%
• 5Y*: 38.96%
• 10Y*: 36.40%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

GPCR vs. VKTX — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

GPCR

GPCR Risk / Return Rank: 87
GPCR Sharpe Ratio Rank: 83
GPCR Sortino Ratio Rank: 96
GPCR Omega Ratio Rank: 92
GPCR Calmar Ratio Rank: 84
GPCR Martin Ratio Rank: 81

VKTX

VKTX Risk / Return Rank: 59
VKTX Sharpe Ratio Rank: 58
VKTX Sortino Ratio Rank: 59
VKTX Omega Ratio Rank: 63
VKTX Calmar Ratio Rank: 56
VKTX Martin Ratio Rank: 57

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

GPCR vs. VKTX - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Structure Therapeutics Inc. American Depositary Shares (GPCR) and Viking Therapeutics, Inc. (VKTX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	GPCR	VKTX	Difference
Sharpe ratio Return per unit of total volatility	1.46	0.44	+1.02
Sortino ratio Return per unit of downside risk	3.85	1.10	+2.75
Omega ratio Gain probability vs. loss probability	1.43	1.17	+0.26
Calmar ratio Return relative to maximum drawdown	2.71	0.60	+2.11
Martin ratio Return relative to average drawdown	6.51	1.32	+5.19
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

GPCR vs. VKTX - Sharpe Ratio Comparison

The current GPCR Sharpe Ratio is 1.46, which is higher than the VKTX Sharpe Ratio of 0.44. The chart below compares the historical Sharpe Ratios of GPCR and VKTX, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	GPCR	VKTX	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.46	0.44	+1.02
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	—	0.39	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	0.37	—
Sharpe Ratio (All Time) Calculated using the full available price history	0.22	0.12	+0.09

Correlation

The correlation between GPCR and VKTX is 0.31, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

GPCR vs. VKTX - Dividend Comparison

Neither GPCR nor VKTX has paid dividends to shareholders.

Tickers have no history of dividend payments

Drawdowns

GPCR vs. VKTX - Drawdown Comparison

The maximum GPCR drawdown since its inception was -80.96%, smaller than the maximum VKTX drawdown of -90.41%. Use the drawdown chart below to compare losses from any high point for GPCR and VKTX.

Drawdown Indicators

	GPCR	VKTX	Difference
Max Drawdown Largest peak-to-trough decline	-80.96%	-90.41%	+9.45%
Max Drawdown (1Y) Largest decline over 1 year	-53.15%	-45.14%	-8.01%
Max Drawdown (5Y) Largest decline over 5 years	—	-78.86%	—
Max Drawdown (10Y) Largest decline over 10 years	—	-89.26%	—
Current Drawdown Current decline from peak	-48.61%	-65.57%	+16.96%
Average Drawdown Average peak-to-trough decline	-41.38%	-59.92%	+18.54%
Ulcer Index Depth and duration of drawdowns from previous peaks	22.10%	20.31%	+1.79%

Volatility

GPCR vs. VKTX - Volatility Comparison

Structure Therapeutics Inc. American Depositary Shares (GPCR) and Viking Therapeutics, Inc. (VKTX) have volatilities of 18.47% and 18.20%, respectively, indicating that both stocks experience similar levels of price fluctuations. This suggests that the risk associated with both stocks, as measured by volatility, is nearly the same. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	GPCR	VKTX	Difference
Volatility (1M) Calculated over the trailing 1-month period	18.47%	18.20%	+0.27%
Volatility (6M) Calculated over the trailing 6-month period	84.72%	45.65%	+39.07%
Volatility (1Y) Calculated over the trailing 1-year period	123.40%	78.68%	+44.72%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	101.04%	101.68%	-0.64%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	101.04%	99.00%	+2.04%

Financials