- Sector
- Healthcare
- Industry
- Biotechnology
- IPO Date
- Feb 3, 2023
Highlights
- Market Cap
- $3.30B
- Enterprise Value
- $2.99B
- EPS (TTM)
- -$2.75
- EBITDA (TTM)
- -$191.27M
- Year Range
- $15.80 - $94.90
- Target Price
- $114.75
- ROA (TTM)
- -11.29%
- ROE (TTM)
- -11.77%
Share Price Chart
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Performance
GPCR Performance Chart
Structure Therapeutics Inc. American Depositary Shares (GPCR) is down 34.6% since the beginning of the year. At $46 per share, GPCR is trading 52.0% below its 52-week high of $95.
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Returns By Period
Structure Therapeutics Inc. American Depositary Shares (GPCR) has returned -34.57% so far this year and 109.43% over the past 12 months.
Structure Therapeutics Inc. American Depositary Shares
- 1D
- 2.25%
- 1M
- 16.13%
- YTD
- -34.57%
- 6M
- -28.05%
- 1Y
- 109.43%
- 3Y*
- 15.78%
- 5Y*
- —
- 10Y*
- —
Benchmark (S&P 500 Index)
- 1D
- -0.37%
- 1M
- -0.01%
- YTD
- 9.16%
- 6M
- 8.64%
- 1Y
- 25.22%
- 3Y*
- 19.78%
- 5Y*
- 11.99%
- 10Y*
- 13.88%
GPCR Monthly Returns History
Based on dividend-adjusted daily data since Feb 3, 2023, GPCR's average daily return is +0.24%, while the average monthly return is +4.66%. At this rate, an investment would double in approximately 1.3 years.
Historically, 49% of months were positive and 51% were negative. The best month was Dec 2025 with a return of +94.2%, while the worst month was Feb 2026 at -28.8%. The longest winning streak lasted 6 consecutive months, and the longest losing streak was 4 months.
On a daily basis, GPCR closed higher 48% of trading days. The best single day was Dec 8, 2025 with a return of +102.5%, while the worst single day was Dec 18, 2023 at -42.8%.
| Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec | Total | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026 | 27.17% | -28.80% | -23.47% | -14.00% | -5.09% | 15.68% | -34.57% | ||||||
| 2025 | 10.51% | -20.75% | -27.12% | 55.98% | -19.41% | -4.69% | -14.18% | 8.43% | 45.08% | 19.00% | 7.47% | 94.22% | 156.45% |
| 2024 | 7.02% | -6.99% | 5.64% | -7.98% | -13.29% | 14.82% | -4.79% | 1.98% | 15.11% | -6.24% | -19.44% | -18.19% | -33.46% |
| 2023 | 2.24% | -6.92% | 6.89% | 25.84% | 29.91% | -11.40% | -23.46% | 78.86% | 47.36% | -25.05% | -26.81% | 63.04% |
Benchmark Metrics
Structure Therapeutics Inc. American Depositary Shares has an annualized alpha of 55.00%, beta of 0.87, and R2 of 0.02 versus S&P 500 Index. Calculated based on daily prices since February 03, 2023.
- This stock captured 10.81% of S&P 500 Index gains and tended to rise during its downturns (downside capture of -181.64%) - a profile typical of hedging or uncorrelated assets.
- R2 of 0.02 means this stock moves largely independently of S&P 500 Index - capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.
- Alpha
- 55.00%
- Beta
- 0.87
- R²
- 0.02
- Upside Capture
- 10.81%
- Downside Capture
- -181.64%
Return for Risk
Risk / Return Rank
GPCR ranks 78 for risk / return — better than 78% of stocks on our site. You're getting solid returns for the risk taken. A good sign, especially for investors who want growth without excessive volatility.
Return / Risk — by metrics
The table below present risk-adjusted performance metrics for Structure Therapeutics Inc. American Depositary Shares (GPCR) and compare them to S&P 500 Index.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| GPCR | Benchmark | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -1.11 | ||
| Sortino ratioReturn per unit of downside risk | +0.44 | ||
| Omega ratioGain probability vs. loss probability | 1.35 | 1.37 | -0.02 |
| Calmar ratioReturn relative to maximum drawdown | 1.78 | 2.78 | -1.00 |
| Martin ratioReturn relative to average drawdown | 3.62 | 12.44 | -8.81 |
Dividends
Dividend History
Drawdowns
Drawdowns Chart
The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.
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Worst Drawdowns
The table below displays the maximum drawdowns of the Structure Therapeutics Inc. American Depositary Shares. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.
The maximum drawdown for the Structure Therapeutics Inc. American Depositary Shares was 80.96%, occurring on Apr 8, 2025. Recovery took 192 trading sessions.
The current Structure Therapeutics Inc. American Depositary Shares drawdown is 51.48%.
Related event | Drawdown | Fall | Recovery | Underwater |
|---|---|---|---|---|
2025 selloff2025 | -80.96%Apr 2025 | 1y 5mo | 9mo 10d | 2y 2moNov 2023 - Jan 2026 |
2026 bear market2026 | -61.74%May 2026 | 3mo 27d | — | 5mo 2dJan 2026 - now |
2023 bear market2023 | -36.32%Aug 2023 | 1mo 3d | 1mo 23d | 2mo 26dJul 2023 - Sep 2023 |
2023 bear market2023 | -20.11%Mar 2023 | 22d | 1mo 26d | 2mo 18dMar 2023 - May 2023 |
2023 correction2023 | -17.31%Feb 2023 | 15d | 10d | 25dFeb 2023 - Mar 2023 |
Drawdown Indicators
| GPCR | Benchmark | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -80.96% | -56.78% | -24.18% |
Max Drawdown (1Y)Largest decline over 1 year | -61.74% | -9.10% | -52.64% |
Max Drawdown (3Y)Largest decline over 3 years | -80.96% | -18.90% | -62.06% |
Max Drawdown (5Y)Largest decline over 5 years | — | -25.43% | — |
Max Drawdown (10Y)Largest decline over 10 years | — | -33.92% | — |
Current DrawdownCurrent decline from peak | -51.48% | -1.80% | -49.68% |
Average DrawdownAverage peak-to-trough decline | -42.12% | -10.71% | -31.41% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 30.31% | 2.03% | +28.28% |
Volatility
Volatility Chart
The chart below shows the rolling one-month volatility.
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Financials
Financial Performance
The chart below illustrates the trends in the financial health of Structure Therapeutics Inc. American Depositary Shares over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.
Valuation
The Valuation section provides an overview of how Structure Therapeutics Inc. American Depositary Shares is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.
PB Ratio
The chart illustrates the Price-to-Book (P/B) ratio for GPCR in comparison with other companies in the Biotechnology industry. Currently, GPCR has a P/B value of 2.3. This P/B ratio is in line with the industry average, suggesting the stock is valued fairly in relation to its book value.
Income Statement
| TTM | |
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Total Revenue | — |
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Gross Profit | — |
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Income | — |
Income Before Tax | — |
Operating Income | — |
EBITDA | — |
EBIT | — |
Earnings From Continuing Operations | — |
Net Income | — |
Income Tax Expense | — |
Other Non-Operating Income (Expenses) | — |
Extraordinary Items | — |
Discontinued Operations | — |
Effect Of Accounting Charges | — |
Non Recurring | — |
Minority Interest | — |
Other Items | — |
Interest Income | — |
Interest Expense | — |
Net Interest Income | — |
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