Structure Therapeutics Inc. American Depositary Shares (GPCR)

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The chart shows the growth of an initial investment of $10,000 in Structure Therapeutics Inc. American Depositary Shares, comparing it to the performance of the S&P 500 index or another benchmark. All prices have been adjusted for splits and dividends.

Structure Therapeutics Inc. American Depositary Shares (GPCR) has returned -30.70% so far this year and 178.45% over the past 12 months.

Based on dividend-adjusted daily data since Feb 3, 2023, GPCR's average daily return is +0.25%, while the average monthly return is +5.02%. At this rate, your investment would double in approximately 1.2 years.

Historically, 47% of months were positive and 53% were negative. The best month was Dec 2025 with a return of +94.2%, while the worst month was Feb 2026 at -28.8%. The longest winning streak lasted 6 consecutive months, and the longest losing streak was 3 months.

On a daily basis, GPCR closed higher 48% of trading days. The best single day was Dec 8, 2025 with a return of +102.5%, while the worst single day was Dec 18, 2023 at -42.8%.

Structure Therapeutics Inc. American Depositary Shares has an annualized alpha of 63.70%, beta of 0.92, and R² of 0.02 versus S&P 500 Index. Calculated based on daily prices since February 06, 2023.

• This stock captured 36.06% of S&P 500 Index gains and tended to rise during its downturns (downside capture of -110.19%) — a profile typical of hedging or uncorrelated assets.
• R² of 0.02 means this stock moves largely independently of S&P 500 Index — capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.

GPCR ranks 87 for risk / return — in the top 87% of stocks on our site. This means strong returns relative to risk — exactly what professional investors look for. Well-suited for investors who want to maximize return per unit of risk.

The table below present risk-adjusted performance metrics for Structure Therapeutics Inc. American Depositary Shares (GPCR) and compare them to a chosen benchmark (S&P 500 Index).

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.

The table below displays the maximum drawdowns of the Structure Therapeutics Inc. American Depositary Shares. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the Structure Therapeutics Inc. American Depositary Shares was 80.96%, occurring on Apr 8, 2025. Recovery took 192 trading sessions.

The current Structure Therapeutics Inc. American Depositary Shares drawdown is 48.61%.

The chart below shows the rolling one-month volatility.

The chart below illustrates the trends in the financial health of Structure Therapeutics Inc. American Depositary Shares over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.

The Valuation section provides an overview of how Structure Therapeutics Inc. American Depositary Shares is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.