GPCR vs. AZN
GPCR (Structure Therapeutics Inc. American Depositary Shares) and AZN (AstraZeneca PLC) are both stocks. Both are in the Healthcare sector — GPCR in Biotechnology, AZN in Drug Manufacturers - General. Over the past 3 years, GPCR returned 9.67%/yr vs 8.37%/yr for AZN. Their 0.13 correlation means their historical movements had little consistent relationship.
Performance
GPCR vs. AZN - Performance Comparison
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Returns By Period
In the year-to-date period, GPCR achieves a -30.93% return, which is significantly lower than AZN's -5.80% return.
GPCR
- 1D
- -2.89%
- 1M
- -10.12%
- 6M
- -45.69%
- YTD
- -30.93%
- 1Y
- 173.11%
- 3Y*
- 9.67%
- 5Y*
- —
- 10Y*
- —
- ALL TIME*
- 20.59%
AZN
- 1D
- -0.99%
- 1M
- -13.07%
- 6M
- -6.66%
- YTD
- -5.80%
- 1Y
- 17.91%
- 3Y*
- 8.37%
- 5Y*
- 10.71%
- 10Y*
- 12.78%
- ALL TIME*
- 12.63%
Liquidity Comparison
| Position | Avg. Volume Value (2W) | Avg. Volume Value (1M) | Avg. Volume Value (3M) |
|---|---|---|---|
| $431.89M | $497.68M | $403.88M | |
| $23.87M | $28.91M | $32.91M |
GPCR vs. AZN - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | |
|---|---|---|---|---|
GPCR Structure Therapeutics Inc. American Depositary Shares | -30.93% | 156.45% | -33.46% | 63.04% |
AZN AstraZeneca PLC | -5.80% | 43.30% | -0.62% | 8.91% |
Correlation
The correlation between GPCR and AZN is 0.24, which is low. Their historical price movements had little consistent relationship.
| Correlation | |
|---|---|
Correlation (1Y) Focuses on recent behavior, but can change the most. | 0.24 |
Correlation (3Y) Balances recent behavior with more history. | 0.13 |
Correlation (All Time) Calculated using the full available price history since Feb 3, 2023 | 0.13 |
The correlation between GPCR and AZN shifts across timeframes, from 0.13 (all time) to 0.24 (1 year), reflecting how their relationship changes across market environments.
Fundamentals
GPCR:
$2.77B
AZN:
$131.47B
GPCR:
-$2.69
AZN:
$13.34
GPCR:
2.40
AZN:
2.63
GPCR:
$0.00
AZN:
$61.18B
GPCR:
$0.00
AZN:
$48.56B
GPCR:
-$191.27M
AZN:
$20.49B
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Return for Risk
GPCR vs. AZN — Risk / Return Rank
GPCR
AZN
GPCR vs. AZN - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Structure Therapeutics Inc. American Depositary Shares (GPCR) and AstraZeneca PLC (AZN). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| GPCR | AZN | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +0.70 | ||
| Sortino ratioReturn per unit of downside risk | +2.60 | ||
| Omega ratioGain probability vs. loss probability | 1.42 | 1.15 | +0.27 |
| Calmar ratioReturn relative to maximum drawdown | 2.77 | 0.92 | +1.85 |
| Martin ratioReturn relative to average drawdown | 5.13 | 2.43 | +2.70 |
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Drawdowns
GPCR vs. AZN - Drawdown Comparison
The maximum GPCR drawdown since its inception was -80.96%, which is greater than AZN's maximum drawdown of -48.94%. Use the drawdown chart below to compare losses from any high point for GPCR and AZN.
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Drawdown Indicators
| GPCR | AZN | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -80.96% | -48.94% | -32.02% |
Max Drawdown (1Y)Largest decline over 1 year | -61.74% | -21.08% | -40.66% |
Max Drawdown (3Y)Largest decline over 3 years | -80.96% | -27.87% | -53.09% |
Max Drawdown (5Y)Largest decline over 5 years | — | -27.87% | — |
Max Drawdown (10Y)Largest decline over 10 years | — | -27.87% | — |
Current DrawdownCurrent decline from peak | -48.78% | -18.62% | -30.16% |
Average DrawdownAverage peak-to-trough decline | -42.26% | -11.39% | -30.87% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 33.24% | 7.99% | +25.25% |
Volatility
GPCR vs. AZN - Volatility Comparison
Structure Therapeutics Inc. American Depositary Shares (GPCR) has a higher volatility of 15.41% compared to AstraZeneca PLC (AZN) at 11.83%. This indicates that GPCR's price experiences larger fluctuations and is considered to be riskier than AZN based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| GPCR | AZN | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 15.41% | 11.83% | +3.58% |
Volatility (6M)Calculated over the trailing 6-month period | 39.45% | 19.94% | +19.51% |
Volatility (1Y)Calculated over the trailing 1-year period | 119.56% | 27.24% | +92.32% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 97.38% | 24.51% | +72.87% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 97.38% | 24.96% | +72.42% |
Dividends
GPCR vs. AZN - Dividend Comparison
GPCR has not paid dividends to shareholders, while AZN's dividend yield for the trailing twelve months is around 3.14%.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
AZN AstraZeneca PLC | 3.14% | 1.70% | 2.27% | 2.15% | 2.12% | 2.35% | 2.80% | 2.81% | 3.69% | 3.95% | 5.01% | 4.06% |
GPCR Structure Therapeutics Inc. American Depositary Shares | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
Financials
GPCR vs. AZN - Financials Comparison
This section allows you to compare key financial metrics between Structure Therapeutics Inc. American Depositary Shares and AstraZeneca PLC. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
Frequently Asked Questions
GPCR and AZN have a correlation of 0.24, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
GPCR has higher volatility (15.41%) compared to AZN (11.83%). In terms of maximum drawdown, GPCR dropped -80.96% vs AZN's -48.94%.
GPCR currently has the higher Sharpe Ratio (1.43 vs 0.73), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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