GNTA vs. NTLA

Last updated Jun 6, 2026

GNTA (Genenta Science S.p.A.) and NTLA (Intellia Therapeutics, Inc.) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. Over the past 3 years, GNTA returned -28.28%/yr vs -32.29%/yr for NTLA. At a 0.06 correlation, their price movements are largely independent.

Performance

GNTA vs. NTLA - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Genenta Science S.p.A. (GNTA) and Intellia Therapeutics, Inc. (NTLA). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, GNTA achieves a 36.91% return, which is significantly lower than NTLA's 50.61% return.

GNTA

• 1D: 4.08%
• 1M: 218.65%
• YTD: 36.91%
• 6M: 9.09%
• 1Y: -49.02%
• 3Y*: -28.28%
• 5Y*: —
• 10Y*: —

NTLA

• 1D: -8.20%
• 1M: -1.24%
• YTD: 50.61%
• 6M: 40.89%
• 1Y: 67.37%
• 3Y*: -32.29%
• 5Y*: -28.46%
• 10Y*: -7.18%

*Multi-year figures are annualized to reflect compound growth (CAGR)

GNTA vs. NTLA - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021
GNTA Genenta Science S.p.A.	36.91%	-65.75%	-12.12%	-10.00%	-49.82%	-0.35%
NTLA Intellia Therapeutics, Inc.	50.61%	-22.90%	-61.76%	-12.61%	-70.49%	-3.32%

Correlation

The correlation between GNTA and NTLA is 0.09, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.09
Correlation (3Y) Calculated over the trailing 3-year period	0.06
Correlation (All Time) Calculated using the full available price history since Dec 16, 2021	0.06

Fundamentals

Market Cap GNTA : $43.29M NTLA : $1.60B
EPS GNTA : -$0.77 NTLA : -$3.58
PB Ratio GNTA : 1.98 NTLA : 2.58
Total Revenue (TTM) GNTA : $0.00 NTLA : $66.09M
Gross Profit (TTM) GNTA : -$14.04K NTLA : -$33.92M
EBITDA (TTM) GNTA : -$16.27M NTLA : -$299.32M

Return for Risk

GNTA vs. NTLA — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

GNTA

GNTA Risk / Return Rank: 31
GNTA Sharpe Ratio Rank: 27
GNTA Sortino Ratio Rank: 41
GNTA Omega Ratio Rank: 42
GNTA Calmar Ratio Rank: 21
GNTA Martin Ratio Rank: 26

NTLA

NTLA Risk / Return Rank: 66
NTLA Sharpe Ratio Rank: 67
NTLA Sortino Ratio Rank: 67
NTLA Omega Ratio Rank: 70
NTLA Calmar Ratio Rank: 64
NTLA Martin Ratio Rank: 59

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

GNTA vs. NTLA - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Genenta Science S.p.A. (GNTA) and Intellia Therapeutics, Inc. (NTLA). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	GNTA	NTLA	Difference
Sharpe ratio: Return per unit of total volatility	-0.33	0.82	-1.15
Sortino ratio: Return per unit of downside risk	0.41	1.59	-1.18
Omega ratio: Gain probability vs. loss probability	1.06	1.23	-0.17
Calmar ratio: Return relative to maximum drawdown	-0.58	1.11	-1.69
Martin ratio: Return relative to average drawdown	-0.83	1.75	-2.57
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

GNTA vs. NTLA - Sharpe Ratio Comparison

The current GNTA Sharpe Ratio is -0.33, which is lower than the NTLA Sharpe Ratio of 0.82. The chart below compares the historical Sharpe Ratios of GNTA and NTLA, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	GNTA	NTLA	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.33	0.82	-1.15
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	—	-0.35	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	-0.09	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.31	-0.06	-0.25

Drawdowns

GNTA vs. NTLA - Drawdown Comparison

The maximum GNTA drawdown since its inception was -95.11%, roughly equal to the maximum NTLA drawdown of -96.45%. Use the drawdown chart below to compare losses from any high point for GNTA and NTLA.

Drawdown Indicators

	GNTA	NTLA	Difference
Max Drawdown Largest peak-to-trough decline	-95.11%	-96.45%	+1.34%
Max Drawdown (1Y) Largest decline over 1 year	-90.65%	-71.27%	-19.38%
Max Drawdown (3Y) Largest decline over 3 years	-91.62%	-86.36%	-5.26%
Max Drawdown (5Y) Largest decline over 5 years	—	-96.45%	—
Max Drawdown (10Y) Largest decline over 10 years	—	-96.45%	—
Current Drawdown Current decline from peak	-82.81%	-92.34%	+9.53%
Average Drawdown Average peak-to-trough decline	-61.00%	-57.06%	-3.94%
Ulcer Index Depth and duration of drawdowns from previous peaks	64.13%	45.14%	+18.99%

Volatility

GNTA vs. NTLA - Volatility Comparison

Genenta Science S.p.A. (GNTA) has a higher volatility of 65.05% compared to Intellia Therapeutics, Inc. (NTLA) at 23.64%. This indicates that GNTA's price experiences larger fluctuations and is considered to be riskier than NTLA based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	GNTA	NTLA	Difference
Volatility (1M) Calculated over the trailing 1-month period	65.05%	23.64%	+41.41%
Volatility (6M) Calculated over the trailing 6-month period	92.19%	54.65%	+37.54%
Volatility (1Y) Calculated over the trailing 1-year period	158.88%	96.55%	+62.33%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	102.35%	80.89%	+21.46%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	102.35%	78.39%	+23.96%

Dividends

GNTA vs. NTLA - Dividend Comparison

Neither GNTA nor NTLA has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both GNTA and NTLA in my portfolio?

GNTA and NTLA have a correlation of 0.09, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, GNTA or NTLA?

GNTA has higher volatility (65.05%) compared to NTLA (23.64%). In terms of maximum drawdown, GNTA dropped -95.11% vs NTLA's -96.45%.

Which has better risk-adjusted returns?

NTLA currently has the higher Sharpe Ratio (0.82 vs -0.33), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.