GNOM vs. VGT

Last updated Jun 26, 2026

GNOM (Global X Genomics & Biotechnology ETF) and VGT (Vanguard Information Technology ETF) are both exchange-traded funds - GNOM is a Health & Biotech Equities fund tracking the Solactive Genomics Index, while VGT is a Technology Equities fund tracking the MSCI USA IMI Information Technology 25/50 Index. Both are passively managed. Over the past 5 years, GNOM returned -10.28%/yr vs 19.42%/yr for VGT. A 0.57 correlation means they provide meaningful diversification when combined. GNOM charges 0.50%/yr vs 0.09%/yr for VGT.

Performance

GNOM vs. VGT - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Global X Genomics & Biotechnology ETF (GNOM) and Vanguard Information Technology ETF (VGT). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, GNOM achieves a 20.90% return, which is significantly lower than VGT's 22.82% return.

GNOM

• 1D: 2.19%
• 1M: 16.88%
• YTD: 20.90%
• 6M: 16.82%
• 1Y: 66.61%
• 3Y*: 4.83%
• 5Y*: -10.28%
• 10Y*: —

VGT

• 1D: 0.30%
• 1M: -2.07%
• YTD: 22.82%
• 6M: 20.81%
• 1Y: 42.45%
• 3Y*: 30.31%
• 5Y*: 19.42%
• 10Y*: 25.77%

*Multi-year figures are annualized to reflect compound growth (CAGR)

GNOM vs. VGT - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019
GNOM Global X Genomics & Biotechnology ETF	20.90%	18.65%	-15.99%	-8.63%	-36.27%	-15.93%	51.52%	2.03%
VGT Vanguard Information Technology ETF	22.82%	21.77%	29.30%	52.66%	-29.70%	30.45%	46.04%	20.31%

Correlation

The correlation between GNOM and VGT is 0.40, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.40
Correlation (3Y) Calculated over the trailing 3-year period	0.46
Correlation (5Y) Calculated over the trailing 5-year period	0.56
Correlation (All Time) Calculated using the full available price history since Apr 10, 2019	0.57

The correlation between GNOM and VGT shifts across timeframes, from 0.40 (1 year) to 0.57 (all time), reflecting how their relationship changes across market environments.

GNOM vs. VGT - Sectors Allocation Comparison

Sectors	GNOM	VGT
Healthcare	99.7%	0.0%
Technology	0.3%	98.5%
Basic Materials	-	0.0%
Communication Services	-	0.5%
Consumer Cyclical	-	0.1%
Consumer Defensive	-	-
Energy	-	0.3%
Financial Services	-	0.5%
Industrials	-	0.4%
Real Estate	-	-
Utilities	-	-

Return for Risk

GNOM vs. VGT — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

GNOM

GNOM Risk / Return Rank: 78
GNOM Sharpe Ratio Rank: 87
GNOM Sortino Ratio Rank: 85
GNOM Omega Ratio Rank: 74
GNOM Calmar Ratio Rank: 80
GNOM Martin Ratio Rank: 67

VGT

VGT Risk / Return Rank: 60
VGT Sharpe Ratio Rank: 67
VGT Sortino Ratio Rank: 59
VGT Omega Ratio Rank: 60
VGT Calmar Ratio Rank: 61
VGT Martin Ratio Rank: 53

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

GNOM vs. VGT - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Global X Genomics & Biotechnology ETF (GNOM) and Vanguard Information Technology ETF (VGT). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	GNOM	VGT	Difference
Sharpe ratio: Return per unit of total volatility	2.44	1.88	+0.56
Sortino ratio: Return per unit of downside risk	3.28	2.41	+0.87
Omega ratio: Gain probability vs. loss probability	1.38	1.32	+0.06
Calmar ratio: Return relative to maximum drawdown	3.68	2.60	+1.08
Martin ratio: Return relative to average drawdown	10.57	7.87	+2.70

GNOM vs. VGT - Sharpe Ratio Comparison

The current GNOM Sharpe Ratio is 2.44, which is comparable to the VGT Sharpe Ratio of 1.88. The chart below compares the historical Sharpe Ratios of GNOM and VGT, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

GNOM vs. VGT - Drawdown Comparison

The maximum GNOM drawdown since its inception was -75.00%, which is greater than VGT's maximum drawdown of -54.63%. Use the drawdown chart below to compare losses from any high point for GNOM and VGT.

Drawdown Indicators

	GNOM	VGT	Difference
Max Drawdown Largest peak-to-trough decline	-75.00%	-54.63%	-20.37%
Max Drawdown (1Y) Largest decline over 1 year	-18.17%	-16.40%	-1.77%
Max Drawdown (3Y) Largest decline over 3 years	-44.24%	-27.23%	-17.01%
Max Drawdown (5Y) Largest decline over 5 years	-72.29%	-35.07%	-37.22%
Max Drawdown (10Y) Largest decline over 10 years	—	-35.07%	—
Current Drawdown Current decline from peak	-50.04%	-8.08%	-41.96%
Average Drawdown Average peak-to-trough decline	-40.64%	-7.95%	-32.69%
Ulcer Index Depth and duration of drawdowns from previous peaks	6.32%	5.41%	+0.91%

Volatility

GNOM vs. VGT - Volatility Comparison

The current volatility for Global X Genomics & Biotechnology ETF (GNOM) is 9.74%, while Vanguard Information Technology ETF (VGT) has a volatility of 11.17%. This indicates that GNOM experiences smaller price fluctuations and is considered to be less risky than VGT based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	GNOM	VGT	Difference
Volatility (1M) Calculated over the trailing 1-month period	9.74%	11.17%	-1.43%
Volatility (6M) Calculated over the trailing 6-month period	20.61%	18.51%	+2.10%
Volatility (1Y) Calculated over the trailing 1-year period	27.40%	22.66%	+4.74%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	33.70%	25.55%	+8.15%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	34.18%	24.76%	+9.42%

GNOM vs. VGT - Expense Ratio Comparison

GNOM has a 0.50% expense ratio, which is higher than VGT's 0.09% expense ratio.

Dividends

GNOM vs. VGT - Dividend Comparison

GNOM's dividend yield for the trailing twelve months is around 1.14%, more than VGT's 0.45% yield.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
GNOM Global X Genomics & Biotechnology ETF	1.14%	1.37%	0.00%	0.00%	0.00%	0.03%	0.14%	0.00%	0.00%	0.00%	0.00%	0.00%
VGT Vanguard Information Technology ETF	0.45%	0.40%	0.60%	0.65%	0.91%	0.64%	0.82%	1.11%	1.29%	0.99%	1.31%	1.28%

Frequently Asked Questions

Can I hold both GNOM and VGT in my portfolio?

GNOM and VGT have a correlation of 0.40, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, GNOM or VGT?

VGT has higher volatility (11.17%) compared to GNOM (9.74%). In terms of maximum drawdown, GNOM dropped -75.00% vs VGT's -54.63%.

Which ETF is better, GNOM or VGT?

On 5-year performance, VGT leads with 19.42% vs -10.28% for GNOM. On fees, VGT is cheaper at 0.09% per year. On volatility, GNOM has been the lower-risk option at 9.74%. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF has performed better, GNOM or VGT?

Over the 5-year period, VGT has performed better with a 19.42% return vs -10.28%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.

Which ETF is cheaper, GNOM or VGT?

VGT is cheaper with a 0.09% expense ratio, compared with 0.50% for GNOM.

Which ETF pays a higher dividend yield, GNOM or VGT?

GNOM has the higher dividend yield at 1.14%, compared with 0.45% for VGT.

What is the main difference between GNOM and VGT?

GNOM is categorized as Health & Biotech Equities, while VGT is Technology Equities. GNOM tracks Solactive Genomics Index, while VGT tracks MSCI USA IMI Information Technology 25/50 Index. They also come from different issuers: Global X and Vanguard. Their fees differ too: 0.50% for GNOM and 0.09% for VGT.

Which has better risk-adjusted returns?

GNOM currently has the higher Sharpe Ratio (2.44 vs 1.88), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.