FPRO vs. FMED

Last updated Apr 1, 2026

Compare and contrast key facts about Fidelity Real Estate Investment ETF (FPRO) and Fidelity Disruptive Medicine ETF (FMED).

FPRO and FMED are both exchange-traded funds (ETFs), meaning they are traded on stock exchanges and can be bought and sold throughout the day. FPRO is an actively managed fund by Fidelity. It was launched on Feb 2, 2021. FMED is an actively managed fund by Fidelity. It was launched on Apr 16, 2020.

Performance

FPRO vs. FMED - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Fidelity Real Estate Investment ETF (FPRO) and Fidelity Disruptive Medicine ETF (FMED). The values are adjusted to include any dividend payments, if applicable.

FPRO vs. FMED - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023
FPRO Fidelity Real Estate Investment ETF	3.28%	2.60%	5.63%	8.67%
FMED Fidelity Disruptive Medicine ETF	-9.18%	9.69%	2.29%	-4.20%

Returns By Period

In the year-to-date period, FPRO achieves a 3.28% return, which is significantly higher than FMED's -9.18% return.

FPRO

• 1D: 1.39%
• 1M: -5.97%
• YTD: 3.28%
• 6M: 2.58%
• 1Y: 2.28%
• 3Y*: 6.41%
• 5Y*: 4.08%
• 10Y*: —

FMED

• 1D: 4.31%
• 1M: -6.27%
• YTD: -9.18%
• 6M: -1.52%
• 1Y: 4.05%
• 3Y*: —
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

FPRO vs. FMED - Expense Ratio Comparison

FPRO has a 0.59% expense ratio, which is higher than FMED's 0.50% expense ratio.

FPRO

Fidelity Real Estate Investment ETF

FMED

Fidelity Disruptive Medicine ETF

Return for Risk

FPRO vs. FMED — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

FPRO

FPRO Risk / Return Rank: 17
FPRO Sharpe Ratio Rank: 16
FPRO Sortino Ratio Rank: 15
FPRO Omega Ratio Rank: 15
FPRO Calmar Ratio Rank: 18
FPRO Martin Ratio Rank: 20

FMED

FMED Risk / Return Rank: 16
FMED Sharpe Ratio Rank: 17
FMED Sortino Ratio Rank: 18
FMED Omega Ratio Rank: 16
FMED Calmar Ratio Rank: 15
FMED Martin Ratio Rank: 15

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

FPRO vs. FMED - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Fidelity Real Estate Investment ETF (FPRO) and Fidelity Disruptive Medicine ETF (FMED). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	FPRO	FMED	Difference
Sharpe ratio Return per unit of total volatility	0.14	0.19	-0.05
Sortino ratio Return per unit of downside risk	0.31	0.43	-0.13
Omega ratio Gain probability vs. loss probability	1.04	1.05	-0.01
Calmar ratio Return relative to maximum drawdown	0.26	0.16	+0.10
Martin ratio Return relative to average drawdown	1.03	0.48	+0.55
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

FPRO vs. FMED - Sharpe Ratio Comparison

The current FPRO Sharpe Ratio is 0.14, which is comparable to the FMED Sharpe Ratio of 0.19. The chart below compares the historical Sharpe Ratios of FPRO and FMED, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	FPRO	FMED	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	0.14	0.19	-0.05
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.22	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	0.29	-0.05	+0.33

Correlation

The correlation between FPRO and FMED is 0.46, which is considered to be moderate. This suggests that the two assets have some degree of positive relationship in their price movements. Moderate correlation can be acceptable for portfolio diversification, offering a balance between risk and potential returns.

Dividends

FPRO vs. FMED - Dividend Comparison

FPRO's dividend yield for the trailing twelve months is around 2.74%, while FMED has not paid dividends to shareholders.

	TTM	2025	2024	2023	2022	2021
FPRO Fidelity Real Estate Investment ETF	2.74%	2.69%	2.50%	2.83%	2.67%	1.69%
FMED Fidelity Disruptive Medicine ETF	0.00%	0.00%	0.46%	0.00%	0.00%	0.00%

Drawdowns

FPRO vs. FMED - Drawdown Comparison

The maximum FPRO drawdown since its inception was -32.81%, which is greater than FMED's maximum drawdown of -21.84%. Use the drawdown chart below to compare losses from any high point for FPRO and FMED.

Drawdown Indicators

	FPRO	FMED	Difference
Max Drawdown Largest peak-to-trough decline	-32.81%	-21.84%	-10.97%
Max Drawdown (1Y) Largest decline over 1 year	-12.51%	-18.33%	+5.82%
Max Drawdown (5Y) Largest decline over 5 years	-32.81%	—	—
Current Drawdown Current decline from peak	-6.90%	-14.81%	+7.91%
Average Drawdown Average peak-to-trough decline	-13.03%	-6.64%	-6.39%
Ulcer Index Depth and duration of drawdowns from previous peaks	3.15%	5.90%	-2.75%

Volatility

FPRO vs. FMED - Volatility Comparison

The current volatility for Fidelity Real Estate Investment ETF (FPRO) is 4.34%, while Fidelity Disruptive Medicine ETF (FMED) has a volatility of 8.24%. This indicates that FPRO experiences smaller price fluctuations and is considered to be less risky than FMED based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	FPRO	FMED	Difference
Volatility (1M) Calculated over the trailing 1-month period	4.34%	8.24%	-3.90%
Volatility (6M) Calculated over the trailing 6-month period	9.25%	13.98%	-4.73%
Volatility (1Y) Calculated over the trailing 1-year period	16.46%	21.35%	-4.89%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	18.64%	18.31%	+0.33%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	18.51%	18.31%	+0.20%