ENGN vs. VUG

Last updated Jun 3, 2026

ENGN (enGene Holdings Inc) is a stock, while VUG (Vanguard Growth ETF) is Large Cap Growth Equities fund tracking the CRSP US Large Cap Growth Index. Over the past year, ENGN returned -56.28% vs 30.39% for VUG. At a 0.16 correlation, their price movements are largely independent.

Performance

ENGN vs. VUG - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in enGene Holdings Inc (ENGN) and Vanguard Growth ETF (VUG). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, ENGN achieves a -80.73% return, which is significantly lower than VUG's 10.86% return.

ENGN

• 1D: -2.25%
• 1M: -76.00%
• YTD: -80.73%
• 6M: -77.86%
• 1Y: -56.28%
• 3Y*: —
• 5Y*: —
• 10Y*: —

VUG

• 1D: -0.28%
• 1M: 7.37%
• YTD: 10.86%
• 6M: 10.14%
• 1Y: 30.39%
• 3Y*: 26.46%
• 5Y*: 15.71%
• 10Y*: 18.40%

*Multi-year figures are annualized to reflect compound growth (CAGR)

ENGN vs. VUG - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023
ENGN enGene Holdings Inc	-80.73%	35.79%	-27.95%	-53.85%
VUG Vanguard Growth ETF	10.86%	19.40%	32.69%	14.66%

Correlation

The correlation between ENGN and VUG is 0.32, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.32
Correlation (All Time) Calculated using the full available price history since Nov 2, 2023	0.16

The correlation between ENGN and VUG shifts across timeframes, from 0.16 (all time) to 0.32 (1 year), reflecting how their relationship changes across market environments.

Return for Risk

ENGN vs. VUG — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

ENGN

ENGN Risk / Return Rank: 25
ENGN Sharpe Ratio Rank: 21
ENGN Sortino Ratio Rank: 40
ENGN Omega Ratio Rank: 44
ENGN Calmar Ratio Rank: 18
ENGN Martin Ratio Rank: 2

VUG

VUG Risk / Return Rank: 49
VUG Sharpe Ratio Rank: 56
VUG Sortino Ratio Rank: 53
VUG Omega Ratio Rank: 54
VUG Calmar Ratio Rank: 38
VUG Martin Ratio Rank: 41

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

ENGN vs. VUG - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for enGene Holdings Inc (ENGN) and Vanguard Growth ETF (VUG). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	ENGN	VUG	Difference
Sharpe ratio Return per unit of total volatility	-0.45	1.93	-2.39
Sortino ratio Return per unit of downside risk	0.44	2.60	-2.16
Omega ratio Gain probability vs. loss probability	1.08	1.34	-0.25
Calmar ratio Return relative to maximum drawdown	-0.62	1.90	-2.52
Martin ratio Return relative to average drawdown	-1.76	6.65	-8.42
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

ENGN vs. VUG - Sharpe Ratio Comparison

The current ENGN Sharpe Ratio is -0.45, which is lower than the VUG Sharpe Ratio of 1.93. The chart below compares the historical Sharpe Ratios of ENGN and VUG, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	ENGN	VUG	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.45	1.93	-2.39
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	—	0.71	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	0.86	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.46	0.62	-1.08

Drawdowns

ENGN vs. VUG - Drawdown Comparison

The maximum ENGN drawdown since its inception was -92.80%, which is greater than VUG's maximum drawdown of -50.68%. Use the drawdown chart below to compare losses from any high point for ENGN and VUG.

Drawdown Indicators

	ENGN	VUG	Difference
Max Drawdown Largest peak-to-trough decline	-92.80%	-50.68%	-42.12%
Max Drawdown (1Y) Largest decline over 1 year	-88.17%	-16.53%	-71.64%
Max Drawdown (3Y) Largest decline over 3 years	—	-22.85%	—
Max Drawdown (5Y) Largest decline over 5 years	—	-35.61%	—
Max Drawdown (10Y) Largest decline over 10 years	—	-35.61%	—
Current Drawdown Current decline from peak	-91.30%	-0.28%	-91.02%
Average Drawdown Average peak-to-trough decline	-60.96%	-7.09%	-53.87%
Ulcer Index Depth and duration of drawdowns from previous peaks	31.00%	4.71%	+26.29%

Volatility

ENGN vs. VUG - Volatility Comparison

enGene Holdings Inc (ENGN) has a higher volatility of 167.94% compared to Vanguard Growth ETF (VUG) at 3.52%. This indicates that ENGN's price experiences larger fluctuations and is considered to be riskier than VUG based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	ENGN	VUG	Difference
Volatility (1M) Calculated over the trailing 1-month period	167.94%	3.52%	+164.42%
Volatility (6M) Calculated over the trailing 6-month period	174.25%	12.05%	+162.20%
Volatility (1Y) Calculated over the trailing 1-year period	124.17%	15.80%	+108.37%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	133.17%	22.22%	+110.95%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	133.17%	21.44%	+111.73%

Dividends

ENGN vs. VUG - Dividend Comparison

ENGN has not paid dividends to shareholders, while VUG's dividend yield for the trailing twelve months is around 0.37%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
ENGN enGene Holdings Inc	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
VUG Vanguard Growth ETF	0.37%	0.41%	0.47%	0.58%	0.70%	0.48%	0.66%	0.95%	1.32%	1.14%	1.39%	1.30%

Frequently Asked Questions

Can I hold both ENGN and VUG in my portfolio?

ENGN and VUG have a correlation of 0.32, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, ENGN or VUG?

ENGN has higher volatility (167.94%) compared to VUG (3.52%). In terms of maximum drawdown, ENGN dropped -92.80% vs VUG's -50.68%.

Which has better risk-adjusted returns?

VUG currently has the higher Sharpe Ratio (1.93 vs -0.45), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.