ENGN vs. VUG

Last updated Apr 1, 2026

Compare and contrast key facts about enGene Holdings Inc (ENGN) and Vanguard Growth ETF (VUG).

VUG is a passively managed fund by Vanguard that tracks the performance of the CRSP US Large Cap Growth Index. It was launched on Nov 13, 2000.

Performance

ENGN vs. VUG - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in enGene Holdings Inc (ENGN) and Vanguard Growth ETF (VUG). The values are adjusted to include any dividend payments, if applicable.

ENGN vs. VUG - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023
ENGN enGene Holdings Inc	-24.58%	35.79%	-27.95%	-53.85%
VUG Vanguard Growth ETF	-10.37%	19.40%	32.69%	14.66%

Returns By Period

In the year-to-date period, ENGN achieves a -24.58% return, which is significantly lower than VUG's -10.37% return.

ENGN

• 1D: 10.19%
• 1M: -32.64%
• YTD: -24.58%
• 6M: -0.29%
• 1Y: 52.01%
• 3Y*: —
• 5Y*: —
• 10Y*: —

VUG

• 1D: 4.00%
• 1M: -5.12%
• YTD: -10.37%
• 6M: -8.73%
• 1Y: 18.30%
• 3Y*: 21.15%
• 5Y*: 11.43%
• 10Y*: 16.03%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

ENGN vs. VUG — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

ENGN

ENGN Risk / Return Rank: 65
ENGN Sharpe Ratio Rank: 61
ENGN Sortino Ratio Rank: 68
ENGN Omega Ratio Rank: 65
ENGN Calmar Ratio Rank: 66
ENGN Martin Ratio Rank: 66

VUG

VUG Risk / Return Rank: 50
VUG Sharpe Ratio Rank: 49
VUG Sortino Ratio Rank: 54
VUG Omega Ratio Rank: 53
VUG Calmar Ratio Rank: 49
VUG Martin Ratio Rank: 45

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

ENGN vs. VUG - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for enGene Holdings Inc (ENGN) and Vanguard Growth ETF (VUG). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	ENGN	VUG	Difference
Sharpe ratio Return per unit of total volatility	0.56	0.81	-0.25
Sortino ratio Return per unit of downside risk	1.52	1.31	+0.21
Omega ratio Gain probability vs. loss probability	1.19	1.18	+0.01
Calmar ratio Return relative to maximum drawdown	1.19	1.11	+0.07
Martin ratio Return relative to average drawdown	2.85	3.96	-1.10
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

ENGN vs. VUG - Sharpe Ratio Comparison

The current ENGN Sharpe Ratio is 0.56, which is lower than the VUG Sharpe Ratio of 0.81. The chart below compares the historical Sharpe Ratios of ENGN and VUG, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	ENGN	VUG	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	0.56	0.81	-0.25
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	—	0.52	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	0.75	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.29	0.57	-0.86

Correlation

The correlation between ENGN and VUG is 0.14, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

ENGN vs. VUG - Dividend Comparison

ENGN has not paid dividends to shareholders, while VUG's dividend yield for the trailing twelve months is around 0.46%.

	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
ENGN enGene Holdings Inc	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
VUG Vanguard Growth ETF	0.46%	0.41%	0.47%	0.58%	0.70%	0.48%	0.66%	0.95%	1.32%	1.14%	1.39%	1.30%

Drawdowns

ENGN vs. VUG - Drawdown Comparison

The maximum ENGN drawdown since its inception was -85.60%, which is greater than VUG's maximum drawdown of -50.68%. Use the drawdown chart below to compare losses from any high point for ENGN and VUG.

Drawdown Indicators

	ENGN	VUG	Difference
Max Drawdown Largest peak-to-trough decline	-85.60%	-50.68%	-34.92%
Max Drawdown (1Y) Largest decline over 1 year	-49.22%	-16.53%	-32.69%
Max Drawdown (5Y) Largest decline over 5 years	—	-35.61%	—
Max Drawdown (10Y) Largest decline over 10 years	—	-35.61%	—
Current Drawdown Current decline from peak	-65.95%	-13.20%	-52.75%
Average Drawdown Average peak-to-trough decline	-60.01%	-7.13%	-52.88%
Ulcer Index Depth and duration of drawdowns from previous peaks	20.47%	4.66%	+15.81%

Volatility

ENGN vs. VUG - Volatility Comparison

enGene Holdings Inc (ENGN) has a higher volatility of 28.43% compared to Vanguard Growth ETF (VUG) at 7.00%. This indicates that ENGN's price experiences larger fluctuations and is considered to be riskier than VUG based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	ENGN	VUG	Difference
Volatility (1M) Calculated over the trailing 1-month period	28.43%	7.00%	+21.43%
Volatility (6M) Calculated over the trailing 6-month period	72.37%	12.65%	+59.72%
Volatility (1Y) Calculated over the trailing 1-year period	92.92%	22.68%	+70.24%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	125.41%	22.23%	+103.18%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	125.41%	21.38%	+104.03%