CURE vs. SPUU

Last updated Apr 2, 2026

Compare and contrast key facts about Direxion Daily Healthcare Bull 3x Shares (CURE) and Direxion Daily S&P 500 Bull 2x Shares (SPUU).

CURE and SPUU are both exchange-traded funds (ETFs), meaning they are traded on stock exchanges and can be bought and sold throughout the day. CURE is a passively managed fund by Direxion that tracks the performance of the Health Care Select Sector Index (300%). It was launched on Jun 15, 2011. SPUU is a passively managed fund by Direxion that tracks the performance of the S&P 500 Index (200%). It was launched on May 28, 2014. Both CURE and SPUU are passive ETFs, meaning that they are not actively managed but aim to replicate the performance of the underlying index as closely as possible.

Performance

CURE vs. SPUU - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Direxion Daily Healthcare Bull 3x Shares (CURE) and Direxion Daily S&P 500 Bull 2x Shares (SPUU). The values are adjusted to include any dividend payments, if applicable.

CURE vs. SPUU - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
CURE Direxion Daily Healthcare Bull 3x Shares	-15.60%	22.55%	-8.47%	-9.40%	-20.51%	88.30%	5.02%	55.66%	2.82%	69.32%
SPUU Direxion Daily S&P 500 Bull 2x Shares	-8.72%	26.55%	44.25%	47.28%	-38.72%	61.27%	21.85%	66.84%	-14.59%	44.33%

Returns By Period

In the year-to-date period, CURE achieves a -15.60% return, which is significantly lower than SPUU's -8.72% return. Over the past 10 years, CURE has underperformed SPUU with an annualized return of 13.60%, while SPUU has yielded a comparatively higher 21.84% annualized return.

CURE

• 1D: 2.50%
• 1M: -19.24%
• YTD: -15.60%
• 6M: 3.42%
• 1Y: -5.59%
• 3Y*: 0.66%
• 5Y*: 3.67%
• 10Y*: 13.60%

SPUU

• 1D: 1.43%
• 1M: -9.19%
• YTD: -8.72%
• 6M: -6.20%
• 1Y: 28.11%
• 3Y*: 29.46%
• 5Y*: 16.19%
• 10Y*: 21.84%

*Multi-year figures are annualized to reflect compound growth (CAGR)

CURE vs. SPUU - Expense Ratio Comparison

CURE has a 1.08% expense ratio, which is higher than SPUU's 0.64% expense ratio.

CURE

Direxion Daily Healthcare Bull 3x Shares

SPUU

Direxion Daily S&P 500 Bull 2x Shares

Return for Risk

CURE vs. SPUU — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

CURE

CURE Risk / Return Rank: 10
CURE Sharpe Ratio Rank: 10
CURE Sortino Ratio Rank: 13
CURE Omega Ratio Rank: 12
CURE Calmar Ratio Rank: 7
CURE Martin Ratio Rank: 7

SPUU

SPUU Risk / Return Rank: 46
SPUU Sharpe Ratio Rank: 40
SPUU Sortino Ratio Rank: 45
SPUU Omega Ratio Rank: 48
SPUU Calmar Ratio Rank: 46
SPUU Martin Ratio Rank: 53

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

CURE vs. SPUU - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Direxion Daily Healthcare Bull 3x Shares (CURE) and Direxion Daily S&P 500 Bull 2x Shares (SPUU). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	CURE	SPUU	Difference
Sharpe ratio Return per unit of total volatility	-0.11	0.78	-0.89
Sortino ratio Return per unit of downside risk	0.22	1.29	-1.08
Omega ratio Gain probability vs. loss probability	1.03	1.19	-0.17
Calmar ratio Return relative to maximum drawdown	-0.32	1.25	-1.57
Martin ratio Return relative to average drawdown	-0.59	5.36	-5.94
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

CURE vs. SPUU - Sharpe Ratio Comparison

The current CURE Sharpe Ratio is -0.11, which is lower than the SPUU Sharpe Ratio of 0.78. The chart below compares the historical Sharpe Ratios of CURE and SPUU, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	CURE	SPUU	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.11	0.78	-0.89
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.08	0.49	-0.40
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.28	0.61	-0.34
Sharpe Ratio (All Time) Calculated using the full available price history	0.47	0.56	-0.09

Correlation

The correlation between CURE and SPUU is 0.68, which is considered to be moderate. This suggests that the two assets have some degree of positive relationship in their price movements. Moderate correlation can be acceptable for portfolio diversification, offering a balance between risk and potential returns.

Dividends

CURE vs. SPUU - Dividend Comparison

CURE's dividend yield for the trailing twelve months is around 1.26%, less than SPUU's 1.76% yield.

	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
CURE Direxion Daily Healthcare Bull 3x Shares	1.26%	1.12%	1.17%	2.02%	0.38%	0.02%	0.17%	0.40%	0.70%	0.18%	0.00%	0.00%
SPUU Direxion Daily S&P 500 Bull 2x Shares	1.76%	1.63%	0.55%	0.83%	0.88%	3.04%	8.03%	1.80%	5.50%	6.96%	8.08%	4.42%

Drawdowns

CURE vs. SPUU - Drawdown Comparison

The maximum CURE drawdown since its inception was -69.19%, which is greater than SPUU's maximum drawdown of -59.35%. Use the drawdown chart below to compare losses from any high point for CURE and SPUU.

Drawdown Indicators

	CURE	SPUU	Difference
Max Drawdown Largest peak-to-trough decline	-69.19%	-59.35%	-9.84%
Max Drawdown (1Y) Largest decline over 1 year	-33.92%	-23.10%	-10.82%
Max Drawdown (5Y) Largest decline over 5 years	-52.23%	-46.59%	-5.64%
Max Drawdown (10Y) Largest decline over 10 years	-69.19%	-59.35%	-9.84%
Current Drawdown Current decline from peak	-33.01%	-12.15%	-20.86%
Average Drawdown Average peak-to-trough decline	-17.95%	-9.62%	-8.33%
Ulcer Index Depth and duration of drawdowns from previous peaks	18.24%	5.41%	+12.83%

Volatility

CURE vs. SPUU - Volatility Comparison

Direxion Daily Healthcare Bull 3x Shares (CURE) has a higher volatility of 14.17% compared to Direxion Daily S&P 500 Bull 2x Shares (SPUU) at 10.73%. This indicates that CURE's price experiences larger fluctuations and is considered to be riskier than SPUU based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	CURE	SPUU	Difference
Volatility (1M) Calculated over the trailing 1-month period	14.17%	10.73%	+3.44%
Volatility (6M) Calculated over the trailing 6-month period	30.26%	19.20%	+11.06%
Volatility (1Y) Calculated over the trailing 1-year period	52.84%	36.23%	+16.61%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	43.35%	33.47%	+9.88%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	49.47%	35.72%	+13.75%