CANC vs. GDOC

Last updated Apr 2, 2026

Compare and contrast key facts about Tema Oncology ETF (CANC) and Goldman Sachs Future Health Care Equity ETF (GDOC).

CANC and GDOC are both exchange-traded funds (ETFs), meaning they are traded on stock exchanges and can be bought and sold throughout the day. CANC is an actively managed fund by Tema. It was launched on Aug 14, 2023. GDOC is an actively managed fund by Goldman Sachs. It was launched on Nov 9, 2021.

Performance

CANC vs. GDOC - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Tema Oncology ETF (CANC) and Goldman Sachs Future Health Care Equity ETF (GDOC). The values are adjusted to include any dividend payments, if applicable.

CANC vs. GDOC - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021
CANC Tema Oncology ETF	6.91%	42.92%	-5.37%	510.51%	-85.34%	-44.79%
GDOC Goldman Sachs Future Health Care Equity ETF	-7.11%	10.74%	-1.66%	4.60%	-17.12%	-2.77%

Returns By Period

In the year-to-date period, CANC achieves a 6.91% return, which is significantly higher than GDOC's -7.11% return.

CANC

• 1D: 1.16%
• 1M: -0.89%
• YTD: 6.91%
• 6M: 27.17%
• 1Y: 58.38%
• 3Y*: 140.92%
• 5Y*: —
• 10Y*: —

GDOC

• 1D: 1.11%
• 1M: -3.59%
• YTD: -7.11%
• 6M: 0.33%
• 1Y: 4.43%
• 3Y*: 1.03%
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

CANC vs. GDOC - Expense Ratio Comparison

Both CANC and GDOC have an expense ratio of 0.75%.

CANC

Tema Oncology ETF

GDOC

Goldman Sachs Future Health Care Equity ETF

Return for Risk

CANC vs. GDOC — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

CANC

CANC Risk / Return Rank: 92
CANC Sharpe Ratio Rank: 92
CANC Sortino Ratio Rank: 92
CANC Omega Ratio Rank: 86
CANC Calmar Ratio Rank: 95
CANC Martin Ratio Rank: 94

GDOC

GDOC Risk / Return Rank: 16
GDOC Sharpe Ratio Rank: 17
GDOC Sortino Ratio Rank: 17
GDOC Omega Ratio Rank: 17
GDOC Calmar Ratio Rank: 15
GDOC Martin Ratio Rank: 15

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

CANC vs. GDOC - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Tema Oncology ETF (CANC) and Goldman Sachs Future Health Care Equity ETF (GDOC). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	CANC	GDOC	Difference
Sharpe ratio Return per unit of total volatility	2.17	0.24	+1.93
Sortino ratio Return per unit of downside risk	2.84	0.46	+2.38
Omega ratio Gain probability vs. loss probability	1.36	1.06	+0.30
Calmar ratio Return relative to maximum drawdown	4.37	0.18	+4.19
Martin ratio Return relative to average drawdown	15.21	0.55	+14.66
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

CANC vs. GDOC - Sharpe Ratio Comparison

The current CANC Sharpe Ratio is 2.17, which is higher than the GDOC Sharpe Ratio of 0.24. The chart below compares the historical Sharpe Ratios of CANC and GDOC, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	CANC	GDOC	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	2.17	0.24	+1.93
Sharpe Ratio (All Time) Calculated using the full available price history	-0.04	-0.19	+0.16

Correlation

The correlation between CANC and GDOC is 0.50, which is considered to be moderate. This suggests that the two assets have some degree of positive relationship in their price movements. Moderate correlation can be acceptable for portfolio diversification, offering a balance between risk and potential returns.

Dividends

CANC vs. GDOC - Dividend Comparison

CANC's dividend yield for the trailing twelve months is around 0.05%, less than GDOC's 0.34% yield.

	TTM	2025	2024	2023	2022
CANC Tema Oncology ETF	0.05%	0.06%	3.00%	0.56%	0.00%
GDOC Goldman Sachs Future Health Care Equity ETF	0.34%	0.32%	0.02%	0.55%	0.00%

Drawdowns

CANC vs. GDOC - Drawdown Comparison

The maximum CANC drawdown since its inception was -97.53%, which is greater than GDOC's maximum drawdown of -31.01%. Use the drawdown chart below to compare losses from any high point for CANC and GDOC.

Drawdown Indicators

	CANC	GDOC	Difference
Max Drawdown Largest peak-to-trough decline	-97.53%	-31.01%	-66.52%
Max Drawdown (1Y) Largest decline over 1 year	-12.40%	-14.57%	+2.17%
Current Drawdown Current decline from peak	-55.68%	-14.93%	-40.75%
Average Drawdown Average peak-to-trough decline	-73.89%	-15.90%	-57.99%
Ulcer Index Depth and duration of drawdowns from previous peaks	3.57%	4.86%	-1.29%

Volatility

CANC vs. GDOC - Volatility Comparison

Tema Oncology ETF (CANC) has a higher volatility of 8.20% compared to Goldman Sachs Future Health Care Equity ETF (GDOC) at 6.15%. This indicates that CANC's price experiences larger fluctuations and is considered to be riskier than GDOC based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	CANC	GDOC	Difference
Volatility (1M) Calculated over the trailing 1-month period	8.20%	6.15%	+2.05%
Volatility (6M) Calculated over the trailing 6-month period	16.22%	11.23%	+4.99%
Volatility (1Y) Calculated over the trailing 1-year period	27.19%	18.66%	+8.53%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	285.53%	18.82%	+266.71%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	285.53%	18.82%	+266.71%