AHCO vs. ANAB

Last updated Jun 4, 2026

AHCO (AdaptHealth Corp.) and ANAB (AnaptysBio, Inc.) are both stocks. Both are in the Healthcare sector — AHCO in Medical Devices, ANAB in Biotechnology. Over the past 5 years, AHCO returned -17.74%/yr vs 27.51%/yr for ANAB. At a 0.14 correlation, their price movements are largely independent.

Performance

AHCO vs. ANAB - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in AdaptHealth Corp. (AHCO) and AnaptysBio, Inc. (ANAB). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, AHCO achieves a -2.41% return, which is significantly lower than ANAB's 58.54% return.

AHCO

• 1D: 0.73%
• 1M: -25.46%
• YTD: -2.41%
• 6M: 4.07%
• 1Y: 9.71%
• 3Y*: -2.54%
• 5Y*: -17.74%
• 10Y*: —

ANAB

• 1D: -0.04%
• 1M: -26.57%
• YTD: 58.54%
• 6M: 75.64%
• 1Y: 226.79%
• 3Y*: 60.13%
• 5Y*: 27.51%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

AHCO vs. ANAB - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018
AHCO AdaptHealth Corp.	-2.41%	4.62%	30.59%	-62.07%	-21.42%	-34.88%	242.08%	11.70%	1.34%
ANAB AnaptysBio, Inc.	58.54%	266.16%	-38.19%	-30.88%	-10.82%	61.63%	32.31%	-74.53%	-22.84%

Correlation

The correlation between AHCO and ANAB is 0.13, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.13
Correlation (3Y) Calculated over the trailing 3-year period	0.15
Correlation (5Y) Calculated over the trailing 5-year period	0.19
Correlation (All Time) Calculated using the full available price history since May 25, 2018	0.14

Fundamentals

Market Cap AHCO : $1.32B ANAB : $1.47B
EPS AHCO : -$0.60 ANAB : -$0.91
PS Ratio AHCO : 0.43 ANAB : 6.50
PB Ratio AHCO : 0.87 ANAB : 115.33
Total Revenue (TTM) AHCO : $3.08B ANAB : $232.39M
Gross Profit (TTM) AHCO : $260.17M ANAB : $245.59M
EBITDA (TTM) AHCO : $380.93M ANAB : $52.72M

Return for Risk

AHCO vs. ANAB — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

AHCO

AHCO Risk / Return Rank: 48
AHCO Sharpe Ratio Rank: 48
AHCO Sortino Ratio Rank: 46
AHCO Omega Ratio Rank: 45
AHCO Calmar Ratio Rank: 49
AHCO Martin Ratio Rank: 53

ANAB

ANAB Risk / Return Rank: 94
ANAB Sharpe Ratio Rank: 95
ANAB Sortino Ratio Rank: 93
ANAB Omega Ratio Rank: 92
ANAB Calmar Ratio Rank: 96
ANAB Martin Ratio Rank: 96

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

AHCO vs. ANAB - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for AdaptHealth Corp. (AHCO) and AnaptysBio, Inc. (ANAB). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	AHCO	ANAB	Difference
Sharpe ratio Return per unit of total volatility	0.21	3.24	-3.03
Sortino ratio Return per unit of downside risk	0.67	3.63	-2.96
Omega ratio Gain probability vs. loss probability	1.08	1.48	-0.40
Calmar ratio Return relative to maximum drawdown	0.35	8.11	-7.76
Martin ratio Return relative to average drawdown	1.06	20.93	-19.88
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

AHCO vs. ANAB - Sharpe Ratio Comparison

The current AHCO Sharpe Ratio is 0.21, which is lower than the ANAB Sharpe Ratio of 3.24. The chart below compares the historical Sharpe Ratios of AHCO and ANAB, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	AHCO	ANAB	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	0.21	3.24	-3.03
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.31	0.42	-0.73
Sharpe Ratio (All Time) Calculated using the full available price history	0.00	0.23	-0.23

Drawdowns

AHCO vs. ANAB - Drawdown Comparison

The maximum AHCO drawdown since its inception was -83.84%, smaller than the maximum ANAB drawdown of -92.08%. Use the drawdown chart below to compare losses from any high point for AHCO and ANAB.

Drawdown Indicators

	AHCO	ANAB	Difference
Max Drawdown Largest peak-to-trough decline	-83.84%	-92.08%	+8.24%
Max Drawdown (1Y) Largest decline over 1 year	-27.88%	-28.15%	+0.27%
Max Drawdown (3Y) Largest decline over 3 years	-56.06%	-69.32%	+13.26%
Max Drawdown (5Y) Largest decline over 5 years	-78.29%	-69.32%	-8.97%
Current Drawdown Current decline from peak	-75.79%	-40.21%	-35.58%
Average Drawdown Average peak-to-trough decline	-43.23%	-64.74%	+21.51%
Ulcer Index Depth and duration of drawdowns from previous peaks	9.21%	10.92%	-1.71%

Volatility

AHCO vs. ANAB - Volatility Comparison

AdaptHealth Corp. (AHCO) has a higher volatility of 12.42% compared to AnaptysBio, Inc. (ANAB) at 11.47%. This indicates that AHCO's price experiences larger fluctuations and is considered to be riskier than ANAB based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	AHCO	ANAB	Difference
Volatility (1M) Calculated over the trailing 1-month period	12.42%	11.47%	+0.95%
Volatility (6M) Calculated over the trailing 6-month period	33.27%	46.57%	-13.30%
Volatility (1Y) Calculated over the trailing 1-year period	46.49%	70.75%	-24.26%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	58.22%	65.34%	-7.12%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	54.80%	75.51%	-20.71%

Dividends

AHCO vs. ANAB - Dividend Comparison

Neither AHCO nor ANAB has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both AHCO and ANAB in my portfolio?

AHCO and ANAB have a correlation of 0.13, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, AHCO or ANAB?

AHCO has higher volatility (12.42%) compared to ANAB (11.47%). In terms of maximum drawdown, AHCO dropped -83.84% vs ANAB's -92.08%.

Which has better risk-adjusted returns?

ANAB currently has the higher Sharpe Ratio (3.24 vs 0.21), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.