XLV vs. CNCR

Last updated Apr 2, 2026

Compare and contrast key facts about State Street Health Care Select Sector SPDR ETF (XLV) and Loncar Cancer Immunotherapy ETF (CNCR).

XLV and CNCR are both exchange-traded funds (ETFs), meaning they are traded on stock exchanges and can be bought and sold throughout the day. XLV is a passively managed fund by State Street that tracks the performance of the Health Care Select Sector Index. It was launched on Dec 16, 1998. CNCR is a passively managed fund by Exchange Traded Concepts that tracks the performance of the Loncar Cancer Immunotherapy Index. It was launched on Oct 13, 2015. Both XLV and CNCR are passive ETFs, meaning that they are not actively managed but aim to replicate the performance of the underlying index as closely as possible.

Performance

XLV vs. CNCR - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in State Street Health Care Select Sector SPDR ETF (XLV) and Loncar Cancer Immunotherapy ETF (CNCR). The values are adjusted to include any dividend payments, if applicable.

XLV vs. CNCR - Yearly Performance Comparison

	2026 (YTD)
XLV State Street Health Care Select Sector SPDR ETF	-5.94%
CNCR Loncar Cancer Immunotherapy ETF	0.00%

Returns By Period

XLV

• 1D: 0.76%
• 1M: -6.43%
• YTD: -4.18%
• 6M: 3.83%
• 1Y: 4.90%
• 3Y*: 6.25%
• 5Y*: 6.59%
• 10Y*: 9.80%

CNCR

• 1D: 0.00%
• 1M: 0.00%
• YTD: —
• 6M: —
• 1Y: —
• 3Y*: —
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

XLV vs. CNCR - Expense Ratio Comparison

XLV has a 0.08% expense ratio, which is lower than CNCR's 0.79% expense ratio.

CNCR

Loncar Cancer Immunotherapy ETF

XLV

State Street Health Care Select Sector SPDR ETF

Return for Risk

XLV vs. CNCR — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

XLV

XLV Risk / Return Rank: 18
XLV Sharpe Ratio Rank: 19
XLV Sortino Ratio Rank: 18
XLV Omega Ratio Rank: 18
XLV Calmar Ratio Rank: 17
XLV Martin Ratio Rank: 16

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

XLV vs. CNCR - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for State Street Health Care Select Sector SPDR ETF (XLV) and Loncar Cancer Immunotherapy ETF (CNCR). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	XLV	CNCR	Difference
Sharpe ratio Return per unit of total volatility	0.28	—	—
Sortino ratio Return per unit of downside risk	0.51	—	—
Omega ratio Gain probability vs. loss probability	1.06	—	—
Calmar ratio Return relative to maximum drawdown	0.28	—	—
Martin ratio Return relative to average drawdown	0.58	—	—
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

Sharpe Ratios by Period

	XLV	CNCR	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	0.28	—	—
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.45	—	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.59	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	0.46	—	—

Dividends

XLV vs. CNCR - Dividend Comparison

XLV's dividend yield for the trailing twelve months is around 1.70%, while CNCR has not paid dividends to shareholders.

	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
XLV State Street Health Care Select Sector SPDR ETF	1.70%	1.60%	1.67%	1.59%	1.47%	1.33%	1.49%	2.17%	1.57%	1.47%	1.60%	1.43%
CNCR Loncar Cancer Immunotherapy ETF	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Drawdowns

XLV vs. CNCR - Drawdown Comparison

The maximum XLV drawdown since its inception was -39.17%, which is greater than CNCR's maximum drawdown of 0.00%. Use the drawdown chart below to compare losses from any high point for XLV and CNCR.

Drawdown Indicators

	XLV	CNCR	Difference
Max Drawdown Largest peak-to-trough decline	-39.17%	0.00%	-39.17%
Max Drawdown (1Y) Largest decline over 1 year	-10.76%	—	—
Max Drawdown (5Y) Largest decline over 5 years	-17.11%	—	—
Max Drawdown (10Y) Largest decline over 10 years	-28.40%	—	—
Current Drawdown Current decline from peak	-7.41%	0.00%	-7.41%
Average Drawdown Average peak-to-trough decline	-7.12%	0.00%	-7.12%
Ulcer Index Depth and duration of drawdowns from previous peaks	5.11%	—	—

Volatility

Volatility by Period

	XLV	CNCR	Difference
Volatility (1M) Calculated over the trailing 1-month period	4.79%	—	—
Volatility (6M) Calculated over the trailing 6-month period	10.29%	—	—
Volatility (1Y) Calculated over the trailing 1-year period	17.73%	0.00%	+17.73%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	14.56%	0.00%	+14.56%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	16.53%	0.00%	+16.53%