VYNE vs. VT
VYNE (VYNE Therapeutics Inc.) is a stock, while VT (Vanguard Total World Stock ETF) is Global Equities fund tracking the FTSE Global All Cap Index. Over the past 5 years, VYNE returned -60.40%/yr vs 10.51%/yr for VT. At a 0.25 correlation, their price movements are largely independent.
Performance
VYNE vs. VT - Performance Comparison
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Returns By Period
In the year-to-date period, VYNE achieves a 12.05% return, which is significantly higher than VT's 10.06% return.
VYNE
- 1D
- 0.00%
- 1M
- -3.19%
- YTD
- 12.05%
- 6M
- 14.36%
- 1Y
- -28.89%
- 3Y*
- -48.75%
- 5Y*
- -60.40%
- 10Y*
- —
VT
- 1D
- -2.05%
- 1M
- -0.44%
- YTD
- 10.06%
- 6M
- 9.32%
- 1Y
- 25.71%
- 3Y*
- 19.92%
- 5Y*
- 10.51%
- 10Y*
- 12.96%
VYNE vs. VT - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | |
|---|---|---|---|---|---|---|---|---|---|
VYNE VYNE Therapeutics Inc. | 12.05% | -82.68% | 43.78% | -13.70% | -85.29% | -83.86% | -65.95% | 12.62% | -79.90% |
VT Vanguard Total World Stock ETF | 10.06% | 22.43% | 16.49% | 22.02% | -18.00% | 18.27% | 16.59% | 26.81% | -15.22% |
Correlation
The correlation between VYNE and VT is 0.20, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.20 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.19 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.24 |
Correlation (All Time) Calculated using the full available price history since Jan 25, 2018 | 0.25 |
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Return for Risk
VYNE vs. VT — Risk / Return Rank
VYNE
VT
VYNE vs. VT - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for VYNE Therapeutics Inc. (VYNE) and Vanguard Total World Stock ETF (VT). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| VYNE | VT | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -2.16 | ||
| Sortino ratioReturn per unit of downside risk | -1.92 | ||
| Omega ratioGain probability vs. loss probability | 1.15 | 1.35 | -0.20 |
| Calmar ratioReturn relative to maximum drawdown | -0.35 | 2.67 | -3.02 |
| Martin ratioReturn relative to average drawdown | -0.42 | 11.57 | -11.99 |
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Drawdowns
VYNE vs. VT - Drawdown Comparison
The maximum VYNE drawdown since its inception was -99.99%, which is greater than VT's maximum drawdown of -50.27%. Use the drawdown chart below to compare losses from any high point for VYNE and VT.
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Drawdown Indicators
| VYNE | VT | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -99.99% | -50.27% | -49.72% |
Max Drawdown (1Y)Largest decline over 1 year | -83.79% | -9.67% | -74.12% |
Max Drawdown (3Y)Largest decline over 3 years | -95.22% | -16.51% | -78.71% |
Max Drawdown (5Y)Largest decline over 5 years | -99.57% | -26.38% | -73.19% |
Max Drawdown (10Y)Largest decline over 10 years | — | -34.24% | — |
Current DrawdownCurrent decline from peak | -99.98% | -2.80% | -97.18% |
Average DrawdownAverage peak-to-trough decline | -93.08% | -7.00% | -86.08% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 68.72% | 2.23% | +66.49% |
Volatility
VYNE vs. VT - Volatility Comparison
VYNE Therapeutics Inc. (VYNE) has a higher volatility of 7.73% compared to Vanguard Total World Stock ETF (VT) at 5.65%. This indicates that VYNE's price experiences larger fluctuations and is considered to be riskier than VT based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| VYNE | VT | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 7.73% | 5.65% | +2.08% |
Volatility (6M)Calculated over the trailing 6-month period | 19.58% | 11.32% | +8.26% |
Volatility (1Y)Calculated over the trailing 1-year period | 115.35% | 13.58% | +101.77% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 105.06% | 16.19% | +88.87% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 103.94% | 17.20% | +86.74% |
Dividends
VYNE vs. VT - Dividend Comparison
VYNE has not paid dividends to shareholders, while VT's dividend yield for the trailing twelve months is around 1.61%.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
VT Vanguard Total World Stock ETF | 1.61% | 1.82% | 1.95% | 2.08% | 2.20% | 1.82% | 1.66% | 2.32% | 2.53% | 2.11% | 2.39% | 2.45% |
VYNE VYNE Therapeutics Inc. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
Frequently Asked Questions
VYNE and VT have a correlation of 0.20, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
VYNE has higher volatility (7.73%) compared to VT (5.65%). In terms of maximum drawdown, VYNE dropped -99.99% vs VT's -50.27%.
VT currently has the higher Sharpe Ratio (1.91 vs -0.25), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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