VYNE vs. VGSTX
VYNE (VYNE Therapeutics Inc.) is a stock, while VGSTX (Vanguard STAR Fund) is Diversified Portfolio fund actively managed by Vanguard. Over the past 5 years, VYNE returned -54.99%/yr vs 6.25%/yr for VGSTX. At a 0.26 correlation, their price movements are largely independent.
Performance
VYNE vs. VGSTX - Performance Comparison
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Returns By Period
In the year-to-date period, VYNE achieves a 54.73% return, which is significantly higher than VGSTX's 5.79% return.
VYNE
- 1D
- 0.55%
- 1M
- 38.09%
- 6M
- 54.84%
- YTD
- 54.73%
- 1Y
- -19.86%
- 3Y*
- -39.43%
- 5Y*
- -54.99%
- 10Y*
- —
- ALL TIME*
- -58.21%
VGSTX
- 1D
- 0.56%
- 1M
- 0.06%
- 6M
- 4.36%
- YTD
- 5.79%
- 1Y
- 13.49%
- 3Y*
- 13.25%
- 5Y*
- 6.25%
- 10Y*
- 9.34%
- ALL TIME*
- 8.80%
Liquidity Comparison
| Position | Avg. Volume Value (2W) | Avg. Volume Value (1M) | Avg. Volume Value (3M) |
|---|---|---|---|
VGSTX Vanguard STAR Fund | $0.00 | $0.00 | $0.00 |
| $2.46M | $1.23M | $501.33K |
VYNE vs. VGSTX - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | |
|---|---|---|---|---|---|---|---|---|---|
VYNE VYNE Therapeutics Inc. | 54.73% | -82.68% | 43.78% | -13.70% | -85.29% | -83.86% | -65.95% | 12.62% | -79.90% |
VGSTX Vanguard STAR Fund | 5.79% | 15.88% | 13.69% | 17.14% | -18.05% | 9.65% | 21.45% | 22.21% | -9.03% |
Correlation
The correlation between VYNE and VGSTX is 0.20, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.20 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.20 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.24 |
Correlation (All Time) Calculated using the full available price history since Jan 25, 2018 | 0.26 |
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Return for Risk
VYNE vs. VGSTX — Risk / Return Rank
VYNE
VGSTX
VYNE vs. VGSTX - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for VYNE Therapeutics Inc. (VYNE) and Vanguard STAR Fund (VGSTX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| VYNE | VGSTX | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -1.73 | ||
| Sortino ratioReturn per unit of downside risk | -1.45 | ||
| Omega ratioGain probability vs. loss probability | 1.18 | 1.28 | -0.09 |
| Calmar ratioReturn relative to maximum drawdown | -0.25 | 2.05 | -2.30 |
| Martin ratioReturn relative to average drawdown | -0.31 | 8.71 | -9.02 |
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Drawdowns
VYNE vs. VGSTX - Drawdown Comparison
The maximum VYNE drawdown since its inception was -99.99%, which is greater than VGSTX's maximum drawdown of -38.62%. Use the drawdown chart below to compare losses from any high point for VYNE and VGSTX.
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Drawdown Indicators
| VYNE | VGSTX | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -99.99% | -38.62% | -61.37% |
Max Drawdown (1Y)Largest decline over 1 year | -80.34% | -6.76% | -73.58% |
Max Drawdown (3Y)Largest decline over 3 years | -95.22% | -11.77% | -83.45% |
Max Drawdown (5Y)Largest decline over 5 years | -99.45% | -25.55% | -73.90% |
Max Drawdown (10Y)Largest decline over 10 years | — | -25.55% | — |
Current DrawdownCurrent decline from peak | -99.97% | -1.13% | -98.84% |
Average DrawdownAverage peak-to-trough decline | -93.14% | -4.02% | -89.12% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 64.61% | 1.59% | +63.02% |
Volatility
VYNE vs. VGSTX - Volatility Comparison
VYNE Therapeutics Inc. (VYNE) has a higher volatility of 16.85% compared to Vanguard STAR Fund (VGSTX) at 2.15%. This indicates that VYNE's price experiences larger fluctuations and is considered to be riskier than VGSTX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| VYNE | VGSTX | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 16.85% | 2.15% | +14.70% |
Volatility (6M)Calculated over the trailing 6-month period | 25.04% | 7.38% | +17.66% |
Volatility (1Y)Calculated over the trailing 1-year period | 105.76% | 8.97% | +96.79% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 105.21% | 11.89% | +93.32% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 103.65% | 11.80% | +91.85% |
Dividends
VYNE vs. VGSTX - Dividend Comparison
VYNE has not paid dividends to shareholders, while VGSTX's dividend yield for the trailing twelve months is around 8.59%.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
VGSTX Vanguard STAR Fund | 8.59% | 9.13% | 10.67% | 5.35% | 8.34% | 6.70% | 6.68% | 6.07% | 6.90% | 3.32% | 4.77% | 5.62% |
VYNE VYNE Therapeutics Inc. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
Frequently Asked Questions
VYNE and VGSTX have a correlation of 0.20, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
VYNE has higher volatility (16.85%) compared to VGSTX (2.15%). In terms of maximum drawdown, VYNE dropped -99.99% vs VGSTX's -38.62%.
VGSTX currently has the higher Sharpe Ratio (1.54 vs -0.19), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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