VYNE vs. VGSTX
VYNE (VYNE Therapeutics Inc.) is a stock, while VGSTX (Vanguard STAR Fund) is Diversified Portfolio fund actively managed by Vanguard. Over the past 5 years, VYNE returned -60.40%/yr vs 6.44%/yr for VGSTX. At a 0.26 correlation, their price movements are largely independent.
Performance
VYNE vs. VGSTX - Performance Comparison
Loading charts...
Returns By Period
In the year-to-date period, VYNE achieves a 12.05% return, which is significantly higher than VGSTX's 5.73% return.
VYNE
- 1D
- 0.00%
- 1M
- -3.19%
- YTD
- 12.05%
- 6M
- 14.36%
- 1Y
- -28.89%
- 3Y*
- -48.75%
- 5Y*
- -60.40%
- 10Y*
- —
VGSTX
- 1D
- -0.29%
- 1M
- 1.05%
- YTD
- 5.73%
- 6M
- 5.40%
- 1Y
- 16.70%
- 3Y*
- 14.40%
- 5Y*
- 6.44%
- 10Y*
- 9.86%
VYNE vs. VGSTX - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | |
|---|---|---|---|---|---|---|---|---|---|
VYNE VYNE Therapeutics Inc. | 12.05% | -82.68% | 43.78% | -13.70% | -85.29% | -83.86% | -65.95% | 12.62% | -79.90% |
VGSTX Vanguard STAR Fund | 5.73% | 15.88% | 13.69% | 17.14% | -18.05% | 9.65% | 21.45% | 22.21% | -9.03% |
Correlation
The correlation between VYNE and VGSTX is 0.21, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.21 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.20 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.24 |
Correlation (All Time) Calculated using the full available price history since Jan 25, 2018 | 0.26 |
Compare stocks, funds, or ETFs
Search for stocks, ETFs, and funds for a quick comparison or use the comparison tool for more options.
Return for Risk
VYNE vs. VGSTX — Risk / Return Rank
VYNE
VGSTX
VYNE vs. VGSTX - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for VYNE Therapeutics Inc. (VYNE) and Vanguard STAR Fund (VGSTX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| VYNE | VGSTX | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -2.21 | ||
| Sortino ratioReturn per unit of downside risk | -2.08 | ||
| Omega ratioGain probability vs. loss probability | 1.15 | 1.36 | -0.21 |
| Calmar ratioReturn relative to maximum drawdown | -0.35 | 2.58 | -2.93 |
| Martin ratioReturn relative to average drawdown | -0.42 | 11.11 | -11.53 |
Loading charts...
Drawdowns
VYNE vs. VGSTX - Drawdown Comparison
The maximum VYNE drawdown since its inception was -99.99%, which is greater than VGSTX's maximum drawdown of -38.62%. Use the drawdown chart below to compare losses from any high point for VYNE and VGSTX.
Loading charts...
Drawdown Indicators
| VYNE | VGSTX | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -99.99% | -38.62% | -61.37% |
Max Drawdown (1Y)Largest decline over 1 year | -83.79% | -6.76% | -77.03% |
Max Drawdown (3Y)Largest decline over 3 years | -95.22% | -11.77% | -83.45% |
Max Drawdown (5Y)Largest decline over 5 years | -99.57% | -25.55% | -74.02% |
Max Drawdown (10Y)Largest decline over 10 years | — | -25.55% | — |
Current DrawdownCurrent decline from peak | -99.98% | -0.71% | -99.27% |
Average DrawdownAverage peak-to-trough decline | -93.08% | -4.03% | -89.05% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 68.72% | 1.57% | +67.15% |
Volatility
VYNE vs. VGSTX - Volatility Comparison
VYNE Therapeutics Inc. (VYNE) has a higher volatility of 7.73% compared to Vanguard STAR Fund (VGSTX) at 3.30%. This indicates that VYNE's price experiences larger fluctuations and is considered to be riskier than VGSTX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
Loading charts...
Volatility by Period
| VYNE | VGSTX | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 7.73% | 3.30% | +4.43% |
Volatility (6M)Calculated over the trailing 6-month period | 19.58% | 7.24% | +12.34% |
Volatility (1Y)Calculated over the trailing 1-year period | 115.35% | 8.92% | +106.43% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 105.06% | 11.89% | +93.17% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 103.94% | 11.86% | +92.08% |
Dividends
VYNE vs. VGSTX - Dividend Comparison
VYNE has not paid dividends to shareholders, while VGSTX's dividend yield for the trailing twelve months is around 8.63%.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
VGSTX Vanguard STAR Fund | 8.63% | 9.13% | 10.67% | 5.35% | 8.34% | 6.70% | 6.68% | 6.07% | 6.90% | 3.32% | 4.77% | 5.62% |
VYNE VYNE Therapeutics Inc. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
Frequently Asked Questions
VYNE and VGSTX have a correlation of 0.21, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
VYNE has higher volatility (7.73%) compared to VGSTX (3.30%). In terms of maximum drawdown, VYNE dropped -99.99% vs VGSTX's -38.62%.
VGSTX currently has the higher Sharpe Ratio (1.96 vs -0.25), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
Find the right allocation for VYNE and VGSTX
Add both to a portfolio and optimize allocations for your target — whether that's maximizing returns, minimizing drawdowns, or balancing risk across holdings.
Open Portfolio Optimizer