VYNE vs. MURA
VYNE (VYNE Therapeutics Inc.) and MURA (Mural Oncology plc) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. Over the past year, VYNE returned -27.16% vs -22.43% for MURA. At a 0.18 correlation, their price movements are largely independent.
Performance
VYNE vs. MURA - Performance Comparison
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Returns By Period
VYNE
- 1D
- -1.00%
- 1M
- 5.43%
- YTD
- 16.53%
- 6M
- 88.99%
- 1Y
- -27.16%
- 3Y*
- -51.86%
- 5Y*
- -60.57%
- 10Y*
- —
MURA
- 1D
- 0.00%
- 1M
- 0.00%
- YTD
- 0.00%
- 6M
- 0.49%
- 1Y
- -22.43%
- 3Y*
- —
- 5Y*
- —
- 10Y*
- —
VYNE vs. MURA - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | |
|---|---|---|---|---|
VYNE VYNE Therapeutics Inc. | 16.53% | -82.68% | 43.78% | -41.46% |
MURA Mural Oncology plc | 0.00% | -36.65% | -45.61% | 55.79% |
Correlation
The correlation between VYNE and MURA is 0.17, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.17 |
Correlation (All Time) Calculated using the full available price history since Nov 17, 2023 | 0.18 |
Fundamentals
VYNE:
$28.91M
MURA:
$35.34M
VYNE:
-$0.50
MURA:
-$6.89
VYNE:
1.17
MURA:
0.64
VYNE:
$454.00K
MURA:
$0.00
VYNE:
$363.00K
MURA:
-$1.10M
VYNE:
-$23.76M
MURA:
-$118.31M
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Return for Risk
VYNE vs. MURA — Risk / Return Rank
VYNE
MURA
VYNE vs. MURA - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for VYNE Therapeutics Inc. (VYNE) and Mural Oncology plc (MURA). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| VYNE | MURA | Difference | |
|---|---|---|---|
Sharpe ratioReturn per unit of total volatility | -0.24 | -0.75 | +0.51 |
Sortino ratioReturn per unit of downside risk | 0.73 | -0.91 | +1.64 |
Omega ratioGain probability vs. loss probability | 1.16 | 0.78 | +0.37 |
Calmar ratioReturn relative to maximum drawdown | -0.34 | 1.11 | -1.46 |
Martin ratioReturn relative to average drawdown | -0.43 | 1.98 | -2.41 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| VYNE | MURA | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | -0.24 | -0.75 | +0.51 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | -0.58 | — | — |
Sharpe Ratio (All Time)Calculated using the full available price history | -0.60 | -0.21 | -0.39 |
Drawdowns
VYNE vs. MURA - Drawdown Comparison
The maximum VYNE drawdown since its inception was -99.99%, which is greater than MURA's maximum drawdown of -83.44%. Use the drawdown chart below to compare losses from any high point for VYNE and MURA.
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Drawdown Indicators
| VYNE | MURA | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -99.99% | -83.44% | -16.55% |
Max Drawdown (1Y)Largest decline over 1 year | -83.79% | -41.06% | -42.73% |
Max Drawdown (3Y)Largest decline over 3 years | -95.26% | — | — |
Max Drawdown (5Y)Largest decline over 5 years | -99.61% | — | — |
Current DrawdownCurrent decline from peak | -99.98% | -66.06% | -33.92% |
Average DrawdownAverage peak-to-trough decline | -93.08% | -47.65% | -45.43% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 67.10% | 26.97% | +40.13% |
Volatility
VYNE vs. MURA - Volatility Comparison
VYNE Therapeutics Inc. (VYNE) has a higher volatility of 4.64% compared to Mural Oncology plc (MURA) at 0.00%. This indicates that VYNE's price experiences larger fluctuations and is considered to be riskier than MURA based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| VYNE | MURA | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 4.64% | 0.00% | +4.64% |
Volatility (6M)Calculated over the trailing 6-month period | 47.16% | 5.09% | +42.07% |
Volatility (1Y)Calculated over the trailing 1-year period | 115.76% | 35.65% | +80.11% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 105.06% | 112.72% | -7.66% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 103.35% | 112.72% | -9.37% |
Dividends
VYNE vs. MURA - Dividend Comparison
Neither VYNE nor MURA has paid dividends to shareholders.
Financials
VYNE vs. MURA - Financials Comparison
This section allows you to compare key financial metrics between VYNE Therapeutics Inc. and Mural Oncology plc. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
Frequently Asked Questions
VYNE and MURA have a correlation of 0.17, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
VYNE has higher volatility (4.64%) compared to MURA (0.00%). In terms of maximum drawdown, VYNE dropped -99.99% vs MURA's -83.44%.
VYNE currently has the higher Sharpe Ratio (-0.24 vs -0.75), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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