MURA vs. IRON

Last updated Jun 3, 2026

MURA (Mural Oncology plc) and IRON (Disc Medicine Inc.) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. Over the past year, MURA returned -22.43% vs 42.47% for IRON. At a 0.14 correlation, their price movements are largely independent.

Performance

MURA vs. IRON - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Mural Oncology plc (MURA) and Disc Medicine Inc. (IRON). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

MURA

• 1D: 0.00%
• 1M: 0.00%
• YTD: 0.00%
• 6M: 0.49%
• 1Y: -22.43%
• 3Y*: —
• 5Y*: —
• 10Y*: —

IRON

• 1D: -5.52%
• 1M: 1.63%
• YTD: -14.37%
• 6M: -24.21%
• 1Y: 42.47%
• 3Y*: 18.69%
• 5Y*: -11.63%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

MURA vs. IRON - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023
MURA Mural Oncology plc	0.00%	-36.65%	-45.61%	55.79%
IRON Disc Medicine Inc.	-14.37%	25.25%	9.76%	19.44%

Correlation

The correlation between MURA and IRON is -0.02, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	-0.02
Correlation (All Time) Calculated using the full available price history since Nov 17, 2023	0.14

The correlation between MURA and IRON shifts across timeframes, from -0.02 (1 year) to 0.14 (all time), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap MURA : $35.34M IRON : $2.62B
EPS MURA : -$6.89 IRON : -$6.71
PB Ratio MURA : 0.64 IRON : 3.80
Total Revenue (TTM) MURA : $0.00 IRON : $0.00
Gross Profit (TTM) MURA : -$1.10M IRON : -$265.00K
EBITDA (TTM) MURA : -$118.31M IRON : -$243.47M

Return for Risk

MURA vs. IRON — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

MURA

MURA Risk / Return Rank: 30
MURA Sharpe Ratio Rank: 10
MURA Sortino Ratio Rank: 12
MURA Omega Ratio Rank: 4
MURA Calmar Ratio Rank: 63
MURA Martin Ratio Rank: 59

IRON

IRON Risk / Return Rank: 64
IRON Sharpe Ratio Rank: 66
IRON Sortino Ratio Rank: 62
IRON Omega Ratio Rank: 64
IRON Calmar Ratio Rank: 63
IRON Martin Ratio Rank: 63

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

MURA vs. IRON - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Mural Oncology plc (MURA) and Disc Medicine Inc. (IRON). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	MURA	IRON	Difference
Sharpe ratio Return per unit of total volatility	-0.75	0.80	-1.55
Sortino ratio Return per unit of downside risk	-0.91	1.38	-2.29
Omega ratio Gain probability vs. loss probability	0.78	1.20	-0.41
Calmar ratio Return relative to maximum drawdown	1.11	1.13	-0.01
Martin ratio Return relative to average drawdown	1.98	2.52	-0.54
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

MURA vs. IRON - Sharpe Ratio Comparison

The current MURA Sharpe Ratio is -0.75, which is lower than the IRON Sharpe Ratio of 0.80. The chart below compares the historical Sharpe Ratios of MURA and IRON, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	MURA	IRON	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.75	0.80	-1.55
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	—	-0.16	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.21	-0.10	-0.11

Drawdowns

MURA vs. IRON - Drawdown Comparison

The maximum MURA drawdown since its inception was -83.44%, smaller than the maximum IRON drawdown of -93.22%. Use the drawdown chart below to compare losses from any high point for MURA and IRON.

Drawdown Indicators

	MURA	IRON	Difference
Max Drawdown Largest peak-to-trough decline	-83.44%	-93.22%	+9.78%
Max Drawdown (1Y) Largest decline over 1 year	-41.06%	-40.55%	-0.51%
Max Drawdown (3Y) Largest decline over 3 years	—	-64.79%	—
Max Drawdown (5Y) Largest decline over 5 years	—	-90.33%	—
Current Drawdown Current decline from peak	-66.06%	-62.22%	-3.84%
Average Drawdown Average peak-to-trough decline	-47.65%	-66.49%	+18.84%
Ulcer Index Depth and duration of drawdowns from previous peaks	26.97%	18.09%	+8.88%

Volatility

MURA vs. IRON - Volatility Comparison

The current volatility for Mural Oncology plc (MURA) is 0.00%, while Disc Medicine Inc. (IRON) has a volatility of 11.66%. This indicates that MURA experiences smaller price fluctuations and is considered to be less risky than IRON based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	MURA	IRON	Difference
Volatility (1M) Calculated over the trailing 1-month period	0.00%	11.66%	-11.66%
Volatility (6M) Calculated over the trailing 6-month period	5.09%	43.57%	-38.48%
Volatility (1Y) Calculated over the trailing 1-year period	35.65%	53.48%	-17.83%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	112.72%	71.03%	+41.69%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	112.72%	69.60%	+43.12%

Dividends

MURA vs. IRON - Dividend Comparison

Neither MURA nor IRON has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both MURA and IRON in my portfolio?

MURA and IRON have a correlation of -0.02, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, MURA or IRON?

IRON has higher volatility (11.66%) compared to MURA (0.00%). In terms of maximum drawdown, MURA dropped -83.44% vs IRON's -93.22%.

Which has better risk-adjusted returns?

IRON currently has the higher Sharpe Ratio (0.80 vs -0.75), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.