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VCYT vs. CDNA
Performance
Return for Risk
Drawdowns
Volatility
Dividends
Financials

Performance

VCYT vs. CDNA - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Veracyte, Inc. (VCYT) and CareDx, Inc (CDNA). The values are adjusted to include any dividend payments, if applicable.

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Returns By Period

In the year-to-date period, VCYT achieves a 10.02% return, which is significantly lower than CDNA's 132.01% return. Both investments have delivered pretty close results over the past 10 years, with VCYT having a 25.08% annualized return and CDNA not far behind at 25.04%.


VCYT

1D
-22.52%
1M
-18.85%
6M
21.64%
YTD
10.02%
1Y
95.94%
3Y*
19.65%
5Y*
0.78%
10Y*
25.08%
ALL TIME*
10.48%

CDNA

1D
14.72%
1M
49.74%
6M
112.70%
YTD
132.01%
1Y
257.69%
3Y*
60.92%
5Y*
-12.26%
10Y*
25.04%
ALL TIME*
13.52%
*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison


PositionAvg. Volume Value (2W)Avg. Volume Value (1M)Avg. Volume Value (3M)
$44.41M$43.11M$27.26M
$76.67M$68.47M$67.41M

VCYT vs. CDNA - Yearly Performance Comparison


2026 (YTD)202520242023202220212020201920182017
VCYT
Veracyte, Inc.
10.02%6.31%43.95%15.93%-42.40%-15.82%75.29%121.94%92.65%-15.63%
CDNA
CareDx, Inc
132.01%-12.00%78.42%5.17%-74.91%-37.23%235.88%-14.20%242.51%171.85%

Correlation

The correlation between VCYT and CDNA is 0.49, which is low. Their historical price movements had little consistent relationship.


Correlation
Correlation (1Y)
Focuses on recent behavior, but can change the most.

0.49

Correlation (3Y)
Balances recent behavior with more history.

0.53

Correlation (5Y)
Shows whether the relationship held over a longer period.

0.62

Correlation (10Y)
Provides a long-term view across more market conditions.

0.48

Correlation (All Time)
Calculated using the full available price history since Jul 17, 2014

0.43

The correlation between VCYT and CDNA shifts across timeframes, from 0.43 (all time) to 0.62 (5 years), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap

VCYT:

$3.70B

CDNA:

$2.26B

EPS

VCYT:

$1.41

CDNA:

$2.10

PE Ratio

VCYT:

32.79

CDNA:

20.81

PEG Ratio

VCYT:

0.20

CDNA:

0.03

PS Ratio

VCYT:

6.68

CDNA:

5.04

PB Ratio

VCYT:

2.73

CDNA:

5.49

Total Revenue (TTM)

VCYT:

$561.90M

CDNA:

$458.09M

Gross Profit (TTM)

VCYT:

$405.67M

CDNA:

$225.02M

EBITDA (TTM)

VCYT:

$126.58M

CDNA:

$129.64M

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Return for Risk

VCYT vs. CDNA — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

VCYT
VCYT Risk / Return Rank: 8484
Overall Rank
VCYT Sharpe Ratio Rank: 8585
Sharpe Ratio Rank
VCYT Sortino Ratio Rank: 8686
Sortino Ratio Rank
VCYT Omega Ratio Rank: 8686
Omega Ratio Rank
VCYT Calmar Ratio Rank: 8383
Calmar Ratio Rank
VCYT Martin Ratio Rank: 8181
Martin Ratio Rank

CDNA
CDNA Risk / Return Rank: 9898
Overall Rank
CDNA Sharpe Ratio Rank: 9898
Sharpe Ratio Rank
CDNA Sortino Ratio Rank: 9898
Sortino Ratio Rank
CDNA Omega Ratio Rank: 9797
Omega Ratio Rank
CDNA Calmar Ratio Rank: 9999
Calmar Ratio Rank
CDNA Martin Ratio Rank: 9999
Martin Ratio Rank
The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

VCYT vs. CDNA - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Veracyte, Inc. (VCYT) and CareDx, Inc (CDNA). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.


VCYTCDNADifference
Sharpe ratioReturn per unit of total volatility

-2.08

Sortino ratioReturn per unit of downside risk

-2.20

Omega ratioGain probability vs. loss probability

1.32

1.54

-0.22

Calmar ratioReturn relative to maximum drawdown

2.49

10.90

-8.41

Martin ratioReturn relative to average drawdown

5.48

32.58

-27.10

VCYT vs. CDNA - Sharpe Ratio Comparison

The current VCYT Sharpe Ratio is 1.50, which is lower than the CDNA Sharpe Ratio of 3.58. The chart below compares the historical Sharpe Ratios of VCYT and CDNA, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.


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Drawdowns

VCYT vs. CDNA - Drawdown Comparison

The maximum VCYT drawdown since its inception was -81.19%, smaller than the maximum CDNA drawdown of -94.87%. Use the drawdown chart below to compare losses from any high point for VCYT and CDNA.


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Drawdown Indicators


VCYTCDNADifference

Max Drawdown

Largest peak-to-trough decline

-81.19%

-94.87%

+13.68%

Max Drawdown (1Y)

Largest decline over 1 year

-39.23%

-23.64%

-15.59%

Max Drawdown (3Y)

Largest decline over 3 years

-50.09%

-65.96%

+15.87%

Max Drawdown (5Y)

Largest decline over 5 years

-71.54%

-94.19%

+22.65%

Max Drawdown (10Y)

Largest decline over 10 years

-81.19%

-94.87%

+13.68%

Current Drawdown

Current decline from peak

-43.08%

-54.28%

+11.20%

Average Drawdown

Average peak-to-trough decline

-48.14%

-53.87%

+5.73%

Ulcer Index

Depth and duration of drawdowns from previous peaks

17.77%

7.89%

+9.88%

Volatility

VCYT vs. CDNA - Volatility Comparison

The current volatility for Veracyte, Inc. (VCYT) is 29.33%, while CareDx, Inc (CDNA) has a volatility of 35.19%. This indicates that VCYT experiences smaller price fluctuations and is considered to be less risky than CDNA based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


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Volatility by Period


VCYTCDNADifference

Volatility (1M)

Calculated over the trailing 1-month period

29.33%

35.19%

-5.86%

Volatility (6M)

Calculated over the trailing 6-month period

48.25%

53.85%

-5.60%

Volatility (1Y)

Calculated over the trailing 1-year period

65.08%

72.08%

-7.00%

Volatility (5Y)

Calculated over the trailing 5-year period, annualized

64.89%

79.44%

-14.55%

Volatility (10Y)

Calculated over the trailing 10-year period, annualized

62.58%

79.08%

-16.50%

Dividends

VCYT vs. CDNA - Dividend Comparison

Neither VCYT nor CDNA has paid dividends to shareholders.


Tickers have no history of dividend payments

Financials

VCYT vs. CDNA - Financials Comparison

This section allows you to compare key financial metrics between Veracyte, Inc. and CareDx, Inc. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


Values in USD except per share items

VCYT vs. CDNA - Profitability Comparison

The chart below illustrates the profitability comparison between Veracyte, Inc. and CareDx, Inc over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

Gross Margin
Operating Margin
Net Margin
Quarterly
Annual

VCYT - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Aug 2026, Veracyte, Inc. reported a gross profit of 109.13M and revenue of 150.32M. Therefore, the gross margin over that period was 72.6%.

CDNA - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Aug 2026, CareDx, Inc reported a gross profit of 0.00 and revenue of 131.95M. Therefore, the gross margin over that period was 0.0%.

VCYT - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Aug 2026, Veracyte, Inc. reported an operating income of 21.78M and revenue of 150.32M, resulting in an operating margin of 14.5%.

CDNA - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Aug 2026, CareDx, Inc reported an operating income of 113.22M and revenue of 131.95M, resulting in an operating margin of 85.8%.

VCYT - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Aug 2026, Veracyte, Inc. reported a net income of 25.49M and revenue of 150.32M, resulting in a net margin of 17.0%.

CDNA - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Aug 2026, CareDx, Inc reported a net income of 110.64M and revenue of 131.95M, resulting in a net margin of 83.9%.


Frequently Asked Questions


VCYT and CDNA have a correlation of 0.49, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

CDNA has higher volatility (35.19%) compared to VCYT (29.33%). In terms of maximum drawdown, VCYT dropped -81.19% vs CDNA's -94.87%.

CDNA currently has the higher Sharpe Ratio (3.58 vs 1.50), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.

Portfolio Optimizer

Find the right allocation for VCYT and CDNA

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