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CDNA vs. XBI
Performance
Risk-Adjusted Performance
Dividends
Drawdowns
Volatility

Correlation

The correlation between CDNA and XBI is 0.43, which is considered to be moderate. This suggests that the two assets have some degree of positive relationship in their price movements. Moderate correlation can be acceptable for portfolio diversification, offering a balance between risk and potential returns.


-0.50.00.51.00.4

Performance

CDNA vs. XBI - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in CareDx, Inc (CDNA) and SPDR S&P Biotech ETF (XBI). The values are adjusted to include any dividend payments, if applicable.

-40.00%-30.00%-20.00%-10.00%0.00%SeptemberOctoberNovemberDecember2025February
-25.87%
-8.64%
CDNA
XBI

Key characteristics

Sharpe Ratio

CDNA:

2.36

XBI:

-0.01

Sortino Ratio

CDNA:

3.04

XBI:

0.15

Omega Ratio

CDNA:

1.39

XBI:

1.02

Calmar Ratio

CDNA:

2.04

XBI:

-0.01

Martin Ratio

CDNA:

8.47

XBI:

-0.03

Ulcer Index

CDNA:

22.15%

XBI:

9.40%

Daily Std Dev

CDNA:

79.51%

XBI:

24.39%

Max Drawdown

CDNA:

-94.87%

XBI:

-63.89%

Current Drawdown

CDNA:

-75.54%

XBI:

-46.61%

Returns By Period

In the year-to-date period, CDNA achieves a 9.20% return, which is significantly higher than XBI's 2.95% return. Over the past 10 years, CDNA has outperformed XBI with an annualized return of 14.35%, while XBI has yielded a comparatively lower 2.79% annualized return.


CDNA

YTD

9.20%

1M

3.00%

6M

-24.48%

1Y

183.74%

5Y*

-3.73%

10Y*

14.35%

XBI

YTD

2.95%

1M

2.44%

6M

-7.39%

1Y

0.41%

5Y*

-0.87%

10Y*

2.79%

*Annualized

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Risk-Adjusted Performance

CDNA vs. XBI — Risk-Adjusted Performance Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

CDNA
The Risk-Adjusted Performance Rank of CDNA is 9191
Overall Rank
The Sharpe Ratio Rank of CDNA is 9595
Sharpe Ratio Rank
The Sortino Ratio Rank of CDNA is 9191
Sortino Ratio Rank
The Omega Ratio Rank of CDNA is 9090
Omega Ratio Rank
The Calmar Ratio Rank of CDNA is 9090
Calmar Ratio Rank
The Martin Ratio Rank of CDNA is 8989
Martin Ratio Rank

XBI
The Risk-Adjusted Performance Rank of XBI is 77
Overall Rank
The Sharpe Ratio Rank of XBI is 77
Sharpe Ratio Rank
The Sortino Ratio Rank of XBI is 77
Sortino Ratio Rank
The Omega Ratio Rank of XBI is 77
Omega Ratio Rank
The Calmar Ratio Rank of XBI is 77
Calmar Ratio Rank
The Martin Ratio Rank of XBI is 77
Martin Ratio Rank
The risk-adjusted ranks indicate the investment's position relative to the market. A rank closer to 100 signifies top-performing investments, while a rank closer to 0 might suggest underperformance, based on the selected ratio. The values are calculated based on the past 12 months of returns.

CDNA vs. XBI - Risk-Adjusted Performance Comparison

This table presents a comparison of risk-adjusted performance metrics for CareDx, Inc (CDNA) and SPDR S&P Biotech ETF (XBI). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.


Sharpe ratio
The chart of Sharpe ratio for CDNA, currently valued at 2.36, compared to the broader market-2.000.002.002.36-0.01
The chart of Sortino ratio for CDNA, currently valued at 3.04, compared to the broader market-4.00-2.000.002.004.006.003.040.15
The chart of Omega ratio for CDNA, currently valued at 1.39, compared to the broader market0.501.001.502.001.391.02
The chart of Calmar ratio for CDNA, currently valued at 2.04, compared to the broader market0.002.004.006.002.04-0.01
The chart of Martin ratio for CDNA, currently valued at 8.47, compared to the broader market-10.000.0010.0020.0030.008.47-0.03
CDNA
XBI

The current CDNA Sharpe Ratio is 2.36, which is higher than the XBI Sharpe Ratio of -0.01. The chart below compares the historical Sharpe Ratios of CDNA and XBI, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.


Rolling 12-month Sharpe Ratio0.001.002.003.004.005.006.00SeptemberOctoberNovemberDecember2025February
2.36
-0.01
CDNA
XBI

Dividends

CDNA vs. XBI - Dividend Comparison

CDNA has not paid dividends to shareholders, while XBI's dividend yield for the trailing twelve months is around 0.14%.


TTM20242023202220212020201920182017201620152014
CDNA
CareDx, Inc
0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%
XBI
SPDR S&P Biotech ETF
0.14%0.15%0.02%0.00%0.04%0.20%0.00%0.28%0.24%0.26%0.61%1.07%

Drawdowns

CDNA vs. XBI - Drawdown Comparison

The maximum CDNA drawdown since its inception was -94.87%, which is greater than XBI's maximum drawdown of -63.89%. Use the drawdown chart below to compare losses from any high point for CDNA and XBI. For additional features, visit the drawdowns tool.


-80.00%-70.00%-60.00%-50.00%-40.00%SeptemberOctoberNovemberDecember2025February
-75.54%
-46.61%
CDNA
XBI

Volatility

CDNA vs. XBI - Volatility Comparison

CareDx, Inc (CDNA) has a higher volatility of 18.28% compared to SPDR S&P Biotech ETF (XBI) at 5.62%. This indicates that CDNA's price experiences larger fluctuations and is considered to be riskier than XBI based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


5.00%10.00%15.00%20.00%25.00%30.00%SeptemberOctoberNovemberDecember2025February
18.28%
5.62%
CDNA
XBI
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Disclaimer

The information contained herein does not constitute investment advice and made available for educational purposes only. Prices and returns on equities are listed without consideration of fees, commissions, taxes, penalties, or interest payable due to purchasing, holding, or selling.

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