CDNA vs. AIOS

Last updated Jun 23, 2026

CDNA (CareDx, Inc) and AIOS (AIOS Tech, Inc.) are both stocks. CDNA operates in Diagnostics & Research (Healthcare), while AIOS operates in Information Technology Services (Technology). Over the past 5 years, CDNA returned -23.19%/yr vs -64.97%/yr for AIOS. At a 0.13 correlation, their price movements are largely independent.

Performance

CDNA vs. AIOS - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in CareDx, Inc (CDNA) and AIOS Tech, Inc. (AIOS). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, CDNA achieves a 32.96% return, which is significantly higher than AIOS's -45.51% return.

CDNA

• 1D: -4.32%
• 1M: 15.81%
• YTD: 32.96%
• 6M: 25.12%
• 1Y: 31.57%
• 3Y*: 47.04%
• 5Y*: -23.19%
• 10Y*: 18.09%

AIOS

• 1D: -13.31%
• 1M: -27.40%
• YTD: -45.51%
• 6M: -59.23%
• 1Y: -82.67%
• 3Y*: -46.37%
• 5Y*: -64.97%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

CDNA vs. AIOS - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
CDNA CareDx, Inc	32.96%	-12.00%	78.42%	5.17%	-74.91%	-37.23%	235.88%	-14.20%	242.51%	171.85%
AIOS AIOS Tech, Inc.	-45.51%	-84.05%	67.75%	-29.78%	-82.26%	-82.37%	213.97%	584.53%	-67.78%	-46.87%

Correlation

The correlation between CDNA and AIOS is 0.23, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.23
Correlation (3Y) Calculated over the trailing 3-year period	0.13
Correlation (5Y) Calculated over the trailing 5-year period	0.17
Correlation (All Time) Calculated using the full available price history since Dec 27, 2016	0.13

Fundamentals

Market Cap CDNA : $1.33B AIOS : $2.70M
EPS CDNA : -$0.15 AIOS : -$955.63
PS Ratio CDNA : 3.22 AIOS : 0.01
PB Ratio CDNA : 4.24 AIOS : 0.58
Total Revenue (TTM) CDNA : $412.82M AIOS : $344.69M
Gross Profit (TTM) CDNA : $198.97M AIOS : $33.75M
EBITDA (TTM) CDNA : $4.15M AIOS : $9.69M

Return for Risk

CDNA vs. AIOS — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

CDNA

CDNA Risk / Return Rank: 59
CDNA Sharpe Ratio Rank: 57
CDNA Sortino Ratio Rank: 57
CDNA Omega Ratio Rank: 63
CDNA Calmar Ratio Rank: 58
CDNA Martin Ratio Rank: 58

AIOS

AIOS Risk / Return Rank: 17
AIOS Sharpe Ratio Rank: 23
AIOS Sortino Ratio Rank: 24
AIOS Omega Ratio Rank: 23
AIOS Calmar Ratio Rank: 6
AIOS Martin Ratio Rank: 9

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

CDNA vs. AIOS - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for CareDx, Inc (CDNA) and AIOS Tech, Inc. (AIOS). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	CDNA	AIOS	Difference
Sharpe ratio: Return per unit of total volatility	0.44	-0.44	+0.88
Sortino ratio: Return per unit of downside risk	1.09	-0.31	+1.40
Omega ratio: Gain probability vs. loss probability	1.17	0.95	+0.22
Calmar ratio: Return relative to maximum drawdown	0.72	-0.91	+1.63
Martin ratio: Return relative to average drawdown	1.50	-1.39	+2.89

CDNA vs. AIOS - Sharpe Ratio Comparison

The current CDNA Sharpe Ratio is 0.44, which is higher than the AIOS Sharpe Ratio of -0.44. The chart below compares the historical Sharpe Ratios of CDNA and AIOS, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

CDNA vs. AIOS - Drawdown Comparison

The maximum CDNA drawdown since its inception was -94.87%, roughly equal to the maximum AIOS drawdown of -99.84%. Use the drawdown chart below to compare losses from any high point for CDNA and AIOS.

Drawdown Indicators

	CDNA	AIOS	Difference
Max Drawdown Largest peak-to-trough decline	-94.87%	-99.84%	+4.97%
Max Drawdown (1Y) Largest decline over 1 year	-43.92%	-91.43%	+47.51%
Max Drawdown (3Y) Largest decline over 3 years	-65.96%	-98.13%	+32.17%
Max Drawdown (5Y) Largest decline over 5 years	-94.85%	-99.76%	+4.91%
Max Drawdown (10Y) Largest decline over 10 years	-94.87%	—	—
Current Drawdown Current decline from peak	-73.80%	-99.76%	+25.96%
Average Drawdown Average peak-to-trough decline	-53.75%	-74.24%	+20.49%
Ulcer Index Depth and duration of drawdowns from previous peaks	21.10%	59.53%	-38.43%

Volatility

CDNA vs. AIOS - Volatility Comparison

The current volatility for CareDx, Inc (CDNA) is 16.23%, while AIOS Tech, Inc. (AIOS) has a volatility of 40.60%. This indicates that CDNA experiences smaller price fluctuations and is considered to be less risky than AIOS based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	CDNA	AIOS	Difference
Volatility (1M) Calculated over the trailing 1-month period	16.23%	40.60%	-24.37%
Volatility (6M) Calculated over the trailing 6-month period	45.88%	161.43%	-115.55%
Volatility (1Y) Calculated over the trailing 1-year period	72.34%	186.76%	-114.42%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	77.50%	126.95%	-49.45%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	78.19%	113.05%	-34.86%

Dividends

CDNA vs. AIOS - Dividend Comparison

Neither CDNA nor AIOS has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both CDNA and AIOS in my portfolio?

CDNA and AIOS have a correlation of 0.23, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, CDNA or AIOS?

AIOS has higher volatility (40.60%) compared to CDNA (16.23%). In terms of maximum drawdown, CDNA dropped -94.87% vs AIOS's -99.84%.

Which has better risk-adjusted returns?

CDNA currently has the higher Sharpe Ratio (0.44 vs -0.44), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.