UUP vs. CURE

Last updated Jun 13, 2026

UUP (Invesco DB US Dollar Index Bullish Fund) and CURE (Direxion Daily Healthcare Bull 3x Shares) are both exchange-traded funds - UUP is a Currency fund tracking the Deutsche Bank Long US Dollar Index (USDX) Futures Index, while CURE is a Leveraged Equities fund tracking the Health Care Select Sector Index (300%). Both are passively managed. Over the past 10 years, UUP returned 3.13%/yr vs 13.49%/yr for CURE. At a correlation of -0.14, they often move in opposite directions. UUP charges 0.75%/yr vs 1.08%/yr for CURE.

Performance

UUP vs. CURE - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Invesco DB US Dollar Index Bullish Fund (UUP) and Direxion Daily Healthcare Bull 3x Shares (CURE). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, UUP achieves a 3.40% return, which is significantly higher than CURE's -7.96% return. Over the past 10 years, UUP has underperformed CURE with an annualized return of 3.13%, while CURE has yielded a comparatively higher 13.49% annualized return.

UUP

• 1D: 0.00%
• 1M: 1.60%
• YTD: 3.40%
• 6M: 3.41%
• 1Y: 6.66%
• 3Y*: 4.21%
• 5Y*: 5.89%
• 10Y*: 3.13%

CURE

• 1D: -0.55%
• 1M: 13.53%
• YTD: -7.96%
• 6M: -6.00%
• 1Y: 26.46%
• 3Y*: 3.05%
• 5Y*: 1.51%
• 10Y*: 13.49%

*Multi-year figures are annualized to reflect compound growth (CAGR)

UUP vs. CURE - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
UUP Invesco DB US Dollar Index Bullish Fund	3.40%	-4.99%	13.50%	3.63%	9.46%	5.73%	-6.66%	4.09%	7.05%	-9.10%
CURE Direxion Daily Healthcare Bull 3x Shares	-7.96%	22.55%	-8.47%	-9.40%	-20.51%	88.30%	5.02%	55.66%	2.82%	69.32%

Correlation

The correlation between UUP and CURE is -0.24, meaning they tend to move in opposite directions. This is especially valuable for risk management - when one declines, the other has historically tended to hold steady or rise.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	-0.24
Correlation (3Y) Calculated over the trailing 3-year period	-0.18
Correlation (5Y) Calculated over the trailing 5-year period	-0.25
Correlation (10Y) Calculated over the trailing 10-year period	-0.17
Correlation (All Time) Calculated using the full available price history since Jun 15, 2011	-0.14

The correlation between UUP and CURE shifts across timeframes, from -0.25 (5 years) to -0.14 (all time), reflecting how their relationship changes across market environments.

UUP vs. CURE - Sectors Allocation Comparison

Sectors	UUP	CURE
Financial Services	97.4%	-
Basic Materials	-	-
Communication Services	-	-
Consumer Cyclical	-	-
Consumer Defensive	-	-
Energy	-	-
Healthcare	-	100.0%
Industrials	-	-
Real Estate	-	-
Technology	-	-
Utilities	-	-

Return for Risk

UUP vs. CURE — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

UUP

UUP Risk / Return Rank: 36
UUP Sharpe Ratio Rank: 35
UUP Sortino Ratio Rank: 34
UUP Omega Ratio Rank: 33
UUP Calmar Ratio Rank: 42
UUP Martin Ratio Rank: 36

CURE

CURE Risk / Return Rank: 21
CURE Sharpe Ratio Rank: 20
CURE Sortino Ratio Rank: 24
CURE Omega Ratio Rank: 22
CURE Calmar Ratio Rank: 22
CURE Martin Ratio Rank: 19

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

UUP vs. CURE - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Invesco DB US Dollar Index Bullish Fund (UUP) and Direxion Daily Healthcare Bull 3x Shares (CURE). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	UUP	CURE	Difference
Sharpe ratio: Return per unit of total volatility	1.11	0.60	+0.51
Sortino ratio: Return per unit of downside risk	1.60	1.18	+0.41
Omega ratio: Gain probability vs. loss probability	1.20	1.13	+0.07
Calmar ratio: Return relative to maximum drawdown	1.83	0.85	+0.98
Martin ratio: Return relative to average drawdown	4.89	1.94	+2.95

UUP vs. CURE - Sharpe Ratio Comparison

The current UUP Sharpe Ratio is 1.11, which is higher than the CURE Sharpe Ratio of 0.60. The chart below compares the historical Sharpe Ratios of UUP and CURE, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

UUP vs. CURE - Drawdown Comparison

The maximum UUP drawdown since its inception was -22.19%, smaller than the maximum CURE drawdown of -69.19%. Use the drawdown chart below to compare losses from any high point for UUP and CURE.

Drawdown Indicators

	UUP	CURE	Difference
Max Drawdown Largest peak-to-trough decline	-22.19%	-69.19%	+47.00%
Max Drawdown (1Y) Largest decline over 1 year	-3.65%	-31.10%	+27.45%
Max Drawdown (3Y) Largest decline over 3 years	-10.05%	-51.93%	+41.88%
Max Drawdown (5Y) Largest decline over 5 years	-10.37%	-52.23%	+41.86%
Max Drawdown (10Y) Largest decline over 10 years	-14.24%	-69.19%	+54.95%
Current Drawdown Current decline from peak	-3.17%	-26.94%	+23.77%
Average Drawdown Average peak-to-trough decline	-8.91%	-18.16%	+9.25%
Ulcer Index Depth and duration of drawdowns from previous peaks	1.36%	13.71%	-12.35%

Volatility

UUP vs. CURE - Volatility Comparison

The current volatility for Invesco DB US Dollar Index Bullish Fund (UUP) is 1.24%, while Direxion Daily Healthcare Bull 3x Shares (CURE) has a volatility of 14.30%. This indicates that UUP experiences smaller price fluctuations and is considered to be less risky than CURE based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	UUP	CURE	Difference
Volatility (1M) Calculated over the trailing 1-month period	1.24%	14.30%	-13.06%
Volatility (6M) Calculated over the trailing 6-month period	4.23%	30.87%	-26.64%
Volatility (1Y) Calculated over the trailing 1-year period	6.07%	44.32%	-38.25%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	7.22%	43.84%	-36.62%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	6.96%	49.59%	-42.63%

UUP vs. CURE - Expense Ratio Comparison

UUP has a 0.75% expense ratio, which is lower than CURE's 1.08% expense ratio.

Dividends

UUP vs. CURE - Dividend Comparison

UUP's dividend yield for the trailing twelve months is around 3.32%, more than CURE's 1.16% yield.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017
CURE Direxion Daily Healthcare Bull 3x Shares	1.16%	1.12%	1.17%	2.02%	0.38%	0.02%	0.17%	0.40%	0.70%	0.18%
UUP Invesco DB US Dollar Index Bullish Fund	3.32%	3.43%	4.48%	6.44%	0.89%	0.00%	0.00%	2.03%	1.08%	0.10%

Frequently Asked Questions

Can I hold both UUP and CURE in my portfolio?

UUP and CURE have a correlation of -0.24, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, UUP or CURE?

CURE has higher volatility (14.30%) compared to UUP (1.24%). In terms of maximum drawdown, UUP dropped -22.19% vs CURE's -69.19%.

Which ETF is better, UUP or CURE?

On 10-year performance, CURE leads with 13.49% vs 3.13% for UUP. On fees, UUP is cheaper at 0.75% per year. On volatility, UUP has been the lower-risk option at 1.24%. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF has performed better, UUP or CURE?

Over the 10-year period, CURE has performed better with a 13.49% return vs 3.13%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.

Which ETF is cheaper, UUP or CURE?

UUP is cheaper with a 0.75% expense ratio, compared with 1.08% for CURE.

Which ETF pays a higher dividend yield, UUP or CURE?

UUP has the higher dividend yield at 3.32%, compared with 1.16% for CURE.

What is the main difference between UUP and CURE?

UUP is categorized as Currency, while CURE is Leveraged Equities. UUP tracks Deutsche Bank Long US Dollar Index (USDX) Futures Index, while CURE tracks Health Care Select Sector Index (300%). They also come from different issuers: Invesco and Direxion. Their fees differ too: 0.75% for UUP and 1.08% for CURE.

Which has better risk-adjusted returns?

UUP currently has the higher Sharpe Ratio (1.11 vs 0.60), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.