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TWST vs. CRSP
Performance
Risk-Adjusted Performance
Dividends
Drawdowns
Volatility
Financials

Correlation

The correlation between TWST and CRSP is 0.55, which is considered to be moderate. This suggests that the two assets have some degree of positive relationship in their price movements. Moderate correlation can be acceptable for portfolio diversification, offering a balance between risk and potential returns.


-0.50.00.51.00.6

Performance

TWST vs. CRSP - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Twist Bioscience Corporation (TWST) and CRISPR Therapeutics AG (CRSP). The values are adjusted to include any dividend payments, if applicable.

-30.00%-20.00%-10.00%0.00%10.00%AugustSeptemberOctoberNovemberDecember2025
-14.90%
-26.13%
TWST
CRSP

Key characteristics

Sharpe Ratio

TWST:

0.43

CRSP:

-0.73

Sortino Ratio

TWST:

1.17

CRSP:

-0.96

Omega Ratio

TWST:

1.13

CRSP:

0.90

Calmar Ratio

TWST:

0.35

CRSP:

-0.45

Martin Ratio

TWST:

1.57

CRSP:

-0.94

Ulcer Index

TWST:

19.08%

CRSP:

38.70%

Daily Std Dev

TWST:

69.63%

CRSP:

50.09%

Max Drawdown

TWST:

-94.48%

CRSP:

-81.74%

Current Drawdown

TWST:

-77.94%

CRSP:

-80.81%

Fundamentals

Market Cap

TWST:

$2.71B

CRSP:

$3.33B

EPS

TWST:

-$3.60

CRSP:

-$2.79

Total Revenue (TTM)

TWST:

$241.48M

CRSP:

$1.62M

Gross Profit (TTM)

TWST:

$104.39M

CRSP:

-$118.31M

EBITDA (TTM)

TWST:

-$141.99M

CRSP:

-$387.56M

Returns By Period

In the year-to-date period, TWST achieves a -1.29% return, which is significantly lower than CRSP's 2.39% return.


TWST

YTD

-1.29%

1M

-5.23%

6M

-14.36%

1Y

31.66%

5Y*

15.12%

10Y*

N/A

CRSP

YTD

2.39%

1M

-9.70%

6M

-28.30%

1Y

-33.78%

5Y*

-7.15%

10Y*

N/A

*Annualized

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Risk-Adjusted Performance

TWST vs. CRSP — Risk-Adjusted Performance Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

TWST
The Risk-Adjusted Performance Rank of TWST is 6262
Overall Rank
The Sharpe Ratio Rank of TWST is 6363
Sharpe Ratio Rank
The Sortino Ratio Rank of TWST is 6565
Sortino Ratio Rank
The Omega Ratio Rank of TWST is 6060
Omega Ratio Rank
The Calmar Ratio Rank of TWST is 6262
Calmar Ratio Rank
The Martin Ratio Rank of TWST is 6363
Martin Ratio Rank

CRSP
The Risk-Adjusted Performance Rank of CRSP is 1717
Overall Rank
The Sharpe Ratio Rank of CRSP is 1111
Sharpe Ratio Rank
The Sortino Ratio Rank of CRSP is 1212
Sortino Ratio Rank
The Omega Ratio Rank of CRSP is 1515
Omega Ratio Rank
The Calmar Ratio Rank of CRSP is 2121
Calmar Ratio Rank
The Martin Ratio Rank of CRSP is 2626
Martin Ratio Rank
The risk-adjusted ranks indicate the investment's position relative to the market. A rank closer to 100 signifies top-performing investments, while a rank closer to 0 might suggest underperformance, based on the selected ratio. The values are calculated based on the past 12 months of returns.

TWST vs. CRSP - Risk-Adjusted Performance Comparison

This table presents a comparison of risk-adjusted performance metrics for Twist Bioscience Corporation (TWST) and CRISPR Therapeutics AG (CRSP). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.


Sharpe ratio
The chart of Sharpe ratio for TWST, currently valued at 0.43, compared to the broader market-2.000.002.004.000.43-0.73
The chart of Sortino ratio for TWST, currently valued at 1.17, compared to the broader market-4.00-2.000.002.004.001.17-0.96
The chart of Omega ratio for TWST, currently valued at 1.13, compared to the broader market0.501.001.502.001.130.90
The chart of Calmar ratio for TWST, currently valued at 0.35, compared to the broader market0.002.004.006.000.35-0.45
The chart of Martin ratio for TWST, currently valued at 1.57, compared to the broader market-10.000.0010.0020.0030.001.57-0.94
TWST
CRSP

The current TWST Sharpe Ratio is 0.43, which is higher than the CRSP Sharpe Ratio of -0.73. The chart below compares the historical Sharpe Ratios of TWST and CRSP, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.


Rolling 12-month Sharpe Ratio-1.00-0.500.000.501.001.502.002.50AugustSeptemberOctoberNovemberDecember2025
0.43
-0.73
TWST
CRSP

Dividends

TWST vs. CRSP - Dividend Comparison

Neither TWST nor CRSP has paid dividends to shareholders.


Tickers have no history of dividend payments

Drawdowns

TWST vs. CRSP - Drawdown Comparison

The maximum TWST drawdown since its inception was -94.48%, which is greater than CRSP's maximum drawdown of -81.74%. Use the drawdown chart below to compare losses from any high point for TWST and CRSP. For additional features, visit the drawdowns tool.


-82.00%-80.00%-78.00%-76.00%-74.00%-72.00%AugustSeptemberOctoberNovemberDecember2025
-77.94%
-80.81%
TWST
CRSP

Volatility

TWST vs. CRSP - Volatility Comparison

Twist Bioscience Corporation (TWST) has a higher volatility of 17.84% compared to CRISPR Therapeutics AG (CRSP) at 13.47%. This indicates that TWST's price experiences larger fluctuations and is considered to be riskier than CRSP based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


10.00%15.00%20.00%25.00%AugustSeptemberOctoberNovemberDecember2025
17.84%
13.47%
TWST
CRSP

Financials

TWST vs. CRSP - Financials Comparison

This section allows you to compare key financial metrics between Twist Bioscience Corporation and CRISPR Therapeutics AG. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


Values in USD except per share items
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Disclaimer

The information contained herein does not constitute investment advice and made available for educational purposes only. Prices and returns on equities are listed without consideration of fees, commissions, taxes, penalties, or interest payable due to purchasing, holding, or selling.

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