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Twist Bioscience Corporation (TWST)
Performance
Risk-Adjusted Performance
Dividends
Drawdowns
Volatility
Financials

Company Info

ISIN

US90184D1000

CUSIP

90184D100

IPO Date

Oct 31, 2018

Highlights

Market Cap

$2.34B

EPS (TTM)

-$3.38

Total Revenue (TTM)

$347.68M

Gross Profit (TTM)

$162.37M

EBITDA (TTM)

-$176.51M

Year Range

$30.72 - $60.90

Target Price

$50.74

Short %

18.43%

Short Ratio

7.71

Share Price Chart


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Compare to other instruments

Search for stocks, ETFs, and funds for a quick comparison or use the comparison tool for more options.


Performance

Performance Chart

The chart shows the growth of an initial investment of $10,000 in Twist Bioscience Corporation, comparing it to the performance of the S&P 500 index or another benchmark. All prices have been adjusted for splits and dividends.


100.00%150.00%200.00%250.00%300.00%December2025FebruaryMarchAprilMay
120.14%
108.72%
TWST (Twist Bioscience Corporation)
Benchmark (^GSPC)

Returns By Period

Twist Bioscience Corporation (TWST) returned -33.68% year-to-date (YTD) and -28.66% over the past 12 months.


TWST

YTD

-33.68%

1M

-23.47%

6M

-32.11%

1Y

-28.66%

5Y*

-4.67%

10Y*

N/A

^GSPC (Benchmark)

YTD

-3.77%

1M

3.72%

6M

-5.60%

1Y

8.55%

5Y*

14.11%

10Y*

10.45%

*Annualized

Monthly Returns

The table below presents the monthly returns of TWST, with color gradation from worst to best to easily spot seasonal factors. Returns are adjusted for dividends.


JanFebMarAprMayJunJulAugSepOctNovDecTotal
202512.70%-25.87%1.13%-2.39%-19.57%-33.68%
2024-12.10%21.27%-12.67%-8.98%34.17%17.61%13.25%-22.52%4.49%-10.67%21.85%-5.51%26.07%
202320.50%-32.17%-22.51%-17.24%21.39%35.05%18.96%-9.65%-7.87%-22.21%52.60%53.26%54.81%
2022-23.22%-5.86%-11.73%-41.60%18.03%2.70%25.11%-8.28%-12.16%-6.84%-16.69%-12.94%-69.23%
202116.46%-16.35%-10.01%8.34%-20.03%24.17%-7.65%-8.00%-5.51%11.06%-19.61%-18.96%-45.23%
202018.29%23.27%-0.13%6.97%16.02%19.37%23.71%24.79%8.64%0.88%45.80%26.45%572.81%
20190.17%-5.88%6.48%2.07%9.09%12.40%16.24%-13.91%-17.74%-0.25%0.04%-11.88%-9.05%
201889.00%-12.74%64.93%

Risk-Adjusted Performance

Risk-Adjusted Performance Rank

The current rank of TWST is 28, indicating average performance compared to other stocks on our website. Here’s a breakdown of how it compares using common performance measures.


The Risk-Adjusted Performance Rank of TWST is 2828
Overall Rank
The Sharpe Ratio Rank of TWST is 2828
Sharpe Ratio Rank
The Sortino Ratio Rank of TWST is 3131
Sortino Ratio Rank
The Omega Ratio Rank of TWST is 3131
Omega Ratio Rank
The Calmar Ratio Rank of TWST is 3131
Calmar Ratio Rank
The Martin Ratio Rank of TWST is 1919
Martin Ratio Rank
The risk-adjusted ranks indicate the investment's position relative to the market. A rank closer to 100 signifies top-performing investments, while a rank closer to 0 might suggest underperformance, based on the selected ratio. The values are calculated based on the past 12 months of returns.

Risk-Adjusted Performance Indicators

The charts below present risk-adjusted performance metrics for Twist Bioscience Corporation (TWST) and compare them to a chosen benchmark (^GSPC). These indicators evaluate an investment's returns against its associated risks.


The Sharpe ratio helps investors understand how much return they're getting for the level of risk taken. A higher Sharpe ratio indicates better risk-adjusted performance, meaning more reward for each unit of risk.

Twist Bioscience Corporation Sharpe ratios as of May 10, 2025 (values are recalculated daily):

  • 1-Year: -0.43
  • 5-Year: -0.06
  • All Time: 0.16

These values reflect how efficiently the investment has delivered returns relative to its volatility over different time periods. All figures are annualized and based on daily total returns (including price changes and dividends).

The chart below shows the rolling Sharpe ratio of Twist Bioscience Corporation compared to the selected benchmark. This view highlights how the investment's risk-adjusted performance has changed over time. For deeper analysis or to customize the calculation, use the Sharpe ratio tool.


Rolling 12-month Sharpe Ratio0.001.002.003.00December2025FebruaryMarchAprilMay
-0.43
0.44
TWST (Twist Bioscience Corporation)
Benchmark (^GSPC)

Dividends

Dividend History


Twist Bioscience Corporation doesn't pay dividends

Drawdowns

Drawdowns Chart

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.


-80.00%-60.00%-40.00%-20.00%0.00%December2025FebruaryMarchAprilMay
-85.18%
-7.88%
TWST (Twist Bioscience Corporation)
Benchmark (^GSPC)

Worst Drawdowns

The table below displays the maximum drawdowns of the Twist Bioscience Corporation. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the Twist Bioscience Corporation was 94.48%, occurring on May 2, 2023. The portfolio has not yet recovered.

The current Twist Bioscience Corporation drawdown is 85.18%.


Depth

Start

To Bottom

Bottom

To Recover

End

Total

-94.48%Jan 21, 2021574May 2, 2023
-47.55%Dec 7, 201811Dec 21, 201882Apr 23, 201993
-43.93%Mar 9, 20208Mar 18, 202034May 6, 202042
-38.66%Jul 31, 2019108Jan 2, 202044Mar 6, 2020152
-34.52%Apr 25, 20199May 7, 201957Jul 29, 201966

Volatility

Volatility Chart

The current Twist Bioscience Corporation volatility is 22.46%, representing the average percentage change in the investments's value, either up or down over the past month. The chart below shows the rolling one-month volatility.


0.00%5.00%10.00%15.00%20.00%25.00%December2025FebruaryMarchAprilMay
22.46%
6.82%
TWST (Twist Bioscience Corporation)
Benchmark (^GSPC)

Financials

Financial Performance

The chart below illustrates the trends in the financial health of Twist Bioscience Corporation over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.


Annual
Quarterly

0.0

Earnings Per Share

The chart presents the Earnings Per Share (EPS) performance of Twist Bioscience Corporation, comparing actual results with analytics estimates. The company has exceeded analyst expectations for EPS in the past quarter, achieving a 16.5% positive surprise.


-1.40-1.20-1.00-0.80-0.6020212022202320242025
-0.66
-0.64
Actual
Estimate

Valuation

The Valuation section provides an overview of how Twist Bioscience Corporation is priced in the market compared to other companies in the Diagnostics & Research industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.


PS Ratio

This chart shows the Price-to-Sales (P/S) ratio for TWST relative to other companies in the Diagnostics & Research industry. Currently, TWST has a P/S ratio of 6.5. This P/S ratio is high relative to other companies in the industry. It could mean the stock is overvalued, or that investors expect strong future growth and profitability.

PB Ratio

The chart illustrates the Price-to-Book (P/B) ratio for TWST in comparison with other companies in the Diagnostics & Research industry. Currently, TWST has a P/B value of 5.1. This P/B ratio is higher than most companies in the industry. It may suggest the stock is overvalued or that investors expect the company to generate high returns on its assets.

Income Statement



TTM
Revenue

Total Revenue

Cost Of Revenue

Gross Profit

Operating Expenses

Selling, General & Admin Expenses

R&D Expenses

Depreciation And Amortization

Total Operating Expenses

Income

Income Before Tax

Operating Income

EBITDA

EBIT

Earnings From Continuing Operations

Net Income

Income Tax Expense

Other Non-Operating Income (Expenses)

Extraordinary Items

Discontinued Operations

Effect Of Accounting Charges

Non Recurring

Minority Interest

Other Items

Interest Income

Interest Expense

Net Interest Income

Values in undefined except per share items