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CRISPR Therapeutics AG (CRSP)
Performance
Return for Risk
Dividends
Drawdowns
Volatility
Financials

Company Info

ISIN
CH0334081137
IPO Date
Oct 19, 2016

Highlights

EPS (TTM)
-$5.47
Total Revenue (TTM)
$36.75M
Gross Profit (TTM)
-$130.60M
EBITDA (TTM)
-$529.50M
Year Range
$30.04 - $78.48
Target Price
$71.00
ROA (TTM)
-21.56%
ROE (TTM)
-25.41%

Share Price Chart


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Performance

Performance Chart

The chart shows the growth of an initial investment of $10,000 in CRISPR Therapeutics AG, comparing it to the performance of the S&P 500 index or another benchmark. All prices have been adjusted for splits and dividends.


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S&P 500 Index

Returns By Period

CRISPR Therapeutics AG (CRSP) has returned -9.29% so far this year and 39.79% over the past 12 months.


CRISPR Therapeutics AG

1D
7.28%
1M
-20.90%
YTD
-9.29%
6M
-26.60%
1Y
39.79%
3Y*
1.70%
5Y*
-16.81%
10Y*

Benchmark (S&P 500 Index)

1D
2.91%
1M
-5.09%
YTD
-4.63%
6M
-2.39%
1Y
16.33%
3Y*
16.69%
5Y*
10.18%
10Y*
12.16%
*Multi-year figures are annualized to reflect compound growth (CAGR)

Monthly Returns

Based on dividend-adjusted daily data since Oct 19, 2016, CRSP's average daily return is +0.13%, while the average monthly return is +2.84%. At this rate, your investment would double in approximately 2.1 years.

Historically, 52% of months were positive and 48% were negative. The best month was Nov 2023 with a return of +71.4%, while the worst month was Oct 2018 at -26.1%. The longest winning streak lasted 5 consecutive months, and the longest losing streak was 6 months.

On a daily basis, CRSP closed higher 49% of trading days. The best single day was Feb 25, 2019 with a return of +25.2%, while the worst single day was Dec 21, 2018 at -17.1%.


JanFebMarAprMayJunJulAugSepOctNovDecTotal
2026-4.73%20.38%-20.90%-9.29%
20255.67%5.60%-22.52%13.64%-6.15%34.03%15.67%-7.87%25.04%-1.27%-16.44%-1.93%33.23%
20240.56%33.79%-19.07%-22.26%1.42%0.50%6.07%-16.70%-1.55%-1.26%10.30%-23.08%-37.12%
202325.51%-3.33%-8.29%8.20%30.85%-12.34%2.12%-12.77%-9.24%-14.23%71.41%-6.19%54.00%
2022-15.87%-3.73%2.28%-20.95%16.99%4.69%23.42%-13.21%0.40%-19.91%4.68%-25.81%-46.36%
20218.22%-24.15%-3.06%7.73%-9.97%36.99%-25.25%3.25%-10.42%-18.40%-12.52%-5.16%-50.51%

Benchmark Metrics

CRISPR Therapeutics AG has an annualized alpha of 16.16%, beta of 1.36, and R² of 0.15 versus S&P 500 Index. Calculated based on daily prices since October 20, 2016.

  • This stock captured 182.39% of S&P 500 Index gains and 159.73% of its losses — amplifying both gains and losses, but participating more in upside than downside.
  • R² of 0.15 means this stock moves largely independently of S&P 500 Index — capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.

Alpha
16.16%
Beta
1.36
0.15
Upside Capture
182.39%
Downside Capture
159.73%

Return for Risk

Risk / Return Rank

CRSP ranks 59 for risk / return — on par with similar stocks. You're getting a typical balance of risk and reward. Not a standout, but not a red flag either — a reasonable choice if other factors align with your goals.


CRSP Risk / Return Rank: 5959
Overall Rank
CRSP Sharpe Ratio Rank: 6363
Sharpe Ratio Rank
CRSP Sortino Ratio Rank: 6464
Sortino Ratio Rank
CRSP Omega Ratio Rank: 5959
Omega Ratio Rank
CRSP Calmar Ratio Rank: 5656
Calmar Ratio Rank
CRSP Martin Ratio Rank: 5555
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

Return / Risk — by metrics

The table below present risk-adjusted performance metrics for CRISPR Therapeutics AG (CRSP) and compare them to a chosen benchmark (S&P 500 Index).


CRSPBenchmarkDifference

Sharpe ratio

Return per unit of total volatility

0.63

0.90

-0.27

Sortino ratio

Return per unit of downside risk

1.36

1.39

-0.02

Omega ratio

Gain probability vs. loss probability

1.16

1.21

-0.05

Calmar ratio

Return relative to maximum drawdown

0.68

1.40

-0.72

Martin ratio

Return relative to average drawdown

1.35

6.61

-5.26

Explore CRSP risk-adjusted metrics in detail

Dive deeper into individual metrics with historical trends, benchmark comparisons, and performance across different time periods.

Dividends

Dividend History


CRISPR Therapeutics AG doesn't pay dividends

Drawdowns

Drawdowns Chart

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.


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Worst Drawdowns

The table below displays the maximum drawdowns of the CRISPR Therapeutics AG. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the CRISPR Therapeutics AG was 85.11%, occurring on Apr 8, 2025. The portfolio has not yet recovered.

The current CRISPR Therapeutics AG drawdown is 77.35%.


Depth

Start

To Bottom

Bottom

To Recover

End

Total

-85.11%Jan 15, 20211062Apr 8, 2025
-69.11%May 31, 2018143Dec 21, 2018377Jun 23, 2020520
-42.6%Mar 1, 201764May 31, 2017149Jan 2, 2018213
-37.24%Jan 5, 201725Feb 9, 201712Feb 28, 201737
-26.73%Mar 15, 201813Apr 3, 201832May 17, 201845

Volatility

Volatility Chart

The chart below shows the rolling one-month volatility.


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Financials

Financial Performance

The chart below illustrates the trends in the financial health of CRISPR Therapeutics AG over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.


Annual
Quarterly

0.0

Valuation

The Valuation section provides an overview of how CRISPR Therapeutics AG is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.


PS Ratio

This chart shows the Price-to-Sales (P/S) ratio for CRSP relative to other companies in the Biotechnology industry. Currently, CRSP has a P/S ratio of 115.4. This P/S ratio is high relative to other companies in the industry. It could mean the stock is overvalued, or that investors expect strong future growth and profitability.

Income Statement



TTM
Revenue

Total Revenue

Cost Of Revenue

Gross Profit

Operating Expenses

Selling, General & Admin Expenses

R&D Expenses

Depreciation And Amortization

Total Operating Expenses

Income

Income Before Tax

Operating Income

EBITDA

EBIT

Earnings From Continuing Operations

Net Income

Income Tax Expense

Other Non-Operating Income (Expenses)

Extraordinary Items

Discontinued Operations

Effect Of Accounting Charges

Non Recurring

Minority Interest

Other Items

Interest Income

Interest Expense

Net Interest Income

Values in undefined except per share items