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TWST vs. SPXL
Performance
Risk-Adjusted Performance
Dividends
Drawdowns
Volatility

Correlation

The correlation between TWST and SPXL is 0.48, which is considered to be moderate. This suggests that the two assets have some degree of positive relationship in their price movements. Moderate correlation can be acceptable for portfolio diversification, offering a balance between risk and potential returns.


Performance

TWST vs. SPXL - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Twist Bioscience Corporation (TWST) and Direxion Daily S&P 500 Bull 3X Shares (SPXL). The values are adjusted to include any dividend payments, if applicable.

150.00%200.00%250.00%300.00%350.00%December2025FebruaryMarchAprilMay
120.14%
227.96%
TWST
SPXL

Key characteristics

Sharpe Ratio

TWST:

-0.43

SPXL:

0.09

Sortino Ratio

TWST:

-0.24

SPXL:

0.56

Omega Ratio

TWST:

0.97

SPXL:

1.08

Calmar Ratio

TWST:

-0.34

SPXL:

0.14

Martin Ratio

TWST:

-1.20

SPXL:

0.45

Ulcer Index

TWST:

23.76%

SPXL:

14.88%

Daily Std Dev

TWST:

67.17%

SPXL:

57.02%

Max Drawdown

TWST:

-94.48%

SPXL:

-76.86%

Current Drawdown

TWST:

-85.18%

SPXL:

-28.55%

Returns By Period

In the year-to-date period, TWST achieves a -33.68% return, which is significantly lower than SPXL's -20.00% return.


TWST

YTD

-33.68%

1M

-23.47%

6M

-32.11%

1Y

-28.66%

5Y*

-4.67%

10Y*

N/A

SPXL

YTD

-20.00%

1M

9.72%

6M

-25.81%

1Y

5.10%

5Y*

30.78%

10Y*

20.37%

*Annualized

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Risk-Adjusted Performance

TWST vs. SPXL — Risk-Adjusted Performance Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

TWST
The Risk-Adjusted Performance Rank of TWST is 2828
Overall Rank
The Sharpe Ratio Rank of TWST is 2828
Sharpe Ratio Rank
The Sortino Ratio Rank of TWST is 3131
Sortino Ratio Rank
The Omega Ratio Rank of TWST is 3131
Omega Ratio Rank
The Calmar Ratio Rank of TWST is 3131
Calmar Ratio Rank
The Martin Ratio Rank of TWST is 1919
Martin Ratio Rank

SPXL
The Risk-Adjusted Performance Rank of SPXL is 3333
Overall Rank
The Sharpe Ratio Rank of SPXL is 2323
Sharpe Ratio Rank
The Sortino Ratio Rank of SPXL is 4242
Sortino Ratio Rank
The Omega Ratio Rank of SPXL is 4343
Omega Ratio Rank
The Calmar Ratio Rank of SPXL is 3030
Calmar Ratio Rank
The Martin Ratio Rank of SPXL is 2828
Martin Ratio Rank
The risk-adjusted ranks indicate the investment's position relative to the market. A rank closer to 100 signifies top-performing investments, while a rank closer to 0 might suggest underperformance, based on the selected ratio. The values are calculated based on the past 12 months of returns.

TWST vs. SPXL - Risk-Adjusted Performance Comparison

This table presents a comparison of risk-adjusted performance metrics for Twist Bioscience Corporation (TWST) and Direxion Daily S&P 500 Bull 3X Shares (SPXL). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.


The current TWST Sharpe Ratio is -0.43, which is lower than the SPXL Sharpe Ratio of 0.09. The chart below compares the historical Sharpe Ratios of TWST and SPXL, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.


Rolling 12-month Sharpe Ratio-1.000.001.002.003.004.00December2025FebruaryMarchAprilMay
-0.43
0.09
TWST
SPXL

Dividends

TWST vs. SPXL - Dividend Comparison

TWST has not paid dividends to shareholders, while SPXL's dividend yield for the trailing twelve months is around 1.00%.


TTM20242023202220212020201920182017
TWST
Twist Bioscience Corporation
0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%
SPXL
Direxion Daily S&P 500 Bull 3X Shares
1.00%0.74%0.98%0.33%0.11%0.22%0.84%1.02%3.88%

Drawdowns

TWST vs. SPXL - Drawdown Comparison

The maximum TWST drawdown since its inception was -94.48%, which is greater than SPXL's maximum drawdown of -76.86%. Use the drawdown chart below to compare losses from any high point for TWST and SPXL. For additional features, visit the drawdowns tool.


-80.00%-60.00%-40.00%-20.00%0.00%December2025FebruaryMarchAprilMay
-85.18%
-28.55%
TWST
SPXL

Volatility

TWST vs. SPXL - Volatility Comparison

Twist Bioscience Corporation (TWST) has a higher volatility of 22.46% compared to Direxion Daily S&P 500 Bull 3X Shares (SPXL) at 20.60%. This indicates that TWST's price experiences larger fluctuations and is considered to be riskier than SPXL based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


10.00%20.00%30.00%40.00%December2025FebruaryMarchAprilMay
22.46%
20.60%
TWST
SPXL