TWST vs. BEAM
TWST (Twist Bioscience Corporation) and BEAM (Beam Therapeutics Inc.) are both stocks. Both are in the Healthcare sector — TWST in Diagnostics & Research, BEAM in Biotechnology. Over the past 5 years, TWST returned -4.20%/yr vs -18.41%/yr for BEAM. A 0.55 correlation means they provide meaningful diversification when combined.
Performance
TWST vs. BEAM - Performance Comparison
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Returns By Period
In the year-to-date period, TWST achieves a 184.84% return, which is significantly higher than BEAM's 11.83% return.
TWST
- 1D
- -0.31%
- 1M
- 18.62%
- 6M
- 137.51%
- YTD
- 184.84%
- 1Y
- 137.58%
- 3Y*
- 57.11%
- 5Y*
- -4.20%
- 10Y*
- —
BEAM
- 1D
- -5.14%
- 1M
- 6.79%
- 6M
- -7.98%
- YTD
- 11.83%
- 1Y
- 46.50%
- 3Y*
- 0.15%
- 5Y*
- -18.41%
- 10Y*
- —
TWST vs. BEAM - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | |
|---|---|---|---|---|---|---|---|
TWST Twist Bioscience Corporation | 184.84% | -31.74% | 26.07% | 54.81% | -69.23% | -45.23% | 428.19% |
BEAM Beam Therapeutics Inc. | 11.83% | 11.77% | -8.89% | -30.40% | -50.92% | -2.39% | 240.17% |
Correlation
The correlation between TWST and BEAM is 0.38, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.38 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.48 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.60 |
Correlation (All Time) Calculated using the full available price history since Feb 6, 2020 | 0.55 |
The correlation between TWST and BEAM shifts across timeframes, from 0.38 (1 year) to 0.60 (5 years), reflecting how their relationship changes across market environments.
Fundamentals
TWST:
$5.63B
BEAM:
$3.19B
TWST:
-$1.33
BEAM:
-$0.63
TWST:
13.47
BEAM:
24.28
TWST:
12.25
BEAM:
2.75
TWST:
$409.48M
BEAM:
$132.27M
TWST:
$213.23M
BEAM:
-$84.92M
TWST:
-$58.23M
BEAM:
-$68.39M
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Return for Risk
TWST vs. BEAM — Risk / Return Rank
TWST
BEAM
TWST vs. BEAM - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Twist Bioscience Corporation (TWST) and Beam Therapeutics Inc. (BEAM). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| TWST | BEAM | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +1.42 | ||
| Sortino ratioReturn per unit of downside risk | +1.16 | ||
| Omega ratioGain probability vs. loss probability | 1.30 | 1.16 | +0.14 |
| Calmar ratioReturn relative to maximum drawdown | 3.84 | 1.22 | +2.61 |
| Martin ratioReturn relative to average drawdown | 8.37 | 2.62 | +5.74 |
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Drawdowns
TWST vs. BEAM - Drawdown Comparison
The maximum TWST drawdown since its inception was -94.48%, which is greater than BEAM's maximum drawdown of -89.12%. Use the drawdown chart below to compare losses from any high point for TWST and BEAM.
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Drawdown Indicators
| TWST | BEAM | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -94.48% | -89.12% | -5.36% |
Max Drawdown (1Y)Largest decline over 1 year | -36.08% | -38.15% | +2.07% |
Max Drawdown (3Y)Largest decline over 3 years | -58.97% | -67.74% | +8.77% |
Max Drawdown (5Y)Largest decline over 5 years | -91.54% | -87.25% | -4.29% |
Current DrawdownCurrent decline from peak | -56.56% | -76.80% | +20.24% |
Average DrawdownAverage peak-to-trough decline | -58.13% | -60.05% | +1.92% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 16.78% | 17.77% | -0.99% |
Volatility
TWST vs. BEAM - Volatility Comparison
Twist Bioscience Corporation (TWST) and Beam Therapeutics Inc. (BEAM) have volatilities of 20.52% and 19.82%, respectively, indicating that both stocks experience similar levels of price fluctuations. This suggests that the risk associated with both stocks, as measured by volatility, is nearly the same. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| TWST | BEAM | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 20.52% | 19.82% | +0.70% |
Volatility (6M)Calculated over the trailing 6-month period | 49.16% | 55.24% | -6.08% |
Volatility (1Y)Calculated over the trailing 1-year period | 67.85% | 75.24% | -7.39% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 76.14% | 75.04% | +1.10% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 78.32% | 80.72% | -2.40% |
Dividends
TWST vs. BEAM - Dividend Comparison
Neither TWST nor BEAM has paid dividends to shareholders.
Financials
TWST vs. BEAM - Financials Comparison
This section allows you to compare key financial metrics between Twist Bioscience Corporation and Beam Therapeutics Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
Frequently Asked Questions
TWST and BEAM have a correlation of 0.38, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
TWST has higher volatility (20.52%) compared to BEAM (19.82%). In terms of maximum drawdown, TWST dropped -94.48% vs BEAM's -89.12%.
TWST currently has the higher Sharpe Ratio (2.04 vs 0.62), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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