SNDX vs. CIFR

Last updated Jun 4, 2026

SNDX (Syndax Pharmaceuticals, Inc.) and CIFR (Cipher Mining Inc.) are both stocks. SNDX operates in Biotechnology (Healthcare), while CIFR operates in Capital Markets (Financial Services). Over the past 3 years, SNDX returned -3.60%/yr vs 116.66%/yr for CIFR. At a 0.22 correlation, their price movements are largely independent.

Performance

SNDX vs. CIFR - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Syndax Pharmaceuticals, Inc. (SNDX) and Cipher Mining Inc. (CIFR). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, SNDX achieves a -12.71% return, which is significantly lower than CIFR's 77.78% return.

SNDX

• 1D: -0.27%
• 1M: -8.12%
• YTD: -12.71%
• 6M: -6.95%
• 1Y: 63.82%
• 3Y*: -3.60%
• 5Y*: 0.54%
• 10Y*: 3.34%

CIFR

• 1D: -0.19%
• 1M: 46.67%
• YTD: 77.78%
• 6M: 40.85%
• 1Y: 663.90%
• 3Y*: 116.66%
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

SNDX vs. CIFR - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021
SNDX Syndax Pharmaceuticals, Inc.	-12.71%	58.93%	-38.82%	-15.09%	16.26%	26.90%
CIFR Cipher Mining Inc.	77.78%	218.10%	12.35%	637.50%	-87.90%	-54.92%

Correlation

The correlation between SNDX and CIFR is 0.10, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.10
Correlation (3Y) Calculated over the trailing 3-year period	0.23
Correlation (All Time) Calculated using the full available price history since Aug 31, 2021	0.22

The correlation between SNDX and CIFR shifts across timeframes, from 0.10 (1 year) to 0.23 (3 years), reflecting how their relationship changes across market environments.

Fundamentals

EPS SNDX : -$3.75 CIFR : -$2.33
PS Ratio SNDX : 5.48 CIFR : 57.66
Total Revenue (TTM) SNDX : $217.17M CIFR : $174.98M
Gross Profit (TTM) SNDX : $208.46M CIFR : -$172.84M
EBITDA (TTM) SNDX : -$171.20M CIFR : -$169.22M

Return for Risk

SNDX vs. CIFR — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

SNDX

SNDX Risk / Return Rank: 75
SNDX Sharpe Ratio Rank: 74
SNDX Sortino Ratio Rank: 75
SNDX Omega Ratio Rank: 69
SNDX Calmar Ratio Rank: 78
SNDX Martin Ratio Rank: 77

CIFR

CIFR Risk / Return Rank: 96
CIFR Sharpe Ratio Rank: 99
CIFR Sortino Ratio Rank: 95
CIFR Omega Ratio Rank: 92
CIFR Calmar Ratio Rank: 98
CIFR Martin Ratio Rank: 97

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

SNDX vs. CIFR - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Syndax Pharmaceuticals, Inc. (SNDX) and Cipher Mining Inc. (CIFR). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	SNDX	CIFR	Difference
Sharpe ratio Return per unit of total volatility	1.12	6.19	-5.07
Sortino ratio Return per unit of downside risk	2.01	4.23	-2.22
Omega ratio Gain probability vs. loss probability	1.22	1.49	-0.27
Calmar ratio Return relative to maximum drawdown	2.37	13.04	-10.67
Martin ratio Return relative to average drawdown	5.73	26.19	-20.46
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

SNDX vs. CIFR - Sharpe Ratio Comparison

The current SNDX Sharpe Ratio is 1.12, which is lower than the CIFR Sharpe Ratio of 6.19. The chart below compares the historical Sharpe Ratios of SNDX and CIFR, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	SNDX	CIFR	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.12	6.19	-5.07
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.01	—	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.05	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	0.06	0.18	-0.12

Drawdowns

SNDX vs. CIFR - Drawdown Comparison

The maximum SNDX drawdown since its inception was -78.98%, smaller than the maximum CIFR drawdown of -97.16%. Use the drawdown chart below to compare losses from any high point for SNDX and CIFR.

Drawdown Indicators

	SNDX	CIFR	Difference
Max Drawdown Largest peak-to-trough decline	-78.98%	-97.16%	+18.18%
Max Drawdown (1Y) Largest decline over 1 year	-27.08%	-51.38%	+24.30%
Max Drawdown (3Y) Largest decline over 3 years	-64.81%	-71.74%	+6.93%
Max Drawdown (5Y) Largest decline over 5 years	-69.88%	—	—
Max Drawdown (10Y) Largest decline over 10 years	-78.98%	—	—
Current Drawdown Current decline from peak	-36.71%	-0.19%	-36.52%
Average Drawdown Average peak-to-trough decline	-35.81%	-66.62%	+30.81%
Ulcer Index Depth and duration of drawdowns from previous peaks	11.16%	25.53%	-14.37%

Volatility

SNDX vs. CIFR - Volatility Comparison

The current volatility for Syndax Pharmaceuticals, Inc. (SNDX) is 11.14%, while Cipher Mining Inc. (CIFR) has a volatility of 31.03%. This indicates that SNDX experiences smaller price fluctuations and is considered to be less risky than CIFR based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	SNDX	CIFR	Difference
Volatility (1M) Calculated over the trailing 1-month period	11.14%	31.03%	-19.89%
Volatility (6M) Calculated over the trailing 6-month period	32.57%	70.59%	-38.02%
Volatility (1Y) Calculated over the trailing 1-year period	57.18%	108.31%	-51.13%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	54.80%	121.98%	-67.18%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	71.17%	121.98%	-50.81%

Dividends

SNDX vs. CIFR - Dividend Comparison

Neither SNDX nor CIFR has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both SNDX and CIFR in my portfolio?

SNDX and CIFR have a correlation of 0.10, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, SNDX or CIFR?

CIFR has higher volatility (31.03%) compared to SNDX (11.14%). In terms of maximum drawdown, SNDX dropped -78.98% vs CIFR's -97.16%.

Which has better risk-adjusted returns?

CIFR currently has the higher Sharpe Ratio (6.19 vs 1.12), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.