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Syndax Pharmaceuticals, Inc. (SNDX)
Performance
Risk-Adjusted Performance
Dividends
Drawdowns
Volatility
Financials

Company Info

ISIN

US87164F1057

CUSIP

87164F105

IPO Date

Mar 3, 2016

Highlights

Market Cap

$1.18B

EPS (TTM)

-$3.72

Total Revenue (TTM)

$43.72M

Gross Profit (TTM)

-$1.50M

EBITDA (TTM)

-$325.24M

Year Range

$9.66 - $25.07

Target Price

$35.25

Short %

27.79%

Short Ratio

11.32

Share Price Chart


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Performance

Performance Chart

The chart shows the growth of an initial investment of $10,000 in Syndax Pharmaceuticals, Inc., comparing it to the performance of the S&P 500 index or another benchmark. All prices have been adjusted for splits and dividends.


0.00%50.00%100.00%150.00%200.00%December2025FebruaryMarchAprilMay
-10.91%
183.93%
SNDX (Syndax Pharmaceuticals, Inc.)
Benchmark (^GSPC)

Returns By Period

Syndax Pharmaceuticals, Inc. (SNDX) returned -19.06% year-to-date (YTD) and -51.30% over the past 12 months.


SNDX

YTD

-19.06%

1M

-7.12%

6M

-50.94%

1Y

-51.30%

5Y*

-9.93%

10Y*

N/A

^GSPC (Benchmark)

YTD

-3.77%

1M

3.72%

6M

-5.60%

1Y

8.55%

5Y*

14.11%

10Y*

10.45%

*Annualized

Monthly Returns

The table below presents the monthly returns of SNDX, with color gradation from worst to best to easily spot seasonal factors. Returns are adjusted for dividends.


JanFebMarAprMayJunJulAugSepOctNovDecTotal
20257.19%10.37%-21.45%15.18%-24.38%-19.06%
2024-5.18%14.40%1.54%-11.22%-8.80%6.54%10.57%-9.47%-6.33%-2.03%-11.35%-20.93%-38.82%
202312.77%-11.67%-16.69%-2.70%-2.82%4.81%1.86%-13.18%-21.56%-3.03%18.22%29.83%-15.09%
2022-25.35%-4.59%11.48%-3.51%-1.61%16.61%5.87%15.91%1.78%-4.45%4.36%6.22%16.26%
2021-9.89%21.81%-8.40%-28.71%15.24%-6.53%-15.08%19.96%9.26%1.78%-17.89%37.07%-1.57%
20206.83%0.32%16.58%64.08%-10.00%-8.52%-4.79%15.59%-9.50%17.95%33.08%-4.01%153.30%
201925.84%10.18%-14.91%36.19%2.10%27.53%3.11%-12.40%-11.18%-10.04%8.48%20.44%97.30%
201824.43%-17.06%57.41%-26.63%-16.38%-19.59%-3.99%15.13%4.12%-40.47%6.03%-12.75%-49.20%
20176.00%49.74%20.56%-30.83%27.92%15.07%-13.31%-4.21%0.86%-4.44%-21.65%0.00%22.18%
201610.91%2.78%0.37%-28.31%26.09%14.17%6.91%-22.10%-18.04%-25.93%-40.30%

Risk-Adjusted Performance

Risk-Adjusted Performance Rank

The current rank of SNDX is 8, meaning it’s performing worse than 92% of other stocks on our website when it comes to balancing risk and reward. Below is a breakdown of how it compares using common performance measures.


The Risk-Adjusted Performance Rank of SNDX is 88
Overall Rank
The Sharpe Ratio Rank of SNDX is 99
Sharpe Ratio Rank
The Sortino Ratio Rank of SNDX is 1010
Sortino Ratio Rank
The Omega Ratio Rank of SNDX is 1010
Omega Ratio Rank
The Calmar Ratio Rank of SNDX is 55
Calmar Ratio Rank
The Martin Ratio Rank of SNDX is 44
Martin Ratio Rank
The risk-adjusted ranks indicate the investment's position relative to the market. A rank closer to 100 signifies top-performing investments, while a rank closer to 0 might suggest underperformance, based on the selected ratio. The values are calculated based on the past 12 months of returns.

Risk-Adjusted Performance Indicators

The charts below present risk-adjusted performance metrics for Syndax Pharmaceuticals, Inc. (SNDX) and compare them to a chosen benchmark (^GSPC). These indicators evaluate an investment's returns against its associated risks.


The Sharpe ratio helps investors understand how much return they're getting for the level of risk taken. A higher Sharpe ratio indicates better risk-adjusted performance, meaning more reward for each unit of risk.

Syndax Pharmaceuticals, Inc. Sharpe ratios as of May 10, 2025 (values are recalculated daily):

  • 1-Year: -0.84
  • 5-Year: -0.17
  • All Time: -0.02

These values reflect how efficiently the investment has delivered returns relative to its volatility over different time periods. All figures are annualized and based on daily total returns (including price changes and dividends).

The chart below shows the rolling Sharpe ratio of Syndax Pharmaceuticals, Inc. compared to the selected benchmark. This view highlights how the investment's risk-adjusted performance has changed over time. For deeper analysis or to customize the calculation, use the Sharpe ratio tool.


Rolling 12-month Sharpe Ratio-1.000.001.002.003.00December2025FebruaryMarchAprilMay
-0.84
0.44
SNDX (Syndax Pharmaceuticals, Inc.)
Benchmark (^GSPC)

Dividends

Dividend History


Syndax Pharmaceuticals, Inc. doesn't pay dividends

Drawdowns

Drawdowns Chart

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.


-70.00%-60.00%-50.00%-40.00%-30.00%-20.00%-10.00%0.00%December2025FebruaryMarchAprilMay
-63.08%
-7.88%
SNDX (Syndax Pharmaceuticals, Inc.)
Benchmark (^GSPC)

Worst Drawdowns

The table below displays the maximum drawdowns of the Syndax Pharmaceuticals, Inc.. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the Syndax Pharmaceuticals, Inc. was 78.98%, occurring on Dec 24, 2018. Recovery took 337 trading sessions.

The current Syndax Pharmaceuticals, Inc. drawdown is 63.08%.


Depth

Start

To Bottom

Bottom

To Recover

End

Total

-78.98%Aug 24, 2016588Dec 24, 2018337Apr 28, 2020925
-65.53%Feb 2, 2023567May 7, 2025
-49.24%Dec 22, 202081Apr 20, 2021437Jan 12, 2023518
-45.42%Apr 7, 201657Jun 27, 201640Aug 23, 201697
-36.18%May 18, 202048Jul 24, 202073Nov 5, 2020121

Volatility

Volatility Chart

The current Syndax Pharmaceuticals, Inc. volatility is 32.04%, representing the average percentage change in the investments's value, either up or down over the past month. The chart below shows the rolling one-month volatility.


0.00%5.00%10.00%15.00%20.00%25.00%30.00%35.00%December2025FebruaryMarchAprilMay
32.04%
6.82%
SNDX (Syndax Pharmaceuticals, Inc.)
Benchmark (^GSPC)

Financials

Financial Performance

The chart below illustrates the trends in the financial health of Syndax Pharmaceuticals, Inc. over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.


Annual
Quarterly

0.0

Earnings Per Share

The chart presents the Earnings Per Share (EPS) performance of Syndax Pharmaceuticals, Inc., comparing actual results with analytics estimates. In the past quarter, the company did not meet analyst expectations for EPS, resulting in a surprise of -380.6%.


-1.50-1.00-0.500.000.501.001.502.0020212022202320242025
-0.98
-0.23
Actual
Estimate

Valuation

The Valuation section provides an overview of how Syndax Pharmaceuticals, Inc. is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.


PEG Ratio

The chart shows the Price/Earnings to Growth (PEG) ratio for SNDX compared to other companies in the Biotechnology industry. SNDX currently has a PEG ratio of 0.0. This PEG ratio is low compared to industry peers, which could indicate the stock is undervalued relative to its expected growth.

PS Ratio

This chart shows the Price-to-Sales (P/S) ratio for SNDX relative to other companies in the Biotechnology industry. Currently, SNDX has a P/S ratio of 49.3. This P/S ratio falls within the average range for the industry, suggesting the stock is fairly valued based on its revenue.

PB Ratio

The chart illustrates the Price-to-Book (P/B) ratio for SNDX in comparison with other companies in the Biotechnology industry. Currently, SNDX has a P/B value of 4.1. This P/B ratio is in line with the industry average, suggesting the stock is valued fairly in relation to its book value.

Income Statement



TTM
Revenue

Total Revenue

Cost Of Revenue

Gross Profit

Operating Expenses

Selling, General & Admin Expenses

R&D Expenses

Depreciation And Amortization

Total Operating Expenses

Income

Income Before Tax

Operating Income

EBITDA

EBIT

Earnings From Continuing Operations

Net Income

Income Tax Expense

Other Non-Operating Income (Expenses)

Extraordinary Items

Discontinued Operations

Effect Of Accounting Charges

Non Recurring

Minority Interest

Other Items

Interest Income

Interest Expense

Net Interest Income

Values in undefined except per share items