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SKYE vs. QURE
Performance
Return for Risk
Drawdowns
Volatility
Dividends
Financials

Performance

SKYE vs. QURE - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Skye Bioscience, Inc (SKYE) and uniQure N.V. (QURE). The values are adjusted to include any dividend payments, if applicable.

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Returns By Period

In the year-to-date period, SKYE achieves a -12.81% return, which is significantly lower than QURE's 65.90% return. Over the past 10 years, SKYE has underperformed QURE with an annualized return of -40.13%, while QURE has yielded a comparatively higher 18.67% annualized return.


SKYE

1D
0.68%
1M
-7.58%
6M
-34.63%
YTD
-12.81%
1Y
-83.20%
3Y*
-54.08%
5Y*
-55.74%
10Y*
-40.13%
ALL TIME*
-48.67%

QURE

1D
-1.37%
1M
-14.24%
6M
73.82%
YTD
65.90%
1Y
164.84%
3Y*
58.24%
5Y*
7.92%
10Y*
18.67%
ALL TIME*
7.05%
*Multi-year figures are annualized to reflect compound growth (CAGR)

SKYE vs. QURE - Yearly Performance Comparison


2026 (YTD)202520242023202220212020201920182017
SKYE
Skye Bioscience, Inc
-12.81%-73.51%4.04%-32.84%-68.85%30.00%-69.47%-67.25%163.16%-49.67%
QURE
uniQure N.V.
65.90%35.50%160.86%-70.14%9.31%-42.60%-49.58%148.65%47.12%249.82%

Correlation

The correlation between SKYE and QURE is 0.17, which is low. Their price movements are largely independent, making them effective diversification partners.


Correlation
Correlation (1Y)
Calculated over the trailing 1-year period

0.17

Correlation (3Y)
Calculated over the trailing 3-year period

0.12

Correlation (5Y)
Calculated over the trailing 5-year period

0.09

Correlation (10Y)
Calculated over the trailing 10-year period

0.06

Correlation (All Time)
Calculated using the full available price history since Apr 2, 2015

0.07

The correlation between SKYE and QURE shifts across timeframes, from 0.06 (10 years) to 0.17 (1 year), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap

SKYE:

$22.97M

QURE:

$2.70B

EPS

SKYE:

-$1.45

QURE:

-$3.51

PB Ratio

SKYE:

2.88

QURE:

16.68

Total Revenue (TTM)

SKYE:

$0.00

QURE:

$18.09M

Gross Profit (TTM)

SKYE:

-$180.01K

QURE:

$13.42M

EBITDA (TTM)

SKYE:

$10.92M

QURE:

-$164.53M

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Return for Risk

SKYE vs. QURE — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

SKYE
SKYE Risk / Return Rank: 1010
Overall Rank
SKYE Sharpe Ratio Rank: 1010
Sharpe Ratio Rank
SKYE Sortino Ratio Rank: 99
Sortino Ratio Rank
SKYE Omega Ratio Rank: 88
Omega Ratio Rank
SKYE Calmar Ratio Rank: 55
Calmar Ratio Rank
SKYE Martin Ratio Rank: 1818
Martin Ratio Rank

QURE
QURE Risk / Return Rank: 8282
Overall Rank
QURE Sharpe Ratio Rank: 6666
Sharpe Ratio Rank
QURE Sortino Ratio Rank: 9696
Sortino Ratio Rank
QURE Omega Ratio Rank: 9797
Omega Ratio Rank
QURE Calmar Ratio Rank: 7878
Calmar Ratio Rank
QURE Martin Ratio Rank: 7171
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

SKYE vs. QURE - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Skye Bioscience, Inc (SKYE) and uniQure N.V. (QURE). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.


SKYEQUREDifference
Sharpe ratioReturn per unit of total volatility

-1.39

Sortino ratioReturn per unit of downside risk

-5.06

Omega ratioGain probability vs. loss probability

0.82

1.55

-0.73

Calmar ratioReturn relative to maximum drawdown

-0.95

1.90

-2.85

Martin ratioReturn relative to average drawdown

-1.17

3.01

-4.17

SKYE vs. QURE - Sharpe Ratio Comparison

The current SKYE Sharpe Ratio is -0.80, which is lower than the QURE Sharpe Ratio of 0.58. The chart below compares the historical Sharpe Ratios of SKYE and QURE, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.


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Drawdowns

SKYE vs. QURE - Drawdown Comparison

The maximum SKYE drawdown since its inception was -99.96%, roughly equal to the maximum QURE drawdown of -95.40%. Use the drawdown chart below to compare losses from any high point for SKYE and QURE.


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Drawdown Indicators


SKYEQUREDifference

Max Drawdown

Largest peak-to-trough decline

-99.96%

-95.40%

-4.56%

Max Drawdown (1Y)

Largest decline over 1 year

-87.85%

-87.21%

-0.64%

Max Drawdown (3Y)

Largest decline over 3 years

-96.79%

-87.21%

-9.58%

Max Drawdown (5Y)

Largest decline over 5 years

-98.56%

-90.11%

-8.45%

Max Drawdown (10Y)

Largest decline over 10 years

-99.83%

-95.40%

-4.43%

Current Drawdown

Current decline from peak

-99.95%

-51.70%

-48.25%

Average Drawdown

Average peak-to-trough decline

-94.97%

-56.54%

-38.43%

Ulcer Index

Depth and duration of drawdowns from previous peaks

71.33%

55.04%

+16.29%

Volatility

SKYE vs. QURE - Volatility Comparison

The current volatility for Skye Bioscience, Inc (SKYE) is 13.30%, while uniQure N.V. (QURE) has a volatility of 17.32%. This indicates that SKYE experiences smaller price fluctuations and is considered to be less risky than QURE based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


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Volatility by Period


SKYEQUREDifference

Volatility (1M)

Calculated over the trailing 1-month period

13.30%

17.32%

-4.02%

Volatility (6M)

Calculated over the trailing 6-month period

54.45%

108.22%

-53.77%

Volatility (1Y)

Calculated over the trailing 1-year period

104.19%

284.69%

-180.50%

Volatility (5Y)

Calculated over the trailing 5-year period, annualized

130.62%

158.18%

-27.56%

Volatility (10Y)

Calculated over the trailing 10-year period, annualized

136.40%

122.35%

+14.05%

Dividends

SKYE vs. QURE - Dividend Comparison

Neither SKYE nor QURE has paid dividends to shareholders.


Tickers have no history of dividend payments

Financials

SKYE vs. QURE - Financials Comparison

This section allows you to compare key financial metrics between Skye Bioscience, Inc and uniQure N.V.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


0.00100.00M200.00M300.00M400.00M500.00MJulyOctober2022AprilJulyOctober2023AprilJulyOctober2024AprilJulyOctober2025AprilJulyOctober20260
3.56M
(SKYE) Total Revenue
(QURE) Total Revenue
Values in USD except per share items

Frequently Asked Questions


SKYE and QURE have a correlation of 0.17, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

QURE has higher volatility (17.32%) compared to SKYE (13.30%). In terms of maximum drawdown, SKYE dropped -99.96% vs QURE's -95.40%.

QURE currently has the higher Sharpe Ratio (0.58 vs -0.80), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.

Portfolio Optimizer

Find the right allocation for SKYE and QURE

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