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SBIO vs. IYZ
Performance
Return for Risk
Drawdowns
Volatility
Dividends

SBIO vs. IYZ

Last updated Jun 9, 2026

SBIO (ALPS Medical Breakthroughs ETF) and IYZ (iShares U.S. Telecommunications ETF) are both exchange-traded funds - SBIO is a Health & Biotech Equities fund tracking the S-Network Medical Breakthroughs Index, while IYZ is a Communications Equities fund tracking the Dow Jones U.S. Select Telecommunications Index. Both are passively managed. Over the past 10 years, SBIO returned 8.36%/yr vs 5.76%/yr for IYZ. At a 0.45 correlation, their price movements are largely independent. SBIO charges 0.50%/yr vs 0.42%/yr for IYZ.

Performance

SBIO vs. IYZ - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in ALPS Medical Breakthroughs ETF (SBIO) and iShares U.S. Telecommunications ETF (IYZ). The values are adjusted to include any dividend payments, if applicable.

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Returns By Period

In the year-to-date period, SBIO achieves a -1.72% return, which is significantly lower than IYZ's 26.58% return. Over the past 10 years, SBIO has outperformed IYZ with an annualized return of 8.36%, while IYZ has yielded a comparatively lower 5.76% annualized return.

SBIO

1D
-0.36%
1M
-9.33%
YTD
-1.72%
6M
-2.48%
1Y
59.38%
3Y*
16.69%
5Y*
1.33%
10Y*
8.36%

IYZ

1D
0.40%
1M
3.16%
YTD
26.58%
6M
29.19%
1Y
51.92%
3Y*
28.42%
5Y*
7.24%
10Y*
5.76%
*Multi-year figures are annualized to reflect compound growth (CAGR)

SBIO vs. IYZ - Yearly Performance Comparison

2026 (YTD)202520242023202220212020201920182017
SBIO
ALPS Medical Breakthroughs ETF		-1.72%55.07%3.81%8.68%-28.08%-17.55%21.17%50.30%-11.81%45.67%
IYZ
iShares U.S. Telecommunications ETF		26.58%29.28%20.53%3.90%-30.29%11.69%4.13%16.14%-8.59%-11.86%

Correlation

The correlation between SBIO and IYZ is 0.31, which is low. Their price movements are largely independent, making them effective diversification partners.

Correlation
Correlation (1Y)
Calculated over the trailing 1-year period

0.31

Correlation (3Y)
Calculated over the trailing 3-year period

0.40

Correlation (5Y)
Calculated over the trailing 5-year period

0.48

Correlation (10Y)
Calculated over the trailing 10-year period

0.46

Correlation (All Time)
Calculated using the full available price history since Jan 2, 2015

0.45

The correlation between SBIO and IYZ shifts across timeframes, from 0.31 (1 year) to 0.48 (5 years), reflecting how their relationship changes across market environments.

Compare stocks, funds, or ETFs

Search for stocks, ETFs, and funds for a quick comparison or use the comparison tool for more options.

ALPS Medical Breakthroughs ETF

iShares U.S. Telecommunications ETF

Often compared with SBIO:
SBIO vs. XBISBIO vs. BBPSBIO vs. GERMSBIO vs. BBCSBIO vs. IBBSBIO vs. IBBQSBIO vs. PBE
Often compared with IYZ:
IYZ vs. XTLIYZ vs. VOXIYZ vs. XLCIYZ vs. IXPIYZ vs. IYRIYZ vs. FBMPXIYZ vs. SPY

Return for Risk

SBIO vs. IYZ — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.
SBIO
SBIO Risk / Return Rank: 7373
Overall Rank
SBIO Sharpe Ratio Rank: 6969
Sharpe Ratio Rank
SBIO Sortino Ratio Rank: 7070
Sortino Ratio Rank
SBIO Omega Ratio Rank: 6060
Omega Ratio Rank
SBIO Calmar Ratio Rank: 8888
Calmar Ratio Rank
SBIO Martin Ratio Rank: 7878
Martin Ratio Rank
IYZ
IYZ Risk / Return Rank: 9191
Overall Rank
IYZ Sharpe Ratio Rank: 9191
Sharpe Ratio Rank
IYZ Sortino Ratio Rank: 8989
Sortino Ratio Rank
IYZ Omega Ratio Rank: 8888
Omega Ratio Rank
IYZ Calmar Ratio Rank: 9595
Calmar Ratio Rank
IYZ Martin Ratio Rank: 9494
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

SBIO vs. IYZ - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for ALPS Medical Breakthroughs ETF (SBIO) and iShares U.S. Telecommunications ETF (IYZ). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

SBIOIYZDifference
Sharpe ratioReturn per unit of total volatility
2.02
2.84

-0.82

Sortino ratioReturn per unit of downside risk
2.85
3.75

-0.90

Omega ratioGain probability vs. loss probability

1.33

1.50

-0.17

Calmar ratioReturn relative to maximum drawdown

4.72

7.11

-2.40

Martin ratioReturn relative to average drawdown

13.54

26.20

-12.66

Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

SBIO vs. IYZ - Sharpe Ratio Comparison

The current SBIO Sharpe Ratio is 2.02, which is comparable to the IYZ Sharpe Ratio of 2.84. The chart below compares the historical Sharpe Ratios of SBIO and IYZ, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

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Sharpe Ratios by Period

SBIOIYZDifference

Sharpe Ratio (1Y)

Calculated over the trailing 1-year period

2.02

2.84

-0.82

Sharpe Ratio (5Y)

Calculated over the trailing 5-year period

0.04

0.39

-0.35

Sharpe Ratio (10Y)

Calculated over the trailing 10-year period

0.25

0.30

-0.05

Sharpe Ratio (All Time)

Calculated using the full available price history

0.21

0.07

+0.14

Drawdowns

SBIO vs. IYZ - Drawdown Comparison

The maximum SBIO drawdown since its inception was -63.06%, smaller than the maximum IYZ drawdown of -77.11%. Use the drawdown chart below to compare losses from any high point for SBIO and IYZ.

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Drawdown Indicators

SBIOIYZDifference

Max Drawdown

Largest peak-to-trough decline

-63.06%

-77.11%

+14.05%

Max Drawdown (1Y)

Largest decline over 1 year

-12.66%

-7.33%

-5.33%

Max Drawdown (3Y)

Largest decline over 3 years

-42.44%

-13.85%

-28.59%

Max Drawdown (5Y)

Largest decline over 5 years

-53.10%

-39.74%

-13.36%

Max Drawdown (10Y)

Largest decline over 10 years

-63.06%

-39.74%

-23.32%

Current Drawdown

Current decline from peak

-17.90%

-6.96%

-10.94%

Average Drawdown

Average peak-to-trough decline

-28.43%

-40.13%

+11.70%

Ulcer Index

Depth and duration of drawdowns from previous peaks

4.40%

1.99%

+2.41%

Volatility

SBIO vs. IYZ - Volatility Comparison

ALPS Medical Breakthroughs ETF (SBIO) has a higher volatility of 9.87% compared to iShares U.S. Telecommunications ETF (IYZ) at 8.23%. This indicates that SBIO's price experiences larger fluctuations and is considered to be riskier than IYZ based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

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Volatility by Period

SBIOIYZDifference

Volatility (1M)

Calculated over the trailing 1-month period

9.87%

8.23%

+1.64%

Volatility (6M)

Calculated over the trailing 6-month period

22.68%

15.34%

+7.34%

Volatility (1Y)

Calculated over the trailing 1-year period

29.62%

18.43%

+11.19%

Volatility (5Y)

Calculated over the trailing 5-year period, annualized

33.56%

18.84%

+14.72%

Volatility (10Y)

Calculated over the trailing 10-year period, annualized

33.18%

19.29%

+13.89%

SBIO vs. IYZ - Expense Ratio Comparison

SBIO has a 0.50% expense ratio, which is higher than IYZ's 0.42% expense ratio.

Dividends

SBIO vs. IYZ - Dividend Comparison

SBIO has not paid dividends to shareholders, while IYZ's dividend yield for the trailing twelve months is around 1.57%.

PositionTTM20252024202320222021202020192018201720162015
IYZ
iShares U.S. Telecommunications ETF		1.57%2.04%1.94%2.27%2.55%2.51%2.60%2.36%2.15%3.54%2.27%1.98%
SBIO
ALPS Medical Breakthroughs ETF		0.00%0.00%3.55%0.22%0.00%0.00%0.00%0.04%2.79%1.77%0.00%0.00%

Frequently Asked Questions

SBIO and IYZ have a correlation of 0.31, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

SBIO has higher volatility (9.87%) compared to IYZ (8.23%). In terms of maximum drawdown, SBIO dropped -63.06% vs IYZ's -77.11%.

On 10-year performance, SBIO leads with 8.36% vs 5.76% for IYZ. On fees, IYZ is cheaper at 0.42% per year. On volatility, IYZ has been the lower-risk option at 8.23%. The better choice depends on whether you care most about return, fees, risk, or income.

Over the 10-year period, SBIO has performed better with a 8.36% return vs 5.76%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.

IYZ is cheaper with a 0.42% expense ratio, compared with 0.50% for SBIO.

IYZ has the higher dividend yield at 1.57%, compared with 0.00% for SBIO.

SBIO is categorized as Health & Biotech Equities, while IYZ is Communications Equities. SBIO tracks S-Network Medical Breakthroughs Index, while IYZ tracks Dow Jones U.S. Select Telecommunications Index. They also come from different issuers: SS&C and iShares. Their fees differ too: 0.50% for SBIO and 0.42% for IYZ.

IYZ currently has the higher Sharpe Ratio (2.84 vs 2.02), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.

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