QURE vs. MBX
QURE (uniQure N.V.) and MBX (MBX Biosciences, Inc) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. Over the past year, QURE returned 56.34% vs 155.06% for MBX. At a 0.25 correlation, their price movements are largely independent.
Performance
QURE vs. MBX - Performance Comparison
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Returns By Period
In the year-to-date period, QURE achieves a 12.83% return, which is significantly higher than MBX's -8.05% return.
QURE
- 1D
- 2.08%
- 1M
- -2.39%
- YTD
- 12.83%
- 6M
- 24.02%
- 1Y
- 56.34%
- 3Y*
- 11.25%
- 5Y*
- -5.87%
- 10Y*
- 8.62%
MBX
- 1D
- -4.23%
- 1M
- -29.21%
- YTD
- -8.05%
- 6M
- -7.61%
- 1Y
- 155.06%
- 3Y*
- —
- 5Y*
- —
- 10Y*
- —
QURE vs. MBX - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | |
|---|---|---|---|
QURE uniQure N.V. | 12.83% | 35.50% | 212.01% |
MBX MBX Biosciences, Inc | -8.05% | 71.13% | -22.07% |
Correlation
The correlation between QURE and MBX is 0.26, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.26 |
Correlation (All Time) Calculated using the full available price history since Sep 16, 2024 | 0.25 |
Fundamentals
QURE:
$1.69B
MBX:
$1.35B
QURE:
-$3.58
MBX:
-$2.30
QURE:
11.34
MBX:
3.09
QURE:
$18.09M
MBX:
$0.00
QURE:
$13.42M
MBX:
-$160.00K
QURE:
-$164.53M
MBX:
-$96.31M
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Return for Risk
QURE vs. MBX — Risk / Return Rank
QURE
MBX
QURE vs. MBX - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for uniQure N.V. (QURE) and MBX Biosciences, Inc (MBX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| QURE | MBX | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -0.96 | ||
| Sortino ratioReturn per unit of downside risk | -0.04 | ||
| Omega ratioGain probability vs. loss probability | 1.43 | 1.33 | +0.10 |
| Calmar ratioReturn relative to maximum drawdown | 0.65 | 4.15 | -3.50 |
| Martin ratioReturn relative to average drawdown | 1.06 | 7.99 | -6.93 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| QURE | MBX | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 0.21 | 1.17 | -0.96 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | -0.04 | — | — |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | 0.07 | — | — |
Sharpe Ratio (All Time)Calculated using the full available price history | 0.05 | 0.11 | -0.06 |
Drawdowns
QURE vs. MBX - Drawdown Comparison
The maximum QURE drawdown since its inception was -95.40%, which is greater than MBX's maximum drawdown of -77.71%. Use the drawdown chart below to compare losses from any high point for QURE and MBX.
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Drawdown Indicators
| QURE | MBX | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -95.40% | -77.71% | -17.69% |
Max Drawdown (1Y)Largest decline over 1 year | -87.21% | -37.60% | -49.61% |
Max Drawdown (3Y)Largest decline over 3 years | -87.21% | — | — |
Max Drawdown (5Y)Largest decline over 5 years | -90.11% | — | — |
Max Drawdown (10Y)Largest decline over 10 years | -95.40% | — | — |
Current DrawdownCurrent decline from peak | -67.15% | -32.78% | -34.37% |
Average DrawdownAverage peak-to-trough decline | -56.58% | -35.04% | -21.54% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 53.50% | 19.50% | +34.00% |
Volatility
QURE vs. MBX - Volatility Comparison
uniQure N.V. (QURE) has a higher volatility of 28.01% compared to MBX Biosciences, Inc (MBX) at 23.40%. This indicates that QURE's price experiences larger fluctuations and is considered to be riskier than MBX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| QURE | MBX | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 28.01% | 23.40% | +4.61% |
Volatility (6M)Calculated over the trailing 6-month period | 92.44% | 57.78% | +34.66% |
Volatility (1Y)Calculated over the trailing 1-year period | 273.61% | 133.96% | +139.65% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 154.08% | 118.74% | +35.34% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 119.92% | 118.74% | +1.18% |
Dividends
QURE vs. MBX - Dividend Comparison
Neither QURE nor MBX has paid dividends to shareholders.
Financials
QURE vs. MBX - Financials Comparison
This section allows you to compare key financial metrics between uniQure N.V. and MBX Biosciences, Inc. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
Frequently Asked Questions
QURE and MBX have a correlation of 0.26, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
QURE has higher volatility (28.01%) compared to MBX (23.40%). In terms of maximum drawdown, QURE dropped -95.40% vs MBX's -77.71%.
MBX currently has the higher Sharpe Ratio (1.17 vs 0.21), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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