QURE vs. DFEN
QURE (uniQure N.V.) is a stock, while DFEN (Direxion Daily Aerospace & Defense Bull 3X Shares) is Leveraged Equities fund tracking the Dow Jones U.S. Select Aerospace & Defense Index (300%). Over the past 5 years, QURE returned -5.23%/yr vs 29.22%/yr for DFEN. At a 0.27 correlation, their price movements are largely independent.
Performance
QURE vs. DFEN - Performance Comparison
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Returns By Period
In the year-to-date period, QURE achieves a 15.21% return, which is significantly higher than DFEN's 13.12% return.
QURE
- 1D
- 2.80%
- 1M
- -5.49%
- YTD
- 15.21%
- 6M
- 41.31%
- 1Y
- 72.42%
- 3Y*
- 10.96%
- 5Y*
- -5.23%
- 10Y*
- 11.46%
DFEN
- 1D
- -2.71%
- 1M
- 7.74%
- YTD
- 13.12%
- 6M
- 20.44%
- 1Y
- 76.99%
- 3Y*
- 64.38%
- 5Y*
- 29.22%
- 10Y*
- —
QURE vs. DFEN - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
QURE uniQure N.V. | 15.21% | 35.50% | 160.86% | -70.14% | 9.31% | -42.60% | -49.58% | 148.65% | 47.12% | 268.23% |
DFEN Direxion Daily Aerospace & Defense Bull 3X Shares | 13.12% | 156.62% | 27.07% | 24.70% | 6.99% | 12.72% | -70.23% | 95.09% | -32.86% | 83.64% |
Correlation
The correlation between QURE and DFEN is 0.10, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.10 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.18 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.26 |
Correlation (All Time) Calculated using the full available price history since May 3, 2017 | 0.27 |
The correlation between QURE and DFEN shifts across timeframes, from 0.10 (1 year) to 0.27 (all time), reflecting how their relationship changes across market environments.
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Return for Risk
QURE vs. DFEN — Risk / Return Rank
QURE
DFEN
QURE vs. DFEN - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for uniQure N.V. (QURE) and Direxion Daily Aerospace & Defense Bull 3X Shares (DFEN). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| QURE | DFEN | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -0.91 | ||
| Sortino ratioReturn per unit of downside risk | +1.13 | ||
| Omega ratioGain probability vs. loss probability | 1.45 | 1.22 | +0.23 |
| Calmar ratioReturn relative to maximum drawdown | 0.83 | 1.85 | -1.02 |
| Martin ratioReturn relative to average drawdown | 1.35 | 4.29 | -2.94 |
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Drawdowns
QURE vs. DFEN - Drawdown Comparison
The maximum QURE drawdown since its inception was -95.40%, roughly equal to the maximum DFEN drawdown of -91.36%. Use the drawdown chart below to compare losses from any high point for QURE and DFEN.
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Drawdown Indicators
| QURE | DFEN | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -95.40% | -91.36% | -4.04% |
Max Drawdown (1Y)Largest decline over 1 year | -87.21% | -41.75% | -45.46% |
Max Drawdown (3Y)Largest decline over 3 years | -87.21% | -43.13% | -44.08% |
Max Drawdown (5Y)Largest decline over 5 years | -90.11% | -55.30% | -34.81% |
Max Drawdown (10Y)Largest decline over 10 years | -95.40% | — | — |
Current DrawdownCurrent decline from peak | -66.46% | -25.87% | -40.59% |
Average DrawdownAverage peak-to-trough decline | -56.61% | -45.20% | -11.41% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 53.75% | 17.99% | +35.76% |
Volatility
QURE vs. DFEN - Volatility Comparison
The current volatility for uniQure N.V. (QURE) is 24.13%, while Direxion Daily Aerospace & Defense Bull 3X Shares (DFEN) has a volatility of 27.31%. This indicates that QURE experiences smaller price fluctuations and is considered to be less risky than DFEN based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| QURE | DFEN | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 24.13% | 27.31% | -3.18% |
Volatility (6M)Calculated over the trailing 6-month period | 92.07% | 55.81% | +36.26% |
Volatility (1Y)Calculated over the trailing 1-year period | 273.03% | 65.81% | +207.22% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 154.02% | 60.74% | +93.28% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 119.76% | 71.66% | +48.10% |
Dividends
QURE vs. DFEN - Dividend Comparison
QURE has not paid dividends to shareholders, while DFEN's dividend yield for the trailing twelve months is around 7.89%.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
DFEN Direxion Daily Aerospace & Defense Bull 3X Shares | 7.89% | 8.89% | 14.12% | 1.13% | 0.46% | 1.89% | 0.48% | 0.50% | 1.07% | 1.50% |
QURE uniQure N.V. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
Frequently Asked Questions
QURE and DFEN have a correlation of 0.10, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
DFEN has higher volatility (27.31%) compared to QURE (24.13%). In terms of maximum drawdown, QURE dropped -95.40% vs DFEN's -91.36%.
DFEN currently has the higher Sharpe Ratio (1.18 vs 0.27), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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