QURE vs. AVGX
QURE (uniQure N.V.) is a stock, while AVGX (Defiance Daily Target 2X Long AVGO ETF) is Leveraged Equities fund actively managed by Defiance. Over the past year, QURE returned 87.10% vs 84.80% for AVGX. At a 0.23 correlation, their price movements are largely independent.
Performance
QURE vs. AVGX - Performance Comparison
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Returns By Period
In the year-to-date period, QURE achieves a 16.97% return, which is significantly lower than AVGX's 26.51% return.
QURE
- 1D
- -6.33%
- 1M
- 32.28%
- YTD
- 16.97%
- 6M
- 23.09%
- 1Y
- 87.10%
- 3Y*
- 12.75%
- 5Y*
- -4.55%
- 10Y*
- 7.16%
AVGX
- 1D
- -25.53%
- 1M
- -8.40%
- YTD
- 26.51%
- 6M
- 0.84%
- 1Y
- 84.80%
- 3Y*
- —
- 5Y*
- —
- 10Y*
- —
QURE vs. AVGX - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | |
|---|---|---|---|
QURE uniQure N.V. | 16.97% | 35.50% | 171.48% |
AVGX Defiance Daily Target 2X Long AVGO ETF | 26.51% | 46.98% | 69.92% |
Correlation
The correlation between QURE and AVGX is 0.16, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.16 |
Correlation (All Time) Calculated using the full available price history since Aug 23, 2024 | 0.23 |
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Return for Risk
QURE vs. AVGX — Risk / Return Rank
QURE
AVGX
QURE vs. AVGX - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for uniQure N.V. (QURE) and Defiance Daily Target 2X Long AVGO ETF (AVGX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| QURE | AVGX | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -0.63 | ||
| Sortino ratioReturn per unit of downside risk | +1.37 | ||
| Omega ratioGain probability vs. loss probability | 1.46 | 1.23 | +0.24 |
| Calmar ratioReturn relative to maximum drawdown | 1.00 | 1.58 | -0.57 |
| Martin ratioReturn relative to average drawdown | 1.64 | 3.51 | -1.87 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| QURE | AVGX | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 0.32 | 0.95 | -0.63 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | -0.03 | — | — |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | 0.06 | — | — |
Sharpe Ratio (All Time)Calculated using the full available price history | 0.05 | 0.86 | -0.81 |
Drawdowns
QURE vs. AVGX - Drawdown Comparison
The maximum QURE drawdown since its inception was -95.40%, which is greater than AVGX's maximum drawdown of -70.97%. Use the drawdown chart below to compare losses from any high point for QURE and AVGX.
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Drawdown Indicators
| QURE | AVGX | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -95.40% | -70.97% | -24.43% |
Max Drawdown (1Y)Largest decline over 1 year | -87.21% | -54.09% | -33.12% |
Max Drawdown (3Y)Largest decline over 3 years | -87.21% | — | — |
Max Drawdown (5Y)Largest decline over 5 years | -90.11% | — | — |
Max Drawdown (10Y)Largest decline over 10 years | -95.40% | — | — |
Current DrawdownCurrent decline from peak | -65.94% | -26.15% | -39.79% |
Average DrawdownAverage peak-to-trough decline | -56.58% | -22.72% | -33.86% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 53.21% | 24.26% | +28.95% |
Volatility
QURE vs. AVGX - Volatility Comparison
The current volatility for uniQure N.V. (QURE) is 28.41%, while Defiance Daily Target 2X Long AVGO ETF (AVGX) has a volatility of 38.30%. This indicates that QURE experiences smaller price fluctuations and is considered to be less risky than AVGX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| QURE | AVGX | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 28.41% | 38.30% | -9.89% |
Volatility (6M)Calculated over the trailing 6-month period | 92.96% | 68.61% | +24.35% |
Volatility (1Y)Calculated over the trailing 1-year period | 273.20% | 89.63% | +183.57% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 154.07% | 106.35% | +47.72% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 119.92% | 106.35% | +13.57% |
Dividends
QURE vs. AVGX - Dividend Comparison
QURE has not paid dividends to shareholders, while AVGX's dividend yield for the trailing twelve months is around 1.31%.
| Position | TTM | 2025 | 2024 |
|---|---|---|---|
AVGX Defiance Daily Target 2X Long AVGO ETF | 1.31% | 1.65% | 0.81% |
QURE uniQure N.V. | 0.00% | 0.00% | 0.00% |
Frequently Asked Questions
QURE and AVGX have a correlation of 0.16, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
AVGX has higher volatility (38.30%) compared to QURE (28.41%). In terms of maximum drawdown, QURE dropped -95.40% vs AVGX's -70.97%.
AVGX currently has the higher Sharpe Ratio (0.95 vs 0.32), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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