PSIL vs. PBE

Last updated Jun 16, 2026

PSIL (AdvisorShares Psychedelics ETF) and PBE (Invesco Dynamic Biotechnology & Genome ETF) are both Health & Biotech Equities funds. PSIL is actively managed, while PBE is passively managed. Over the past 3 years, PSIL returned 6.03%/yr vs 10.91%/yr for PBE. At a 0.43 correlation, their price movements are largely independent. PSIL charges 1.00%/yr vs 0.59%/yr for PBE.

Performance

PSIL vs. PBE - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in AdvisorShares Psychedelics ETF (PSIL) and Invesco Dynamic Biotechnology & Genome ETF (PBE). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, PSIL achieves a 12.35% return, which is significantly higher than PBE's 3.32% return.

PSIL

• 1D: -4.32%
• 1M: -3.41%
• YTD: 12.35%
• 6M: 10.46%
• 1Y: 52.66%
• 3Y*: 6.03%
• 5Y*: —
• 10Y*: —

PBE

• 1D: 0.81%
• 1M: 4.85%
• YTD: 3.32%
• 6M: 5.17%
• 1Y: 34.13%
• 3Y*: 10.91%
• 5Y*: 2.31%
• 10Y*: 8.90%

*Multi-year figures are annualized to reflect compound growth (CAGR)

PSIL vs. PBE - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021
PSIL AdvisorShares Psychedelics ETF	12.35%	74.55%	-19.50%	-25.12%	-67.24%	-42.72%
PBE Invesco Dynamic Biotechnology & Genome ETF	3.32%	24.84%	1.10%	3.71%	-10.83%	-6.77%

Correlation

The correlation between PSIL and PBE is 0.41, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.41
Correlation (3Y) Calculated over the trailing 3-year period	0.41
Correlation (All Time) Calculated using the full available price history since Sep 16, 2021	0.43

PSIL vs. PBE - Sectors Allocation Comparison

Sectors	PSIL	PBE
Healthcare	100.0%	99.9%
Basic Materials	-	-
Communication Services	-	-
Consumer Cyclical	-	-
Consumer Defensive	-	-
Energy	-	-
Financial Services	-	0.2%
Industrials	-	-
Real Estate	-	-
Technology	-	-
Utilities	-	-

Return for Risk

PSIL vs. PBE — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

PSIL

PSIL Risk / Return Rank: 39
PSIL Sharpe Ratio Rank: 35
PSIL Sortino Ratio Rank: 35
PSIL Omega Ratio Rank: 34
PSIL Calmar Ratio Rank: 54
PSIL Martin Ratio Rank: 36

PBE

PBE Risk / Return Rank: 58
PBE Sharpe Ratio Rank: 58
PBE Sortino Ratio Rank: 63
PBE Omega Ratio Rank: 53
PBE Calmar Ratio Rank: 63
PBE Martin Ratio Rank: 52

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

PSIL vs. PBE - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for AdvisorShares Psychedelics ETF (PSIL) and Invesco Dynamic Biotechnology & Genome ETF (PBE). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	PSIL	PBE	Difference
Sharpe ratio: Return per unit of total volatility	1.25	1.81	-0.56
Sortino ratio: Return per unit of downside risk	1.80	2.68	-0.89
Omega ratio: Gain probability vs. loss probability	1.23	1.31	-0.08
Calmar ratio: Return relative to maximum drawdown	2.60	2.92	-0.33
Martin ratio: Return relative to average drawdown	5.38	8.21	-2.82

PSIL vs. PBE - Sharpe Ratio Comparison

The current PSIL Sharpe Ratio is 1.25, which is lower than the PBE Sharpe Ratio of 1.81. The chart below compares the historical Sharpe Ratios of PSIL and PBE, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

PSIL vs. PBE - Drawdown Comparison

The maximum PSIL drawdown since its inception was -92.72%, which is greater than PBE's maximum drawdown of -45.69%. Use the drawdown chart below to compare losses from any high point for PSIL and PBE.

Drawdown Indicators

	PSIL	PBE	Difference
Max Drawdown Largest peak-to-trough decline	-92.72%	-45.69%	-47.03%
Max Drawdown (1Y) Largest decline over 1 year	-20.38%	-11.73%	-8.65%
Max Drawdown (3Y) Largest decline over 3 years	-64.62%	-22.43%	-42.19%
Max Drawdown (5Y) Largest decline over 5 years	—	-34.71%	—
Max Drawdown (10Y) Largest decline over 10 years	—	-37.84%	—
Current Drawdown Current decline from peak	-78.15%	-1.00%	-77.15%
Average Drawdown Average peak-to-trough decline	-76.71%	-16.21%	-60.50%
Ulcer Index Depth and duration of drawdowns from previous peaks	9.81%	4.17%	+5.64%

Volatility

PSIL vs. PBE - Volatility Comparison

AdvisorShares Psychedelics ETF (PSIL) has a higher volatility of 12.21% compared to Invesco Dynamic Biotechnology & Genome ETF (PBE) at 6.04%. This indicates that PSIL's price experiences larger fluctuations and is considered to be riskier than PBE based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	PSIL	PBE	Difference
Volatility (1M) Calculated over the trailing 1-month period	12.21%	6.04%	+6.17%
Volatility (6M) Calculated over the trailing 6-month period	28.74%	13.67%	+15.07%
Volatility (1Y) Calculated over the trailing 1-year period	42.53%	19.01%	+23.52%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	63.03%	22.48%	+40.55%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	63.03%	24.91%	+38.12%

PSIL vs. PBE - Expense Ratio Comparison

PSIL has a 1.00% expense ratio, which is higher than PBE's 0.59% expense ratio.

Dividends

PSIL vs. PBE - Dividend Comparison

PSIL's dividend yield for the trailing twelve months is around 8.90%, more than PBE's 1.02% yield.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
PBE Invesco Dynamic Biotechnology & Genome ETF	1.02%	1.00%	0.05%	0.02%	0.00%	0.00%	0.04%	0.00%	0.00%	0.57%	0.38%	1.12%
PSIL AdvisorShares Psychedelics ETF	8.90%	10.95%	1.49%	0.24%	2.91%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Frequently Asked Questions

Can I hold both PSIL and PBE in my portfolio?

PSIL and PBE have a correlation of 0.41, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, PSIL or PBE?

PSIL has higher volatility (12.21%) compared to PBE (6.04%). In terms of maximum drawdown, PSIL dropped -92.72% vs PBE's -45.69%.

Which ETF is better, PSIL or PBE?

On 3-year performance, PBE leads with 10.91% vs 6.03% for PSIL. On fees, PBE is cheaper at 0.59% per year. On volatility, PBE has been the lower-risk option at 6.04%. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF has performed better, PSIL or PBE?

Over the 3-year period, PBE has performed better with a 10.91% return vs 6.03%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.

Which ETF is cheaper, PSIL or PBE?

PBE is cheaper with a 0.59% expense ratio, compared with 1.00% for PSIL.

Which ETF pays a higher dividend yield, PSIL or PBE?

PSIL has the higher dividend yield at 8.90%, compared with 1.02% for PBE.

What is the main difference between PSIL and PBE?

They also come from different issuers: AdvisorShares and Invesco. Their fees differ too: 1.00% for PSIL and 0.59% for PBE.

Which has better risk-adjusted returns?

PBE currently has the higher Sharpe Ratio (1.81 vs 1.25), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.