PRAX vs. LITE

Last updated Jun 23, 2026

PRAX (Praxis Precision Medicines, Inc.) and LITE (Lumentum Holdings Inc.) are both stocks. PRAX operates in Biotechnology (Healthcare), while LITE operates in Communication Equipment (Technology). Over the past 5 years, PRAX returned 0.91%/yr vs 61.67%/yr for LITE. At a 0.20 correlation, their price movements are largely independent.

Performance

PRAX vs. LITE - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Praxis Precision Medicines, Inc. (PRAX) and Lumentum Holdings Inc. (LITE). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, PRAX achieves a 2.93% return, which is significantly lower than LITE's 142.53% return.

PRAX

• 1D: 7.47%
• 1M: -11.69%
• YTD: 2.93%
• 6M: 8.20%
• 1Y: 616.56%
• 3Y*: 160.82%
• 5Y*: 0.91%
• 10Y*: —

LITE

• 1D: 5.17%
• 1M: -5.59%
• YTD: 142.53%
• 6M: 129.28%
• 1Y: 897.02%
• 3Y*: 152.86%
• 5Y*: 61.67%
• 10Y*: 43.45%

*Multi-year figures are annualized to reflect compound growth (CAGR)

PRAX vs. LITE - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020
PRAX Praxis Precision Medicines, Inc.	2.93%	282.98%	245.42%	-37.59%	-87.92%	-64.19%	112.10%
LITE Lumentum Holdings Inc.	142.53%	339.06%	60.15%	0.48%	-50.68%	11.57%	13.48%

Correlation

The correlation between PRAX and LITE is 0.16, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.16
Correlation (3Y) Calculated over the trailing 3-year period	0.19
Correlation (5Y) Calculated over the trailing 5-year period	0.20
Correlation (All Time) Calculated using the full available price history since Oct 16, 2020	0.20

Fundamentals

Market Cap PRAX : $8.76B LITE : $86.00B
EPS PRAX : -$13.77 LITE : $5.26
PB Ratio PRAX : 6.22 LITE : 28.92
Total Revenue (TTM) PRAX : -$92.00K LITE : $2.49B
Gross Profit (TTM) PRAX : -$128.83M LITE : $938.50M
EBITDA (TTM) PRAX : -$344.68M LITE : $470.10M

Return for Risk

PRAX vs. LITE — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

PRAX

PRAX Risk / Return Rank: 98
PRAX Sharpe Ratio Rank: 96
PRAX Sortino Ratio Rank: 99
PRAX Omega Ratio Rank: 98
PRAX Calmar Ratio Rank: 99
PRAX Martin Ratio Rank: 99

LITE

LITE Risk / Return Rank: 99
LITE Sharpe Ratio Rank: 100
LITE Sortino Ratio Rank: 98
LITE Omega Ratio Rank: 97
LITE Calmar Ratio Rank: 100
LITE Martin Ratio Rank: 100

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

PRAX vs. LITE - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Praxis Precision Medicines, Inc. (PRAX) and Lumentum Holdings Inc. (LITE). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	PRAX	LITE	Difference
Sharpe ratio: Return per unit of total volatility	3.13	10.42	-7.29
Sortino ratio: Return per unit of downside risk	6.70	5.21	+1.49
Omega ratio: Gain probability vs. loss probability	1.86	1.68	+0.18
Calmar ratio: Return relative to maximum drawdown	17.13	31.57	-14.45
Martin ratio: Return relative to average drawdown	48.37	111.29	-62.92

PRAX vs. LITE - Sharpe Ratio Comparison

The current PRAX Sharpe Ratio is 3.13, which is lower than the LITE Sharpe Ratio of 10.42. The chart below compares the historical Sharpe Ratios of PRAX and LITE, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

PRAX vs. LITE - Drawdown Comparison

The maximum PRAX drawdown since its inception was -98.67%, which is greater than LITE's maximum drawdown of -66.89%. Use the drawdown chart below to compare losses from any high point for PRAX and LITE.

Drawdown Indicators

	PRAX	LITE	Difference
Max Drawdown Largest peak-to-trough decline	-98.67%	-66.89%	-31.78%
Max Drawdown (1Y) Largest decline over 1 year	-36.33%	-28.70%	-7.63%
Max Drawdown (3Y) Largest decline over 3 years	-68.64%	-50.63%	-18.01%
Max Drawdown (5Y) Largest decline over 5 years	-96.50%	-66.48%	-30.02%
Max Drawdown (10Y) Largest decline over 10 years	—	-66.89%	—
Current Drawdown Current decline from peak	-66.40%	-15.11%	-51.29%
Average Drawdown Average peak-to-trough decline	-80.53%	-23.56%	-56.97%
Ulcer Index Depth and duration of drawdowns from previous peaks	12.84%	8.13%	+4.71%

Volatility

PRAX vs. LITE - Volatility Comparison

Praxis Precision Medicines, Inc. (PRAX) has a higher volatility of 32.66% compared to Lumentum Holdings Inc. (LITE) at 28.51%. This indicates that PRAX's price experiences larger fluctuations and is considered to be riskier than LITE based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	PRAX	LITE	Difference
Volatility (1M) Calculated over the trailing 1-month period	32.66%	28.51%	+4.15%
Volatility (6M) Calculated over the trailing 6-month period	48.71%	68.81%	-20.10%
Volatility (1Y) Calculated over the trailing 1-year period	199.36%	87.18%	+112.18%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	127.61%	60.18%	+67.43%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	123.86%	56.72%	+67.14%

Dividends

PRAX vs. LITE - Dividend Comparison

Neither PRAX nor LITE has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both PRAX and LITE in my portfolio?

PRAX and LITE have a correlation of 0.16, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, PRAX or LITE?

PRAX has higher volatility (32.66%) compared to LITE (28.51%). In terms of maximum drawdown, PRAX dropped -98.67% vs LITE's -66.89%.

Which has better risk-adjusted returns?

LITE currently has the higher Sharpe Ratio (10.42 vs 3.13), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.