PRAX vs. SMH

Last updated Jun 4, 2026

PRAX (Praxis Precision Medicines, Inc.) is a stock, while SMH (VanEck Semiconductor ETF) is Semiconductors fund tracking the MVIS US Listed Semiconductor 25 Index. Over the past 5 years, PRAX returned -0.71%/yr vs 39.21%/yr for SMH. At a 0.22 correlation, their price movements are largely independent.

Performance

PRAX vs. SMH - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Praxis Precision Medicines, Inc. (PRAX) and VanEck Semiconductor ETF (SMH). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, PRAX achieves a -5.36% return, which is significantly lower than SMH's 77.13% return.

PRAX

• 1D: 8.08%
• 1M: -17.38%
• YTD: -5.36%
• 6M: 49.84%
• 1Y: 577.01%
• 3Y*: 164.05%
• 5Y*: -0.71%
• 10Y*: —

SMH

• 1D: 0.90%
• 1M: 25.87%
• YTD: 77.13%
• 6M: 75.61%
• 1Y: 157.20%
• 3Y*: 64.17%
• 5Y*: 39.21%
• 10Y*: 37.68%

*Multi-year figures are annualized to reflect compound growth (CAGR)

PRAX vs. SMH - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020
PRAX Praxis Precision Medicines, Inc.	-5.36%	282.98%	245.42%	-37.59%	-87.92%	-64.19%	97.91%
SMH VanEck Semiconductor ETF	77.13%	49.17%	39.10%	73.38%	-33.53%	42.13%	17.95%

Correlation

The correlation between PRAX and SMH is 0.16, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.16
Correlation (3Y) Calculated over the trailing 3-year period	0.17
Correlation (5Y) Calculated over the trailing 5-year period	0.22
Correlation (All Time) Calculated using the full available price history since Oct 19, 2020	0.22

Return for Risk

PRAX vs. SMH — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

PRAX

PRAX Risk / Return Rank: 98
PRAX Sharpe Ratio Rank: 94
PRAX Sortino Ratio Rank: 99
PRAX Omega Ratio Rank: 98
PRAX Calmar Ratio Rank: 99
PRAX Martin Ratio Rank: 99

SMH

SMH Risk / Return Rank: 96
SMH Sharpe Ratio Rank: 98
SMH Sortino Ratio Rank: 95
SMH Omega Ratio Rank: 95
SMH Calmar Ratio Rank: 97
SMH Martin Ratio Rank: 96

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

PRAX vs. SMH - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Praxis Precision Medicines, Inc. (PRAX) and VanEck Semiconductor ETF (SMH). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	PRAX	SMH	Difference
Sharpe ratio Return per unit of total volatility	2.93	5.19	-2.25
Sortino ratio Return per unit of downside risk	6.64	5.22	+1.42
Omega ratio Gain probability vs. loss probability	1.86	1.72	+0.14
Calmar ratio Return relative to maximum drawdown	16.02	10.59	+5.43
Martin ratio Return relative to average drawdown	50.51	40.63	+9.88
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

PRAX vs. SMH - Sharpe Ratio Comparison

The current PRAX Sharpe Ratio is 2.93, which is lower than the SMH Sharpe Ratio of 5.19. The chart below compares the historical Sharpe Ratios of PRAX and SMH, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	PRAX	SMH	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	2.93	5.19	-2.25
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.01	1.13	-1.13
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	1.16	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.06	0.34	-0.40

Drawdowns

PRAX vs. SMH - Drawdown Comparison

The maximum PRAX drawdown since its inception was -98.67%, which is greater than SMH's maximum drawdown of -84.96%. Use the drawdown chart below to compare losses from any high point for PRAX and SMH.

Drawdown Indicators

	PRAX	SMH	Difference
Max Drawdown Largest peak-to-trough decline	-98.67%	-84.96%	-13.71%
Max Drawdown (1Y) Largest decline over 1 year	-36.33%	-14.93%	-21.40%
Max Drawdown (3Y) Largest decline over 3 years	-68.64%	-35.74%	-32.90%
Max Drawdown (5Y) Largest decline over 5 years	-96.50%	-45.30%	-51.20%
Max Drawdown (10Y) Largest decline over 10 years	—	-45.30%	—
Current Drawdown Current decline from peak	-69.11%	0.00%	-69.11%
Average Drawdown Average peak-to-trough decline	-80.66%	-41.09%	-39.57%
Ulcer Index Depth and duration of drawdowns from previous peaks	11.50%	3.89%	+7.61%

Volatility

PRAX vs. SMH - Volatility Comparison

Praxis Precision Medicines, Inc. (PRAX) has a higher volatility of 30.10% compared to VanEck Semiconductor ETF (SMH) at 11.47%. This indicates that PRAX's price experiences larger fluctuations and is considered to be riskier than SMH based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	PRAX	SMH	Difference
Volatility (1M) Calculated over the trailing 1-month period	30.10%	11.47%	+18.63%
Volatility (6M) Calculated over the trailing 6-month period	54.82%	24.29%	+30.53%
Volatility (1Y) Calculated over the trailing 1-year period	198.58%	30.56%	+168.02%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	127.54%	35.01%	+92.53%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	124.23%	32.57%	+91.66%

Dividends

PRAX vs. SMH - Dividend Comparison

PRAX has not paid dividends to shareholders, while SMH's dividend yield for the trailing twelve months is around 0.17%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
PRAX Praxis Precision Medicines, Inc.	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
SMH VanEck Semiconductor ETF	0.17%	0.31%	0.44%	0.60%	1.18%	0.51%	0.69%	1.50%	1.88%	1.43%	0.80%	2.14%

Frequently Asked Questions

Can I hold both PRAX and SMH in my portfolio?

PRAX and SMH have a correlation of 0.16, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, PRAX or SMH?

PRAX has higher volatility (30.10%) compared to SMH (11.47%). In terms of maximum drawdown, PRAX dropped -98.67% vs SMH's -84.96%.

Which has better risk-adjusted returns?

SMH currently has the higher Sharpe Ratio (5.19 vs 2.93), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.