Praxis Precision Medicines, Inc. (PRAX)

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The chart shows the growth of an initial investment of $10,000 in Praxis Precision Medicines, Inc., comparing it to the performance of the S&P 500 index or another benchmark. All prices have been adjusted for splits and dividends.

Praxis Precision Medicines, Inc. (PRAX) has returned 9.31% so far this year and 750.78% over the past 12 months.

Based on dividend-adjusted daily data since Oct 16, 2020, PRAX's average daily return is +0.27%, while the average monthly return is +6.75%. At this rate, your investment would double in approximately 0.9 years.

Historically, 48% of months were positive and 52% were negative. The best month was Oct 2025 with a return of +275.0%, while the worst month was Mar 2023 at -73.6%. The longest winning streak lasted 5 consecutive months, and the longest losing streak was 7 months.

On a daily basis, PRAX closed higher 50% of trading days. The best single day was Oct 16, 2025 with a return of +183.7%, while the worst single day was Jun 6, 2022 at -78.1%.

Praxis Precision Medicines, Inc. has an annualized alpha of 73.47%, beta of 1.08, and R² of 0.02 versus S&P 500 Index. Calculated based on daily prices since October 19, 2020.

• This stock captured 212.92% of S&P 500 Index gains and 208.30% of its losses — amplifying both gains and losses, but participating more in upside than downside.
• R² of 0.02 means this stock moves largely independently of S&P 500 Index — capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.

PRAX ranks 99 for risk / return — in the top 99% of stocks on our site. This means strong returns relative to risk — exactly what professional investors look for. Well-suited for investors who want to maximize return per unit of risk.

The table below present risk-adjusted performance metrics for Praxis Precision Medicines, Inc. (PRAX) and compare them to a chosen benchmark (S&P 500 Index).

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.

The table below displays the maximum drawdowns of the Praxis Precision Medicines, Inc.. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the Praxis Precision Medicines, Inc. was 98.67%, occurring on Mar 30, 2023. The portfolio has not yet recovered.

The current Praxis Precision Medicines, Inc. drawdown is 64.32%.

The chart below shows the rolling one-month volatility.

The chart below illustrates the trends in the financial health of Praxis Precision Medicines, Inc. over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.

The Valuation section provides an overview of how Praxis Precision Medicines, Inc. is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.