PLSE vs. NVDA

Last updated Jun 4, 2026

PLSE (Pulse Biosciences, Inc.) and NVDA (NVIDIA Corporation) are both stocks. PLSE operates in Medical Instruments & Supplies (Healthcare), while NVDA operates in Semiconductors (Technology). Over the past 10 years, PLSE returned 19.02%/yr vs 68.84%/yr for NVDA. At a 0.17 correlation, their price movements are largely independent.

Performance

PLSE vs. NVDA - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Pulse Biosciences, Inc. (PLSE) and NVIDIA Corporation (NVDA). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, PLSE achieves a 82.01% return, which is significantly higher than NVDA's 15.15% return. Over the past 10 years, PLSE has underperformed NVDA with an annualized return of 19.02%, while NVDA has yielded a comparatively higher 68.84% annualized return.

PLSE

• 1D: 2.92%
• 1M: 24.76%
• YTD: 82.01%
• 6M: 85.25%
• 1Y: 41.75%
• 3Y*: 57.47%
• 5Y*: 6.15%
• 10Y*: 19.02%

NVDA

• 1D: -3.62%
• 1M: 8.20%
• YTD: 15.15%
• 6M: 19.59%
• 1Y: 52.10%
• 3Y*: 76.15%
• 5Y*: 65.05%
• 10Y*: 68.84%

*Multi-year figures are annualized to reflect compound growth (CAGR)

PLSE vs. NVDA - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
PLSE Pulse Biosciences, Inc.	82.01%	-21.14%	42.24%	341.88%	-81.30%	-37.93%	77.93%	17.02%	-51.44%	263.08%
NVDA NVIDIA Corporation	15.15%	38.92%	171.25%	239.02%	-50.26%	125.48%	122.30%	76.94%	-30.82%	81.99%

Correlation

The correlation between PLSE and NVDA is 0.17, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.17
Correlation (3Y) Calculated over the trailing 3-year period	0.15
Correlation (5Y) Calculated over the trailing 5-year period	0.18
Correlation (10Y) Calculated over the trailing 10-year period	0.17
Correlation (All Time) Calculated using the full available price history since May 19, 2016	0.17

Fundamentals

Market Cap PLSE : $1.69B NVDA : $5.24T
EPS PLSE : -$1.11 NVDA : $6.53
PS Ratio PLSE : 2.24K NVDA : 20.72
PB Ratio PLSE : 25.55 NVDA : 26.80
Total Revenue (TTM) PLSE : $751.00K NVDA : $253.49B
Gross Profit (TTM) PLSE : -$684.00K NVDA : $187.95B
EBITDA (TTM) PLSE : -$73.79M NVDA : $192.76B

Return for Risk

PLSE vs. NVDA — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

PLSE

PLSE Risk / Return Rank: 63
PLSE Sharpe Ratio Rank: 58
PLSE Sortino Ratio Rank: 66
PLSE Omega Ratio Rank: 63
PLSE Calmar Ratio Rank: 64
PLSE Martin Ratio Rank: 62

NVDA

NVDA Risk / Return Rank: 78
NVDA Sharpe Ratio Rank: 81
NVDA Sortino Ratio Rank: 77
NVDA Omega Ratio Rank: 73
NVDA Calmar Ratio Rank: 79
NVDA Martin Ratio Rank: 79

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

PLSE vs. NVDA - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Pulse Biosciences, Inc. (PLSE) and NVIDIA Corporation (NVDA). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	PLSE	NVDA	Difference
Sharpe ratio Return per unit of total volatility	0.49	1.53	-1.04
Sortino ratio Return per unit of downside risk	1.57	2.15	-0.58
Omega ratio Gain probability vs. loss probability	1.19	1.26	-0.07
Calmar ratio Return relative to maximum drawdown	1.15	2.59	-1.44
Martin ratio Return relative to average drawdown	2.21	6.36	-4.15
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

PLSE vs. NVDA - Sharpe Ratio Comparison

The current PLSE Sharpe Ratio is 0.49, which is lower than the NVDA Sharpe Ratio of 1.53. The chart below compares the historical Sharpe Ratios of PLSE and NVDA, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	PLSE	NVDA	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	0.49	1.53	-1.04
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.06	1.27	-1.20
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.21	1.39	-1.18
Sharpe Ratio (All Time) Calculated using the full available price history	0.21	0.63	-0.41

Drawdowns

PLSE vs. NVDA - Drawdown Comparison

The maximum PLSE drawdown since its inception was -97.22%, which is greater than NVDA's maximum drawdown of -89.72%. Use the drawdown chart below to compare losses from any high point for PLSE and NVDA.

Drawdown Indicators

	PLSE	NVDA	Difference
Max Drawdown Largest peak-to-trough decline	-97.22%	-89.72%	-7.50%
Max Drawdown (1Y) Largest decline over 1 year	-36.51%	-20.21%	-16.30%
Max Drawdown (3Y) Largest decline over 3 years	-55.90%	-36.88%	-19.02%
Max Drawdown (5Y) Largest decline over 5 years	-95.38%	-66.34%	-29.04%
Max Drawdown (10Y) Largest decline over 10 years	-97.22%	-66.34%	-30.88%
Current Drawdown Current decline from peak	-43.55%	-8.90%	-34.65%
Average Drawdown Average peak-to-trough decline	-59.75%	-36.21%	-23.54%
Ulcer Index Depth and duration of drawdowns from previous peaks	19.04%	8.21%	+10.83%

Volatility

PLSE vs. NVDA - Volatility Comparison

Pulse Biosciences, Inc. (PLSE) has a higher volatility of 28.86% compared to NVIDIA Corporation (NVDA) at 12.53%. This indicates that PLSE's price experiences larger fluctuations and is considered to be riskier than NVDA based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	PLSE	NVDA	Difference
Volatility (1M) Calculated over the trailing 1-month period	28.86%	12.53%	+16.33%
Volatility (6M) Calculated over the trailing 6-month period	69.05%	25.54%	+43.51%
Volatility (1Y) Calculated over the trailing 1-year period	84.91%	34.22%	+50.69%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	97.99%	51.69%	+46.30%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	91.70%	49.80%	+41.90%

Dividends

PLSE vs. NVDA - Dividend Comparison

PLSE has not paid dividends to shareholders, while NVDA's dividend yield for the trailing twelve months is around 0.02%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
NVDA NVIDIA Corporation	0.02%	0.02%	0.03%	0.03%	0.11%	0.05%	0.12%	0.27%	0.46%	0.29%	0.45%	1.20%
PLSE Pulse Biosciences, Inc.	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Financials

Frequently Asked Questions

Can I hold both PLSE and NVDA in my portfolio?

PLSE and NVDA have a correlation of 0.17, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, PLSE or NVDA?

PLSE has higher volatility (28.86%) compared to NVDA (12.53%). In terms of maximum drawdown, PLSE dropped -97.22% vs NVDA's -89.72%.

Which has better risk-adjusted returns?

NVDA currently has the higher Sharpe Ratio (1.53 vs 0.49), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.