PG vs. DFTX

Last updated Jun 13, 2026

PG (The Procter & Gamble Company) and DFTX (Definium Therapeutics, Inc) are both stocks. PG operates in Household & Personal Products (Consumer Defensive), while DFTX operates in Biotechnology (Healthcare). Over the past 3 years, PG returned 3.69%/yr vs 87.91%/yr for DFTX. At a 0.02 correlation, their price movements are largely independent.

Performance

PG vs. DFTX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in The Procter & Gamble Company (PG) and Definium Therapeutics, Inc (DFTX). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, PG achieves a 5.93% return, which is significantly lower than DFTX's 84.84% return.

PG

• 1D: 0.86%
• 1M: 4.83%
• YTD: 5.93%
• 6M: 6.28%
• 1Y: -3.97%
• 3Y*: 3.69%
• 5Y*: 4.73%
• 10Y*: 8.96%

DFTX

• 1D: 2.65%
• 1M: 15.93%
• YTD: 84.84%
• 6M: 97.21%
• 1Y: 245.19%
• 3Y*: 87.91%
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

PG vs. DFTX - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022
PG The Procter & Gamble Company	5.93%	-12.26%	17.25%	-0.86%	5.94%
DFTX Definium Therapeutics, Inc	84.84%	92.39%	90.16%	66.36%	-78.74%

Correlation

The correlation between PG and DFTX is 0.01, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.01
Correlation (3Y) Calculated over the trailing 3-year period	0.02
Correlation (All Time) Calculated using the full available price history since Jul 11, 2022	0.02

Fundamentals

Market Cap PG : $361.53B DFTX : $2.69B
EPS PG : $5.23 DFTX : -$2.57
PB Ratio PG : 6.70 DFTX : 9.66
Total Revenue (TTM) PG : $86.72B DFTX : $0.00
Gross Profit (TTM) PG : $43.64B DFTX : $0.00
EBITDA (TTM) PG : $22.63B DFTX : -$206.36M

Return for Risk

PG vs. DFTX — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

PG

PG Risk / Return Rank: 28
PG Sharpe Ratio Rank: 30
PG Sortino Ratio Rank: 25
PG Omega Ratio Rank: 26
PG Calmar Ratio Rank: 31
PG Martin Ratio Rank: 31

DFTX

DFTX Risk / Return Rank: 96
DFTX Sharpe Ratio Rank: 98
DFTX Sortino Ratio Rank: 95
DFTX Omega Ratio Rank: 92
DFTX Calmar Ratio Rank: 97
DFTX Martin Ratio Rank: 98

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

PG vs. DFTX - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for The Procter & Gamble Company (PG) and Definium Therapeutics, Inc (DFTX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	PG	DFTX	Difference
Sharpe ratio: Return per unit of total volatility	-0.30	3.89	-4.20
Sortino ratio: Return per unit of downside risk	-0.31	3.93	-4.24
Omega ratio: Gain probability vs. loss probability	0.97	1.46	-0.49
Calmar ratio: Return relative to maximum drawdown	-0.37	9.71	-10.08
Martin ratio: Return relative to average drawdown	-0.68	30.51	-31.19

PG vs. DFTX - Sharpe Ratio Comparison

The current PG Sharpe Ratio is -0.30, which is lower than the DFTX Sharpe Ratio of 3.89. The chart below compares the historical Sharpe Ratios of PG and DFTX, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

PG vs. DFTX - Drawdown Comparison

The maximum PG drawdown since its inception was -54.25%, smaller than the maximum DFTX drawdown of -86.01%. Use the drawdown chart below to compare losses from any high point for PG and DFTX.

Drawdown Indicators

	PG	DFTX	Difference
Max Drawdown Largest peak-to-trough decline	-54.25%	-86.01%	+31.76%
Max Drawdown (1Y) Largest decline over 1 year	-15.52%	-24.79%	+9.27%
Max Drawdown (3Y) Largest decline over 3 years	-21.15%	-58.38%	+37.23%
Max Drawdown (5Y) Largest decline over 5 years	-23.77%	—	—
Max Drawdown (10Y) Largest decline over 10 years	-23.77%	—	—
Current Drawdown Current decline from peak	-13.29%	0.00%	-13.29%
Average Drawdown Average peak-to-trough decline	-12.16%	-51.22%	+39.06%
Ulcer Index Depth and duration of drawdowns from previous peaks	8.80%	7.93%	+0.87%

Volatility

PG vs. DFTX - Volatility Comparison

The current volatility for The Procter & Gamble Company (PG) is 6.99%, while Definium Therapeutics, Inc (DFTX) has a volatility of 15.21%. This indicates that PG experiences smaller price fluctuations and is considered to be less risky than DFTX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	PG	DFTX	Difference
Volatility (1M) Calculated over the trailing 1-month period	6.99%	15.21%	-8.22%
Volatility (6M) Calculated over the trailing 6-month period	15.01%	38.79%	-23.78%
Volatility (1Y) Calculated over the trailing 1-year period	18.78%	61.83%	-43.05%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	17.82%	83.94%	-66.12%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	19.05%	83.94%	-64.89%

Dividends

PG vs. DFTX - Dividend Comparison

PG's dividend yield for the trailing twelve months is around 2.85%, while DFTX has not paid dividends to shareholders.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
DFTX Definium Therapeutics, Inc	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
PG The Procter & Gamble Company	2.85%	2.91%	2.36%	2.55%	2.38%	2.08%	2.24%	2.37%	3.09%	2.98%	3.18%	3.31%

Financials

Frequently Asked Questions

Can I hold both PG and DFTX in my portfolio?

PG and DFTX have a correlation of 0.01, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, PG or DFTX?

DFTX has higher volatility (15.21%) compared to PG (6.99%). In terms of maximum drawdown, PG dropped -54.25% vs DFTX's -86.01%.

Which has better risk-adjusted returns?

DFTX currently has the higher Sharpe Ratio (3.89 vs -0.30), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.