DFTX vs. ATAI

Last updated Aug 1, 2026

DFTX (Definium Therapeutics, Inc) and ATAI (Atai Life Sciences N.V.) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. Over the past 3 years, DFTX returned 107.23%/yr vs 51.86%/yr for ATAI. Their 0.44 correlation means their historical movements had little consistent relationship.

Performance

DFTX vs. ATAI - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Definium Therapeutics, Inc (DFTX) and Atai Life Sciences N.V. (ATAI). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, DFTX achieves a 225.02% return, which is significantly higher than ATAI's 75.55% return.

DFTX

• 1D: -2.18%
• 1M: -1.52%
• 6M: 157.82%
• YTD: 225.02%
• 1Y: 415.64%
• 3Y*: 107.23%
• 5Y*: —
• 10Y*: —
• ALL TIME*: 42.51%

ATAI

• 1D: 0.00%
• 1M: 38.34%
• 6M: 90.96%
• YTD: 75.55%
• 1Y: 72.18%
• 3Y*: 51.86%
• 5Y*: -14.26%
• 10Y*: —
• ALL TIME*: -18.92%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison

Position	Avg. Volume Value (2W)	Avg. Volume Value (1M)	Avg. Volume Value (3M)
ATAI Atai Life Sciences N.V.	$95.05M	$137.83M	$67.37M
DFTX Definium Therapeutics, Inc	$64.44M	$84.24M	$99.34M

DFTX vs. ATAI - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022
DFTX Definium Therapeutics, Inc	225.02%	92.39%	90.16%	66.36%	-78.74%
ATAI Atai Life Sciences N.V.	75.55%	207.52%	-5.67%	-46.99%	-38.28%

Correlation

The correlation between DFTX and ATAI is 0.52, which is moderate. They have sometimes moved together and sometimes differently, sharing some price drivers without tracking each other closely.

	Correlation
Correlation (1Y) Focuses on recent behavior, but can change the most.	0.52
Correlation (3Y) Balances recent behavior with more history.	0.49
Correlation (All Time) Calculated using the full available price history since Jul 11, 2022	0.44

The correlation between DFTX and ATAI has been stable across timeframes, ranging from 0.44 to 0.52 - a consistent structural relationship.

Fundamentals

Market Cap DFTX : $4.75B ATAI : $2.66B
EPS DFTX : -$2.51 ATAI : -$2.50
PB Ratio DFTX : 16.98 ATAI : 12.92
Total Revenue (TTM) DFTX : $0.00 ATAI : $3.49M
Gross Profit (TTM) DFTX : $0.00 ATAI : $3.49M
EBITDA (TTM) DFTX : -$206.36M ATAI : -$663.38M

Return for Risk

DFTX vs. ATAI — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

DFTX

DFTX Risk / Return Rank: 99
DFTX Sharpe Ratio Rank: 99
DFTX Sortino Ratio Rank: 99
DFTX Omega Ratio Rank: 97
DFTX Calmar Ratio Rank: 99
DFTX Martin Ratio Rank: 99

ATAI

ATAI Risk / Return Rank: 74
ATAI Sharpe Ratio Rank: 74
ATAI Sortino Ratio Rank: 79
ATAI Omega Ratio Rank: 76
ATAI Calmar Ratio Rank: 74
ATAI Martin Ratio Rank: 68

The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

DFTX vs. ATAI - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Definium Therapeutics, Inc (DFTX) and Atai Life Sciences N.V. (ATAI). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	DFTX	ATAI	Difference
Sharpe ratio: Return per unit of total volatility	4.79	0.94	+3.86
Sortino ratio: Return per unit of downside risk	5.11	1.95	+3.16
Omega ratio: Gain probability vs. loss probability	1.60	1.23	+0.37
Calmar ratio: Return relative to maximum drawdown	15.40	1.57	+13.83
Martin ratio: Return relative to average drawdown	47.19	2.43	+44.76

DFTX vs. ATAI - Sharpe Ratio Comparison

The current DFTX Sharpe Ratio is 4.79, which is higher than the ATAI Sharpe Ratio of 0.94. The chart below compares the historical Sharpe Ratios of DFTX and ATAI, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

DFTX vs. ATAI - Drawdown Comparison

The maximum DFTX drawdown since its inception was -86.01%, smaller than the maximum ATAI drawdown of -95.05%. Use the drawdown chart below to compare losses from any high point for DFTX and ATAI.

Drawdown Indicators

	DFTX	ATAI	Difference
Max Drawdown Largest peak-to-trough decline	-86.01%	-95.05%	+9.04%
Max Drawdown (1Y) Largest decline over 1 year	-24.79%	-48.06%	+23.27%
Max Drawdown (3Y) Largest decline over 3 years	-58.38%	-59.23%	+0.85%
Max Drawdown (5Y) Largest decline over 5 years	—	-94.17%	—
Current Drawdown Current decline from peak	-10.18%	-65.81%	+55.63%
Average Drawdown Average peak-to-trough decline	-49.74%	-80.58%	+30.84%
Ulcer Index Depth and duration of drawdowns from previous peaks	8.09%	30.99%	-22.90%

Volatility

DFTX vs. ATAI - Volatility Comparison

The current volatility for Definium Therapeutics, Inc (DFTX) is 16.10%, while Atai Life Sciences N.V. (ATAI) has a volatility of 33.68%. This indicates that DFTX experiences smaller price fluctuations and is considered to be less risky than ATAI based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	DFTX	ATAI	Difference
Volatility (1M) Calculated over the trailing 1-month period	16.10%	33.68%	-17.58%
Volatility (6M) Calculated over the trailing 6-month period	56.99%	61.09%	-4.10%
Volatility (1Y) Calculated over the trailing 1-year period	79.66%	82.57%	-2.91%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	87.09%	85.28%	+1.81%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	87.09%	84.88%	+2.21%

Dividends

DFTX vs. ATAI - Dividend Comparison

Neither DFTX nor ATAI has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both DFTX and ATAI in my portfolio?

DFTX and ATAI have a correlation of 0.52, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, DFTX or ATAI?

ATAI has higher volatility (33.68%) compared to DFTX (16.10%). In terms of maximum drawdown, DFTX dropped -86.01% vs ATAI's -95.05%.

Which has better risk-adjusted returns?

DFTX currently has the higher Sharpe Ratio (4.79 vs 0.94), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.