MDGL vs. TSM
MDGL (Madrigal Pharmaceuticals, Inc.) and TSM (Taiwan Semiconductor Manufacturing Company Limited) are both stocks. MDGL operates in Biotechnology (Healthcare), while TSM operates in Semiconductors (Technology). Over the past 10 years, MDGL returned 46.09%/yr vs 35.80%/yr for TSM. At a 0.22 correlation, their price movements are largely independent.
Performance
MDGL vs. TSM - Performance Comparison
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Returns By Period
In the year-to-date period, MDGL achieves a -17.44% return, which is significantly lower than TSM's 40.22% return. Over the past 10 years, MDGL has outperformed TSM with an annualized return of 46.09%, while TSM has yielded a comparatively lower 35.80% annualized return.
MDGL
- 1D
- 1.37%
- 1M
- -10.95%
- YTD
- -17.44%
- 6M
- -15.87%
- 1Y
- 62.66%
- 3Y*
- 21.44%
- 5Y*
- 34.82%
- 10Y*
- 46.09%
TSM
- 1D
- 0.68%
- 1M
- 5.09%
- YTD
- 40.22%
- 6M
- 45.91%
- 1Y
- 103.01%
- 3Y*
- 60.80%
- 5Y*
- 31.30%
- 10Y*
- 35.80%
MDGL vs. TSM - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
MDGL Madrigal Pharmaceuticals, Inc. | -17.44% | 88.72% | 33.36% | -20.28% | 242.52% | -23.77% | 22.02% | -19.17% | 22.80% | 516.04% |
TSM Taiwan Semiconductor Manufacturing Company Limited | 40.22% | 55.91% | 92.58% | 42.33% | -36.75% | 12.09% | 92.67% | 64.85% | -3.50% | 41.46% |
Correlation
The correlation between MDGL and TSM is 0.09, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.09 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.14 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.20 |
Correlation (10Y) Calculated over the trailing 10-year period | 0.21 |
Correlation (All Time) Calculated using the full available price history since Feb 6, 2007 | 0.22 |
The correlation between MDGL and TSM shifts across timeframes, from 0.09 (1 year) to 0.22 (all time), reflecting how their relationship changes across market environments.
Fundamentals
MDGL:
$13.96B
TSM:
$2.20T
MDGL:
-$12.87
TSM:
NT$373.98
MDGL:
10.21
TSM:
16.87
MDGL:
25.68
TSM:
11.82
MDGL:
$1.13B
TSM:
NT$4.13T
MDGL:
$1.05B
TSM:
NT$2.55T
MDGL:
-$287.63M
TSM:
NT$3.14T
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Return for Risk
MDGL vs. TSM — Risk / Return Rank
MDGL
TSM
MDGL vs. TSM - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Madrigal Pharmaceuticals, Inc. (MDGL) and Taiwan Semiconductor Manufacturing Company Limited (TSM). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| MDGL | TSM | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -1.36 | ||
| Sortino ratioReturn per unit of downside risk | -1.11 | ||
| Omega ratioGain probability vs. loss probability | 1.26 | 1.40 | -0.14 |
| Calmar ratioReturn relative to maximum drawdown | 2.11 | 5.48 | -3.37 |
| Martin ratioReturn relative to average drawdown | 4.63 | 19.42 | -14.79 |
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Drawdowns
MDGL vs. TSM - Drawdown Comparison
The maximum MDGL drawdown since its inception was -98.40%, which is greater than TSM's maximum drawdown of -89.08%. Use the drawdown chart below to compare losses from any high point for MDGL and TSM.
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Drawdown Indicators
| MDGL | TSM | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -98.40% | -89.08% | -9.32% |
Max Drawdown (1Y)Largest decline over 1 year | -29.36% | -18.14% | -11.22% |
Max Drawdown (3Y)Largest decline over 3 years | -52.88% | -36.82% | -16.06% |
Max Drawdown (5Y)Largest decline over 5 years | -61.41% | -56.47% | -4.94% |
Max Drawdown (10Y)Largest decline over 10 years | -82.19% | -56.47% | -25.72% |
Current DrawdownCurrent decline from peak | -20.25% | -4.87% | -15.38% |
Average DrawdownAverage peak-to-trough decline | -58.52% | -42.85% | -15.67% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 13.38% | 5.11% | +8.27% |
Volatility
MDGL vs. TSM - Volatility Comparison
Madrigal Pharmaceuticals, Inc. (MDGL) and Taiwan Semiconductor Manufacturing Company Limited (TSM) have volatilities of 13.71% and 13.42%, respectively, indicating that both stocks experience similar levels of price fluctuations. This suggests that the risk associated with both stocks, as measured by volatility, is nearly the same. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| MDGL | TSM | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 13.71% | 13.42% | +0.29% |
Volatility (6M)Calculated over the trailing 6-month period | 31.76% | 28.65% | +3.11% |
Volatility (1Y)Calculated over the trailing 1-year period | 45.97% | 36.69% | +9.28% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 133.37% | 37.46% | +95.91% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 117.49% | 34.23% | +83.26% |
Dividends
MDGL vs. TSM - Dividend Comparison
MDGL has not paid dividends to shareholders, while TSM's dividend yield for the trailing twelve months is around 0.83%.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
MDGL Madrigal Pharmaceuticals, Inc. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
TSM Taiwan Semiconductor Manufacturing Company Limited | 0.83% | 1.00% | 1.18% | 1.78% | 2.49% | 1.57% | 1.56% | 3.46% | 3.64% | 2.32% | 2.61% | 2.54% |
Financials
MDGL vs. TSM - Financials Comparison
This section allows you to compare key financial metrics between Madrigal Pharmaceuticals, Inc. and Taiwan Semiconductor Manufacturing Company Limited. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
MDGL vs. TSM - Profitability Comparison
MDGL - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Madrigal Pharmaceuticals, Inc. reported a gross profit of 284.49M and revenue of 311.34M. Therefore, the gross margin over that period was 91.4%.
TSM - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Taiwan Semiconductor Manufacturing Company Limited reported a gross profit of 759.06B and revenue of 1.15T. Therefore, the gross margin over that period was 66.3%.
MDGL - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Madrigal Pharmaceuticals, Inc. reported an operating income of -92.72M and revenue of 311.34M, resulting in an operating margin of -29.8%.
TSM - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Taiwan Semiconductor Manufacturing Company Limited reported an operating income of 664.08B and revenue of 1.15T, resulting in an operating margin of 58.0%.
MDGL - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Madrigal Pharmaceuticals, Inc. reported a net income of -94.39M and revenue of 311.34M, resulting in a net margin of -30.3%.
TSM - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Taiwan Semiconductor Manufacturing Company Limited reported a net income of 578.40B and revenue of 1.15T, resulting in a net margin of 50.5%.
Frequently Asked Questions
MDGL and TSM have a correlation of 0.09, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
MDGL has higher volatility (13.71%) compared to TSM (13.42%). In terms of maximum drawdown, MDGL dropped -98.40% vs TSM's -89.08%.
TSM currently has the higher Sharpe Ratio (2.71 vs 1.35), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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