MCK vs. ISRG
MCK (McKesson Corporation) and ISRG (Intuitive Surgical, Inc.) are both stocks. Both are in the Healthcare sector — MCK in Medical Distribution, ISRG in Medical Instruments & Supplies. Over the past 10 years, MCK returned 16.64%/yr vs 19.09%/yr for ISRG. At a 0.28 correlation, their price movements are largely independent.
Performance
MCK vs. ISRG - Performance Comparison
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Returns By Period
In the year-to-date period, MCK achieves a -4.23% return, which is significantly higher than ISRG's -27.42% return. Over the past 10 years, MCK has underperformed ISRG with an annualized return of 16.64%, while ISRG has yielded a comparatively higher 19.09% annualized return.
MCK
- 1D
- -0.40%
- 1M
- 3.20%
- YTD
- -4.23%
- 6M
- -3.47%
- 1Y
- 8.11%
- 3Y*
- 26.04%
- 5Y*
- 32.74%
- 10Y*
- 16.64%
ISRG
- 1D
- -0.45%
- 1M
- -2.39%
- YTD
- -27.42%
- 6M
- -24.20%
- 1Y
- -19.74%
- 3Y*
- 9.23%
- 5Y*
- 7.37%
- 10Y*
- 19.09%
MCK vs. ISRG - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
MCK McKesson Corporation | -4.23% | 44.54% | 23.67% | 24.13% | 51.82% | 44.23% | 27.06% | 26.72% | -28.40% | 11.95% |
ISRG Intuitive Surgical, Inc. | -27.42% | 8.51% | 54.72% | 27.14% | -26.15% | 31.76% | 38.39% | 23.43% | 31.23% | 72.64% |
Correlation
The correlation between MCK and ISRG is 0.16, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.16 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.14 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.20 |
Correlation (10Y) Calculated over the trailing 10-year period | 0.26 |
Correlation (All Time) Calculated using the full available price history since Jun 16, 2000 | 0.28 |
The correlation between MCK and ISRG shifts across timeframes, from 0.14 (3 years) to 0.28 (all time), reflecting how their relationship changes across market environments.
Fundamentals
MCK:
$96.20B
ISRG:
$147.90B
MCK:
$38.38
ISRG:
$8.24
MCK:
20.43
ISRG:
49.88
MCK:
0.27
ISRG:
3.05
MCK:
0.24
ISRG:
14.04
MCK:
13.91
ISRG:
8.40
MCK:
$403.43B
ISRG:
$10.58B
MCK:
$14.55B
ISRG:
$7.02B
MCK:
$6.91B
ISRG:
$3.76B
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Return for Risk
MCK vs. ISRG — Risk / Return Rank
MCK
ISRG
MCK vs. ISRG - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for McKesson Corporation (MCK) and Intuitive Surgical, Inc. (ISRG). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| MCK | ISRG | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +0.92 | ||
| Sortino ratioReturn per unit of downside risk | +1.50 | ||
| Omega ratioGain probability vs. loss probability | 1.08 | 0.90 | +0.18 |
| Calmar ratioReturn relative to maximum drawdown | 0.29 | -0.62 | +0.91 |
| Martin ratioReturn relative to average drawdown | 0.74 | -1.24 | +1.99 |
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Drawdowns
MCK vs. ISRG - Drawdown Comparison
The maximum MCK drawdown since its inception was -82.84%, roughly equal to the maximum ISRG drawdown of -82.26%. Use the drawdown chart below to compare losses from any high point for MCK and ISRG.
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Drawdown Indicators
| MCK | ISRG | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -82.84% | -82.26% | -0.58% |
Max Drawdown (1Y)Largest decline over 1 year | -27.17% | -32.14% | +4.97% |
Max Drawdown (3Y)Largest decline over 3 years | -27.17% | -34.10% | +6.93% |
Max Drawdown (5Y)Largest decline over 5 years | -27.17% | -49.90% | +22.73% |
Max Drawdown (10Y)Largest decline over 10 years | -44.23% | -49.90% | +5.67% |
Current DrawdownCurrent decline from peak | -21.17% | -32.66% | +11.49% |
Average DrawdownAverage peak-to-trough decline | -28.64% | -21.28% | -7.36% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 10.40% | 16.00% | -5.60% |
Volatility
MCK vs. ISRG - Volatility Comparison
The current volatility for McKesson Corporation (MCK) is 6.47%, while Intuitive Surgical, Inc. (ISRG) has a volatility of 9.70%. This indicates that MCK experiences smaller price fluctuations and is considered to be less risky than ISRG based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| MCK | ISRG | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 6.47% | 9.70% | -3.23% |
Volatility (6M)Calculated over the trailing 6-month period | 22.74% | 20.72% | +2.02% |
Volatility (1Y)Calculated over the trailing 1-year period | 29.14% | 30.69% | -1.55% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 24.19% | 33.19% | -9.00% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 28.82% | 32.40% | -3.58% |
Dividends
MCK vs. ISRG - Dividend Comparison
MCK's dividend yield for the trailing twelve months is around 0.42%, while ISRG has not paid dividends to shareholders.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
ISRG Intuitive Surgical, Inc. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
MCK McKesson Corporation | 0.42% | 0.37% | 0.47% | 0.50% | 0.54% | 0.72% | 0.95% | 1.16% | 1.32% | 0.80% | 0.80% | 0.53% |
Financials
MCK vs. ISRG - Financials Comparison
This section allows you to compare key financial metrics between McKesson Corporation and Intuitive Surgical, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
MCK vs. ISRG - Profitability Comparison
MCK - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, McKesson Corporation reported a gross profit of 4.04B and revenue of 96.30B. Therefore, the gross margin over that period was 4.2%.
ISRG - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Intuitive Surgical, Inc. reported a gross profit of 1.83B and revenue of 2.77B. Therefore, the gross margin over that period was 66.1%.
MCK - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, McKesson Corporation reported an operating income of 2.09B and revenue of 96.30B, resulting in an operating margin of 2.2%.
ISRG - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Intuitive Surgical, Inc. reported an operating income of 855.30M and revenue of 2.77B, resulting in an operating margin of 30.9%.
MCK - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, McKesson Corporation reported a net income of 1.68B and revenue of 96.30B, resulting in a net margin of 1.8%.
ISRG - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Intuitive Surgical, Inc. reported a net income of 821.50M and revenue of 2.77B, resulting in a net margin of 29.7%.
Frequently Asked Questions
MCK and ISRG have a correlation of 0.16, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
ISRG has higher volatility (9.70%) compared to MCK (6.47%). In terms of maximum drawdown, MCK dropped -82.84% vs ISRG's -82.26%.
MCK currently has the higher Sharpe Ratio (0.27 vs -0.65), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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