JNGLX vs. LYFIX
Compare and contrast key facts about Janus Henderson Global Life Sciences Fund (JNGLX) and AlphaCentric LifeSci Healthcare Fund (LYFIX).
JNGLX is managed by Janus Henderson. It was launched on Dec 30, 1998. LYFIX is managed by AlphaCentric Funds. It was launched on Nov 28, 2019.
Performance
JNGLX vs. LYFIX - Performance Comparison
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JNGLX vs. LYFIX - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | |
|---|---|---|---|---|---|---|---|---|
JNGLX Janus Henderson Global Life Sciences Fund | -3.73% | 24.84% | 3.60% | 7.51% | -2.69% | 6.78% | 25.66% | 4.08% |
LYFIX AlphaCentric LifeSci Healthcare Fund | -0.31% | 28.22% | -0.27% | 7.19% | -0.92% | -3.42% | 54.83% | 1.20% |
Returns By Period
In the year-to-date period, JNGLX achieves a -3.73% return, which is significantly lower than LYFIX's -0.31% return.
JNGLX
- 1D
- 3.08%
- 1M
- -5.55%
- YTD
- -3.73%
- 6M
- 11.88%
- 1Y
- 21.71%
- 3Y*
- 10.69%
- 5Y*
- 7.33%
- 10Y*
- 11.02%
LYFIX
- 1D
- 4.07%
- 1M
- -3.00%
- YTD
- -0.31%
- 6M
- 16.38%
- 1Y
- 26.02%
- 3Y*
- 8.51%
- 5Y*
- 4.83%
- 10Y*
- —
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JNGLX vs. LYFIX - Expense Ratio Comparison
JNGLX has a 0.80% expense ratio, which is lower than LYFIX's 1.40% expense ratio.
Return for Risk
JNGLX vs. LYFIX — Risk / Return Rank
JNGLX
LYFIX
JNGLX vs. LYFIX - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Janus Henderson Global Life Sciences Fund (JNGLX) and AlphaCentric LifeSci Healthcare Fund (LYFIX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| JNGLX | LYFIX | Difference | |
|---|---|---|---|
Sharpe ratioReturn per unit of total volatility | 1.07 | 1.25 | -0.18 |
Sortino ratioReturn per unit of downside risk | 1.54 | 1.79 | -0.25 |
Omega ratioGain probability vs. loss probability | 1.20 | 1.22 | -0.02 |
Calmar ratioReturn relative to maximum drawdown | 1.80 | 2.36 | -0.56 |
Martin ratioReturn relative to average drawdown | 4.97 | 5.75 | -0.77 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| JNGLX | LYFIX | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 1.07 | 1.25 | -0.18 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | 0.47 | 0.21 | +0.26 |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | 0.63 | — | — |
Sharpe Ratio (All Time)Calculated using the full available price history | 0.57 | 0.51 | +0.06 |
Correlation
The correlation between JNGLX and LYFIX is 0.80, which is considered to be high. That indicates a strong positive relationship between their price movements. Having highly-correlated positions in a portfolio may signal a lack of diversification, potentially leading to increased risk during market downturns.
Dividends
JNGLX vs. LYFIX - Dividend Comparison
JNGLX's dividend yield for the trailing twelve months is around 4.74%, more than LYFIX's 1.79% yield.
| TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
JNGLX Janus Henderson Global Life Sciences Fund | 4.74% | 4.56% | 5.84% | 4.26% | 0.25% | 9.85% | 7.80% | 6.23% | 13.32% | 0.89% | 0.30% | 8.81% |
LYFIX AlphaCentric LifeSci Healthcare Fund | 1.79% | 1.78% | 2.24% | 2.63% | 4.43% | 12.88% | 2.30% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
Drawdowns
JNGLX vs. LYFIX - Drawdown Comparison
The maximum JNGLX drawdown since its inception was -59.00%, which is greater than LYFIX's maximum drawdown of -35.33%. Use the drawdown chart below to compare losses from any high point for JNGLX and LYFIX.
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Drawdown Indicators
| JNGLX | LYFIX | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -59.00% | -35.33% | -23.67% |
Max Drawdown (1Y)Largest decline over 1 year | -9.68% | -9.47% | -0.21% |
Max Drawdown (5Y)Largest decline over 5 years | -22.21% | -32.45% | +10.24% |
Max Drawdown (10Y)Largest decline over 10 years | -27.37% | — | — |
Current DrawdownCurrent decline from peak | -6.62% | -3.88% | -2.74% |
Average DrawdownAverage peak-to-trough decline | -17.73% | -10.07% | -7.66% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 3.61% | 4.24% | -0.63% |
Volatility
JNGLX vs. LYFIX - Volatility Comparison
The current volatility for Janus Henderson Global Life Sciences Fund (JNGLX) is 5.98%, while AlphaCentric LifeSci Healthcare Fund (LYFIX) has a volatility of 7.96%. This indicates that JNGLX experiences smaller price fluctuations and is considered to be less risky than LYFIX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| JNGLX | LYFIX | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 5.98% | 7.96% | -1.98% |
Volatility (6M)Calculated over the trailing 6-month period | 10.63% | 13.70% | -3.07% |
Volatility (1Y)Calculated over the trailing 1-year period | 17.86% | 19.38% | -1.52% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 15.69% | 22.93% | -7.24% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 17.42% | 23.50% | -6.08% |