- ISIN
- US47103E7004
- Issuer
- Janus Henderson
- Inception Date
- Dec 30, 1998
- Category
- Health & Biotech Equities
- Min. Investment
- $2,500
- Distribution Policy
- Distributing
- Asset Class
- Equity
- Asset Class Size
- Large-Cap
- Asset Class Style
- Blend
Share Price Chart
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Performance
JNGLX Performance Chart
Janus Henderson Global Life Sciences Fund (JNGLX) is up 0.6% since the beginning of the year. JNGLX is currently trading at $81 per share. Investors who bought $1,000 worth of JNGLX shares 5 years ago would now be looking at an investment worth $1,414.
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Returns By Period
Janus Henderson Global Life Sciences Fund (JNGLX) has returned 0.58% so far this year and 31.21% over the past 12 months. Over the last ten years, JNGLX has returned 11.16% per year, falling short of the S&P 500 Index benchmark, which averaged 13.88% annually.
Janus Henderson Global Life Sciences Fund
- 1D
- -0.40%
- 1M
- 0.72%
- YTD
- 0.58%
- 6M
- 0.05%
- 1Y
- 31.21%
- 3Y*
- 10.25%
- 5Y*
- 7.18%
- 10Y*
- 11.16%
Benchmark (S&P 500 Index)
- 1D
- -0.37%
- 1M
- -0.01%
- YTD
- 9.16%
- 6M
- 8.64%
- 1Y
- 25.22%
- 3Y*
- 19.78%
- 5Y*
- 11.99%
- 10Y*
- 13.88%
JNGLX Monthly Returns History
Based on dividend-adjusted daily data since Jan 4, 1999, JNGLX's average daily return is +0.05%, while the average monthly return is +1.04%. At this rate, an investment would double in approximately 5.6 years.
Historically, 62% of months were positive and 38% were negative. The best month was Feb 2000 with a return of +40.8%, while the worst month was Mar 2000 at -29.5%. The longest winning streak lasted 15 consecutive months, and the longest losing streak was 6 months.
On a daily basis, JNGLX closed higher 53% of trading days. The best single day was Oct 13, 2008 with a return of +11.7%, while the worst single day was Mar 16, 2020 at -10.4%.
| Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec | Total | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026 | 0.78% | 2.06% | -6.40% | 1.82% | 2.43% | 0.17% | 0.58% | ||||||
| 2025 | 5.94% | -0.21% | -4.47% | -0.29% | -5.69% | 2.33% | -0.85% | 6.13% | 2.88% | 8.71% | 9.27% | -0.10% | 24.84% |
| 2024 | 2.76% | 3.84% | 1.74% | -4.65% | 3.56% | 3.22% | 2.67% | 5.17% | -2.41% | -3.28% | -0.71% | -7.49% | 3.60% |
| 2023 | 0.49% | -4.32% | 2.68% | 4.04% | -2.32% | 3.00% | 1.02% | -1.40% | -3.74% | -6.10% | 7.42% | 7.58% | 7.51% |
| 2022 | -9.04% | 0.59% | 3.58% | -6.71% | -0.91% | -0.76% | 3.65% | -2.53% | -2.88% | 8.55% | 6.02% | -0.89% | -2.69% |
| 2021 | -0.84% | 0.08% | -1.92% | 3.12% | 0.25% | 3.59% | 0.15% | 3.21% | -4.07% | 4.49% | -7.39% | 6.76% | 6.78% |
Benchmark Metrics
Janus Henderson Global Life Sciences Fund has an annualized alpha of 6.27%, beta of 0.77, and R2 of 0.57 versus S&P 500 Index. Calculated based on daily prices since January 04, 1999.
- This fund participates in less of S&P 500 Index's moves in both directions, but captures a larger share of gains (85.52%) than losses (65.04%) - typical of diversified or defensive assets.
- This fund generated an annualized alpha of 6.27% versus S&P 500 Index - delivering returns beyond what market exposure alone would predict.
- Alpha
- 6.27%
- Beta
- 0.77
- R²
- 0.57
- Upside Capture
- 85.52%
- Downside Capture
- 65.04%
Expense Ratio
JNGLX has an expense ratio of 0.80%, placing it in the medium range.
Return for Risk
Risk / Return Rank
JNGLX ranks 59 for risk / return — on par with similar mutual funds. You're getting a typical balance of risk and reward. Not a standout, but not a red flag either — a reasonable choice if other factors align with your goals.
Return / Risk — by metrics
The table below present risk-adjusted performance metrics for Janus Henderson Global Life Sciences Fund (JNGLX) and compare them to S&P 500 Index.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| JNGLX | Benchmark | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +0.01 | ||
| Sortino ratioReturn per unit of downside risk | +0.23 | ||
| Omega ratioGain probability vs. loss probability | 1.36 | 1.37 | -0.01 |
| Calmar ratioReturn relative to maximum drawdown | 3.19 | 2.78 | +0.41 |
| Martin ratioReturn relative to average drawdown | 10.17 | 12.44 | -2.26 |
Dividends
Dividend History
Janus Henderson Global Life Sciences Fund provided a 4.54% dividend yield over the last twelve months, with an annual payout of $3.70 per share.
| Period | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dividend | $3.70 | $3.70 | $3.96 | $2.94 | $0.17 | $6.82 | $5.57 | $3.82 | $6.72 | $0.48 | $0.13 | $4.60 |
Dividend yield | 4.54% | 4.56% | 5.84% | 4.26% | 0.25% | 9.85% | 7.80% | 6.23% | 13.32% | 0.89% | 0.30% | 8.81% |
Monthly Dividends
The table displays the monthly dividend distributions for Janus Henderson Global Life Sciences Fund. The dividends shown in the table have been adjusted to account for any splits that may have occurred.
| Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec | Total | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | ||||||
| 2025 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $3.70 | $3.70 |
| 2024 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $3.96 | $3.96 |
| 2023 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $2.94 | $2.94 |
| 2022 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.17 | $0.17 |
| 2021 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $6.82 | $6.82 |
Drawdowns
Drawdowns Chart
The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.
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Worst Drawdowns
The table below displays the maximum drawdowns of the Janus Henderson Global Life Sciences Fund. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.
The maximum drawdown for the Janus Henderson Global Life Sciences Fund was 59.00%, occurring on Feb 13, 2003. Recovery took 2294 trading sessions.
The current Janus Henderson Global Life Sciences Fund drawdown is 2.44%.
Related event | Drawdown | Fall | Recovery | Underwater |
|---|---|---|---|---|
2003 bear market2003 | -59.00%Feb 2003 | 2y 11mo | 9y 1mo | 12y 20dMar 2000 - Mar 2012 |
2016 bear market2016 | -31.04%Feb 2016 | 6mo 22d | 1y 11mo | 2y 6moJul 2015 - Jan 2018 |
COVID crash2020 | -27.37%Mar 2020 | 1mo 2d | 2mo 11d | 3mo 13dFeb 2020 - Jun 2020 |
Bear market2022 | -22.21%Jun 2022 | 7mo 14d | 1y 6mo | 2y 1moNov 2021 - Dec 2023 |
2025 selloff2025 | -21.17%Apr 2025 | 7mo 7d | 7mo 6d | 1y 2moSep 2024 - Nov 2025 |
Drawdown Indicators
| JNGLX | Benchmark | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -59.00% | -56.78% | -2.22% |
Max Drawdown (1Y)Largest decline over 1 year | -9.68% | -9.10% | -0.58% |
Max Drawdown (3Y)Largest decline over 3 years | -21.17% | -18.90% | -2.27% |
Max Drawdown (5Y)Largest decline over 5 years | -22.21% | -25.43% | +3.22% |
Max Drawdown (10Y)Largest decline over 10 years | -27.37% | -33.92% | +6.55% |
Current DrawdownCurrent decline from peak | -2.44% | -1.80% | -0.64% |
Average DrawdownAverage peak-to-trough decline | -17.62% | -10.71% | -6.91% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 3.03% | 2.03% | +1.00% |
Volatility
Volatility Chart
The chart below shows the rolling one-month volatility.
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