INSM vs. SAN
INSM (Insmed Incorporated) and SAN (Banco Santander, S.A.) are both stocks. INSM operates in Biotechnology (Healthcare), while SAN operates in Banks - Diversified (Financial Services). Over the past 10 years, INSM returned 26.59%/yr vs 18.20%/yr for SAN. At a 0.16 correlation, their price movements are largely independent.
Performance
INSM vs. SAN - Performance Comparison
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Returns By Period
In the year-to-date period, INSM achieves a -38.74% return, which is significantly lower than SAN's 19.10% return. Over the past 10 years, INSM has outperformed SAN with an annualized return of 26.59%, while SAN has yielded a comparatively lower 18.20% annualized return.
INSM
- 1D
- 1.79%
- 1M
- -0.27%
- YTD
- -38.74%
- 6M
- -38.76%
- 1Y
- 5.94%
- 3Y*
- 71.60%
- 5Y*
- 29.33%
- 10Y*
- 26.59%
SAN
- 1D
- 1.10%
- 1M
- 10.58%
- YTD
- 19.10%
- 6M
- 17.99%
- 1Y
- 70.52%
- 3Y*
- 60.56%
- 5Y*
- 33.06%
- 10Y*
- 18.20%
INSM vs. SAN - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
INSM Insmed Incorporated | -38.74% | 152.09% | 122.78% | 55.11% | -26.65% | -18.17% | 39.41% | 82.01% | -57.92% | 135.68% |
SAN Banco Santander, S.A. | 19.10% | 164.72% | 14.96% | 46.20% | -6.62% | 10.41% | -21.99% | -2.32% | -28.49% | 32.28% |
Correlation
The correlation between INSM and SAN is 0.14, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.14 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.13 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.19 |
Correlation (10Y) Calculated over the trailing 10-year period | 0.20 |
Correlation (All Time) Calculated using the full available price history since Jun 1, 2000 | 0.16 |
Fundamentals
INSM:
$22.97B
SAN:
$202.56B
INSM:
-$5.54
SAN:
€1.05
INSM:
27.78
SAN:
2.49
INSM:
32.59
SAN:
1.67
INSM:
$819.56M
SAN:
€74.92B
INSM:
$668.55M
SAN:
€46.97B
INSM:
-$1.14B
SAN:
€21.14B
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Return for Risk
INSM vs. SAN — Risk / Return Rank
INSM
SAN
INSM vs. SAN - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Insmed Incorporated (INSM) and Banco Santander, S.A. (SAN). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| INSM | SAN | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -2.05 | ||
| Sortino ratioReturn per unit of downside risk | -2.32 | ||
| Omega ratioGain probability vs. loss probability | 1.08 | 1.34 | -0.26 |
| Calmar ratioReturn relative to maximum drawdown | 0.11 | 3.49 | -3.39 |
| Martin ratioReturn relative to average drawdown | 0.23 | 10.78 | -10.55 |
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Drawdowns
INSM vs. SAN - Drawdown Comparison
The maximum INSM drawdown since its inception was -98.65%, which is greater than SAN's maximum drawdown of -82.94%. Use the drawdown chart below to compare losses from any high point for INSM and SAN.
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Drawdown Indicators
| INSM | SAN | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -98.65% | -82.94% | -15.71% |
Max Drawdown (1Y)Largest decline over 1 year | -56.54% | -20.29% | -36.25% |
Max Drawdown (3Y)Largest decline over 3 years | -56.54% | -20.29% | -36.25% |
Max Drawdown (5Y)Largest decline over 5 years | -56.54% | -40.82% | -15.72% |
Max Drawdown (10Y)Largest decline over 10 years | -64.84% | -73.84% | +9.00% |
Current DrawdownCurrent decline from peak | -49.57% | 0.00% | -49.57% |
Average DrawdownAverage peak-to-trough decline | -86.02% | -30.62% | -55.40% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 26.03% | 6.56% | +19.47% |
Volatility
INSM vs. SAN - Volatility Comparison
Insmed Incorporated (INSM) has a higher volatility of 17.20% compared to Banco Santander, S.A. (SAN) at 8.97%. This indicates that INSM's price experiences larger fluctuations and is considered to be riskier than SAN based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| INSM | SAN | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 17.20% | 8.97% | +8.23% |
Volatility (6M)Calculated over the trailing 6-month period | 42.95% | 27.63% | +15.32% |
Volatility (1Y)Calculated over the trailing 1-year period | 52.07% | 32.71% | +19.36% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 72.85% | 33.88% | +38.97% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 78.41% | 35.18% | +43.23% |
Dividends
INSM vs. SAN - Dividend Comparison
INSM has not paid dividends to shareholders, while SAN's dividend yield for the trailing twelve months is around 2.03%.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
INSM Insmed Incorporated | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
SAN Banco Santander, S.A. | 2.03% | 2.11% | 4.63% | 3.58% | 3.83% | 2.71% | 0.00% | 6.20% | 5.83% | 4.60% | 3.29% | 7.06% |
Financials
INSM vs. SAN - Financials Comparison
This section allows you to compare key financial metrics between Insmed Incorporated and Banco Santander, S.A.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
INSM vs. SAN - Profitability Comparison
INSM - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jul 2026, Insmed Incorporated reported a gross profit of 258.54M and revenue of 305.96M. Therefore, the gross margin over that period was 84.5%.
SAN - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jul 2026, Banco Santander, S.A. reported a gross profit of 12.95B and revenue of 31.44B. Therefore, the gross margin over that period was 41.2%.
INSM - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jul 2026, Insmed Incorporated reported an operating income of -198.20M and revenue of 305.96M, resulting in an operating margin of -64.8%.
SAN - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jul 2026, Banco Santander, S.A. reported an operating income of 5.11B and revenue of 31.44B, resulting in an operating margin of 16.3%.
INSM - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jul 2026, Insmed Incorporated reported a net income of -163.56M and revenue of 305.96M, resulting in a net margin of -53.5%.
SAN - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jul 2026, Banco Santander, S.A. reported a net income of 5.54B and revenue of 31.44B, resulting in a net margin of 17.6%.
Frequently Asked Questions
INSM and SAN have a correlation of 0.14, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
INSM has higher volatility (17.20%) compared to SAN (8.97%). In terms of maximum drawdown, INSM dropped -98.65% vs SAN's -82.94%.
SAN currently has the higher Sharpe Ratio (2.17 vs 0.11), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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