INSM vs. VRNA

Last updated Apr 1, 2026

Compare and contrast key facts about Insmed Incorporated (INSM) and Verona Pharma plc (VRNA).

Performance

INSM vs. VRNA - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Insmed Incorporated (INSM) and Verona Pharma plc (VRNA). The values are adjusted to include any dividend payments, if applicable.

INSM vs. VRNA - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
INSM Insmed Incorporated	-6.04%	152.09%	122.78%	55.11%	-26.65%	-18.17%	39.41%	82.01%	-57.92%	66.12%
VRNA Verona Pharma plc	0.00%	130.21%	133.60%	-23.92%	288.84%	-4.00%	21.74%	-40.41%	-18.71%	-12.07%

Fundamentals

Market Cap INSM : $34.93B VRNA : $9.72B
EPS INSM : -$6.23 VRNA : -$0.69
PS Ratio INSM : 55.22 VRNA : 57.97
PB Ratio INSM : 47.27 VRNA : 34.92
Total Revenue (TTM) INSM : $606.42M VRNA : $167.65M
Gross Profit (TTM) INSM : $483.49M VRNA : $159.52M
EBITDA (TTM) INSM : -$1.19B VRNA : -$40.86M

Returns By Period

INSM

• 1D: 6.65%
• 1M: 9.50%
• YTD: -6.04%
• 6M: 13.55%
• 1Y: 114.34%
• 3Y*: 112.46%
• 5Y*: 35.77%
• 10Y*: 29.16%

VRNA

• 1D: —
• 1M: —
• YTD: —
• 6M: —
• 1Y: —
• 3Y*: —
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

INSM vs. VRNA — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

INSM

INSM Risk / Return Rank: 89
INSM Sharpe Ratio Rank: 92
INSM Sortino Ratio Rank: 92
INSM Omega Ratio Rank: 92
INSM Calmar Ratio Rank: 87
INSM Martin Ratio Rank: 84

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

INSM vs. VRNA - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Insmed Incorporated (INSM) and Verona Pharma plc (VRNA). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	INSM	VRNA	Difference
Sharpe ratio Return per unit of total volatility	2.16	—	—
Sortino ratio Return per unit of downside risk	3.03	—	—
Omega ratio Gain probability vs. loss probability	1.42	—	—
Calmar ratio Return relative to maximum drawdown	3.07	—	—
Martin ratio Return relative to average drawdown	7.39	—	—
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

Sharpe Ratios by Period

	INSM	VRNA	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	2.16	—	—
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.50	—	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.37	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.00	—	—

Correlation

The correlation between INSM and VRNA is 0.19, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

INSM vs. VRNA - Dividend Comparison

Neither INSM nor VRNA has paid dividends to shareholders.

Tickers have no history of dividend payments

Drawdowns

Drawdown Indicators

	INSM	VRNA	Difference
Max Drawdown Largest peak-to-trough decline	-98.65%	—	—
Max Drawdown (1Y) Largest decline over 1 year	-35.67%	—	—
Max Drawdown (5Y) Largest decline over 5 years	-54.85%	—	—
Max Drawdown (10Y) Largest decline over 10 years	-64.84%	—	—
Current Drawdown Current decline from peak	-22.65%	—	—
Average Drawdown Average peak-to-trough decline	-86.44%	—	—
Ulcer Index Depth and duration of drawdowns from previous peaks	14.84%	—	—

Volatility

Volatility by Period

	INSM	VRNA	Difference
Volatility (1M) Calculated over the trailing 1-month period	15.95%	—	—
Volatility (6M) Calculated over the trailing 6-month period	35.51%	—	—
Volatility (1Y) Calculated over the trailing 1-year period	53.23%	—	—
Volatility (5Y) Calculated over the trailing 5-year period, annualized	72.40%	—	—
Volatility (10Y) Calculated over the trailing 10-year period, annualized	78.16%	—	—

Financials