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ISIN
US4576693075
CUSIP
457669307
IPO Date
Jun 1, 2000

Highlights

Market Cap
$21.25B
Enterprise Value
$20.71B
EPS (TTM)
-$5.71
Total Revenue (TTM)
$819.56M
Gross Profit (TTM)
$668.55M
EBITDA (TTM)
-$1.14B
Year Range
$90.39 - $212.75
Target Price
$217.11
ROA (TTM)
-57.02%
ROE (TTM)
-167.94%

Share Price Chart


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Performance

INSM Performance Chart

Insmed Incorporated (INSM) is down 43.3% since the beginning of the year. At $99 per share, INSM is trading 53.7% below its 52-week high of $213. Investors who bought $1,000 worth of INSM shares 5 years ago would now be looking at an investment worth $3,542.


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S&P 500 Index

Returns By Period

Insmed Incorporated (INSM) has returned -43.34% so far this year and -3.97% over the past 12 months. Looking at the last ten years, INSM has achieved an annualized return of 26.23%, outperforming the S&P 500 Index benchmark, which averaged 13.88% per year.


Insmed Incorporated

1D
2.93%
1M
-7.19%
YTD
-43.34%
6M
-43.90%
1Y
-3.97%
3Y*
70.31%
5Y*
28.78%
10Y*
26.23%

Benchmark (S&P 500 Index)

1D
-0.37%
1M
-0.01%
YTD
9.16%
6M
8.64%
1Y
25.22%
3Y*
19.78%
5Y*
11.99%
10Y*
13.88%
*Multi-year figures are annualized to reflect compound growth (CAGR)

INSM Monthly Returns History

Based on dividend-adjusted daily data since Jun 1, 2000, INSM's average daily return is +0.13%, while the average monthly return is +2.91%. At this rate, an investment would double in approximately 2.0 years.

Historically, 49% of months were positive and 51% were negative. The best month was Sep 2017 with a return of +151.3%, while the worst month was Sep 2002 at -77.8%. The longest winning streak lasted 6 consecutive months, and the longest losing streak was 7 months.

On a daily basis, INSM closed higher 47% of trading days. The best single day was Sep 5, 2017 with a return of +119.6%, while the worst single day was Sep 10, 2002 at -70.2%.


JanFebMarAprMayJunJulAugSepOctNovDecTotal
2026-9.87%-4.81%9.50%-16.63%-21.58%-7.77%-43.34%
202510.92%6.49%-6.45%-5.62%-3.15%44.33%6.60%26.86%5.81%31.66%9.58%-16.23%152.09%
2024-10.29%-0.29%-2.13%-8.88%122.69%21.71%8.58%5.11%-4.54%-7.84%11.71%-8.14%122.78%
20237.76%-5.34%-16.34%14.37%-2.41%10.88%4.69%-0.91%15.35%-0.75%-0.16%23.86%55.11%
2022-16.74%5.38%-1.67%-6.51%-14.34%4.78%12.17%11.30%-12.51%-19.59%6.76%8.06%-26.65%
202112.92%-4.84%-4.78%-0.97%-27.07%15.69%-13.56%13.98%-1.78%9.48%-8.72%-1.02%-18.17%

Benchmark Metrics

Insmed Incorporated has an annualized alpha of 29.87%, beta of 0.93, and R2 of 0.04 versus S&P 500 Index. Calculated based on daily prices since June 01, 2000.

  • This stock participated in 149.23% of S&P 500 Index downside but only 124.36% of its upside - more exposed to losses than it benefited from rallies.
  • R2 of 0.04 means this stock moves largely independently of S&P 500 Index - capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.

Alpha
29.87%
Beta
0.93
0.04
Upside Capture
124.36%
Downside Capture
149.23%

Return for Risk

Risk / Return Rank

INSM ranks 39 for risk / return — below 39% of stocks on our site. The returns aren't fully compensating for the risk involved. This isn't necessarily a dealbreaker, but factor it into your decision — especially if you're risk-averse.


INSM Risk / Return Rank: 3939
Overall Rank
INSM Sharpe Ratio Rank: 3939
Sharpe Ratio Rank
INSM Sortino Ratio Rank: 3838
Sortino Ratio Rank
INSM Omega Ratio Rank: 3838
Omega Ratio Rank
INSM Calmar Ratio Rank: 4040
Calmar Ratio Rank
INSM Martin Ratio Rank: 3939
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

Return / Risk — by metrics

The table below present risk-adjusted performance metrics for Insmed Incorporated (INSM) and compare them to S&P 500 Index.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.


INSMBenchmarkDifference
Sharpe ratioReturn per unit of total volatility

-2.11

Sortino ratioReturn per unit of downside risk

-2.50

Omega ratioGain probability vs. loss probability

1.04

1.37

-0.33

Calmar ratioReturn relative to maximum drawdown

-0.07

2.78

-2.85

Martin ratioReturn relative to average drawdown

-0.16

12.44

-12.60

Dividends

Dividend History


Insmed Incorporated doesn't pay dividends

Drawdowns

Drawdowns Chart

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.


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Worst Drawdowns

The table below displays the maximum drawdowns of the Insmed Incorporated. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the Insmed Incorporated was 98.65%, occurring on Nov 25, 2011. Recovery took 3514 trading sessions.

The current Insmed Incorporated drawdown is 53.36%.


Related event

Drawdown

Fall

Recovery

Underwater

2011 bear market2011
-98.65%Nov 2011
11y 2mo13y 12mo
25y 2moAug 2000 - Nov 2025
2026 bear market2026
-56.54%Jun 2026
6mo 10d
6mo 23dDec 2025 - now
Dot-com crash2000–2002
-35.29%Jul 2000
1mo 4d24d
1mo 28dJun 2000 - Aug 2000
Dot-com crash2000–2002
-28.69%Aug 2000
13d11d
24dAug 2000 - Aug 2000
Dot-com crash2000–2002
-2.91%Jun 2000
0s3d
3dJun 2000 - Jun 2000

Drawdown Indicators


INSMBenchmarkDifference

Max Drawdown

Largest peak-to-trough decline

-98.65%

-56.78%

-41.87%

Max Drawdown (1Y)

Largest decline over 1 year

-56.54%

-9.10%

-47.44%

Max Drawdown (3Y)

Largest decline over 3 years

-56.54%

-18.90%

-37.64%

Max Drawdown (5Y)

Largest decline over 5 years

-56.54%

-25.43%

-31.11%

Max Drawdown (10Y)

Largest decline over 10 years

-64.84%

-33.92%

-30.92%

Current Drawdown

Current decline from peak

-53.36%

-1.80%

-51.56%

Average Drawdown

Average peak-to-trough decline

-86.05%

-10.71%

-75.34%

Ulcer Index

Depth and duration of drawdowns from previous peaks

24.87%

2.03%

+22.84%

Volatility

Volatility Chart

The chart below shows the rolling one-month volatility.


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Financials

Financial Performance

The chart below illustrates the trends in the financial health of Insmed Incorporated over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.


Annual
Quarterly

0.0

Valuation

The Valuation section provides an overview of how Insmed Incorporated is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.


PS Ratio

This chart shows the Price-to-Sales (P/S) ratio for INSM relative to other companies in the Biotechnology industry. Currently, INSM has a P/S ratio of 25.0. This P/S ratio falls within the average range for the industry, suggesting the stock is fairly valued based on its revenue.

PB Ratio

The chart illustrates the Price-to-Book (P/B) ratio for INSM in comparison with other companies in the Biotechnology industry. Currently, INSM has a P/B value of 30.1. This P/B ratio is higher than most companies in the industry. It may suggest the stock is overvalued or that investors expect the company to generate high returns on its assets.

Income Statement



TTM
Revenue

Total Revenue

Cost Of Revenue

Gross Profit

Operating Expenses

Selling, General & Admin Expenses

R&D Expenses

Depreciation And Amortization

Total Operating Expenses

Income

Income Before Tax

Operating Income

EBITDA

EBIT

Earnings From Continuing Operations

Net Income

Income Tax Expense

Other Non-Operating Income (Expenses)

Extraordinary Items

Discontinued Operations

Effect Of Accounting Charges

Non Recurring

Minority Interest

Other Items

Interest Income

Interest Expense

Net Interest Income

Values in undefined except per share items
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