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INCY vs. INSM
Performance
Return for Risk
Drawdowns
Volatility
Dividends
Financials

Performance

INCY vs. INSM - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Incyte Corporation (INCY) and Insmed Incorporated (INSM). The values are adjusted to include any dividend payments, if applicable.

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Returns By Period

In the year-to-date period, INCY achieves a -0.80% return, which is significantly higher than INSM's -40.32% return. Over the past 10 years, INCY has underperformed INSM with an annualized return of 1.44%, while INSM has yielded a comparatively higher 24.16% annualized return.


INCY

1D
6.22%
1M
0.86%
YTD
-0.80%
6M
-3.47%
1Y
46.00%
3Y*
16.14%
5Y*
3.29%
10Y*
1.44%

INSM

1D
0.13%
1M
-25.82%
YTD
-40.32%
6M
-49.77%
1Y
42.12%
3Y*
74.52%
5Y*
32.61%
10Y*
24.16%
*Multi-year figures are annualized to reflect compound growth (CAGR)

INCY vs. INSM - Yearly Performance Comparison


2026 (YTD)202520242023202220212020201920182017
INCY
Incyte Corporation
-0.80%43.00%10.00%-21.83%9.43%-15.61%-0.39%37.32%-32.86%-5.55%
INSM
Insmed Incorporated
-40.32%152.09%122.78%55.11%-26.65%-18.17%39.41%82.01%-57.92%135.68%

Correlation

The correlation between INCY and INSM is 0.25, which is low. Their price movements are largely independent, making them effective diversification partners.


Correlation
Correlation (1Y)
Calculated over the trailing 1-year period

0.25

Correlation (3Y)
Calculated over the trailing 3-year period

0.24

Correlation (5Y)
Calculated over the trailing 5-year period

0.33

Correlation (10Y)
Calculated over the trailing 10-year period

0.37

Correlation (All Time)
Calculated using the full available price history since Jun 2, 2000

0.25

The correlation between INCY and INSM shifts across timeframes, from 0.24 (3 years) to 0.37 (10 years), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap

INCY:

$20.27B

INSM:

$22.38B

EPS

INCY:

$7.06

INSM:

-$5.71

PS Ratio

INCY:

3.71

INSM:

26.29

PB Ratio

INCY:

3.60

INSM:

31.75

Total Revenue (TTM)

INCY:

$5.36B

INSM:

$819.56M

Gross Profit (TTM)

INCY:

$3.76B

INSM:

$668.55M

EBITDA (TTM)

INCY:

$1.80B

INSM:

-$1.14B

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Return for Risk

INCY vs. INSM — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

INCY
INCY Risk / Return Rank: 7777
Overall Rank
INCY Sharpe Ratio Rank: 7979
Sharpe Ratio Rank
INCY Sortino Ratio Rank: 7777
Sortino Ratio Rank
INCY Omega Ratio Rank: 7575
Omega Ratio Rank
INCY Calmar Ratio Rank: 7979
Calmar Ratio Rank
INCY Martin Ratio Rank: 7777
Martin Ratio Rank

INSM
INSM Risk / Return Rank: 6262
Overall Rank
INSM Sharpe Ratio Rank: 6565
Sharpe Ratio Rank
INSM Sortino Ratio Rank: 6262
Sortino Ratio Rank
INSM Omega Ratio Rank: 6868
Omega Ratio Rank
INSM Calmar Ratio Rank: 5858
Calmar Ratio Rank
INSM Martin Ratio Rank: 5959
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

INCY vs. INSM - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Incyte Corporation (INCY) and Insmed Incorporated (INSM). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.


INCYINSMDifference
Sharpe ratioReturn per unit of total volatility

+0.68

Sortino ratioReturn per unit of downside risk

+0.74

Omega ratioGain probability vs. loss probability

1.26

1.22

+0.05

Calmar ratioReturn relative to maximum drawdown

2.52

0.81

+1.71

Martin ratioReturn relative to average drawdown

5.66

1.93

+3.73

INCY vs. INSM - Sharpe Ratio Comparison

The current INCY Sharpe Ratio is 1.41, which is higher than the INSM Sharpe Ratio of 0.73. The chart below compares the historical Sharpe Ratios of INCY and INSM, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.


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Sharpe Ratios by Period


INCYINSMDifference

Sharpe Ratio (1Y)

Calculated over the trailing 1-year period

1.41

0.73

+0.68

Sharpe Ratio (5Y)

Calculated over the trailing 5-year period

0.11

0.45

-0.34

Sharpe Ratio (10Y)

Calculated over the trailing 10-year period

0.04

0.31

-0.27

Sharpe Ratio (All Time)

Calculated using the full available price history

0.21

-0.02

+0.23

Drawdowns

INCY vs. INSM - Drawdown Comparison

The maximum INCY drawdown since its inception was -98.54%, roughly equal to the maximum INSM drawdown of -98.65%. Use the drawdown chart below to compare losses from any high point for INCY and INSM.


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Drawdown Indicators


INCYINSMDifference

Max Drawdown

Largest peak-to-trough decline

-98.54%

-98.65%

+0.11%

Max Drawdown (1Y)

Largest decline over 1 year

-18.33%

-52.06%

+33.73%

Max Drawdown (3Y)

Largest decline over 3 years

-33.83%

-52.06%

+18.23%

Max Drawdown (5Y)

Largest decline over 5 years

-41.53%

-52.06%

+10.53%

Max Drawdown (10Y)

Largest decline over 10 years

-66.47%

-64.84%

-1.63%

Current Drawdown

Current decline from peak

-35.82%

-50.87%

+15.05%

Average Drawdown

Average peak-to-trough decline

-59.92%

-86.12%

+26.20%

Ulcer Index

Depth and duration of drawdowns from previous peaks

8.14%

21.89%

-13.75%

Volatility

INCY vs. INSM - Volatility Comparison

The current volatility for Incyte Corporation (INCY) is 8.99%, while Insmed Incorporated (INSM) has a volatility of 30.56%. This indicates that INCY experiences smaller price fluctuations and is considered to be less risky than INSM based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


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Volatility by Period


INCYINSMDifference

Volatility (1M)

Calculated over the trailing 1-month period

8.99%

30.56%

-21.57%

Volatility (6M)

Calculated over the trailing 6-month period

23.00%

43.84%

-20.84%

Volatility (1Y)

Calculated over the trailing 1-year period

32.93%

58.25%

-25.32%

Volatility (5Y)

Calculated over the trailing 5-year period, annualized

29.37%

72.66%

-43.29%

Volatility (10Y)

Calculated over the trailing 10-year period, annualized

34.27%

78.47%

-44.20%

Dividends

INCY vs. INSM - Dividend Comparison

Neither INCY nor INSM has paid dividends to shareholders.


Tickers have no history of dividend payments

Financials

INCY vs. INSM - Financials Comparison

This section allows you to compare key financial metrics between Incyte Corporation and Insmed Incorporated. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


0.00500.00M1.00B1.50B20222023202420252026
1.27B
305.96M
(INCY) Total Revenue
(INSM) Total Revenue
Values in USD except per share items

INCY vs. INSM - Profitability Comparison

The chart below illustrates the profitability comparison between Incyte Corporation and Insmed Incorporated over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

Gross Margin
Operating Margin
Net Margin
Quarterly
Annual

0.0%20.0%40.0%60.0%80.0%100.0%202220232024202520260
84.5%
Portfolio components
INCY - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Incyte Corporation reported a gross profit of 0.00 and revenue of 1.27B. Therefore, the gross margin over that period was 0.0%.

INSM - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Insmed Incorporated reported a gross profit of 258.54M and revenue of 305.96M. Therefore, the gross margin over that period was 84.5%.

INCY - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Incyte Corporation reported an operating income of 301.12M and revenue of 1.27B, resulting in an operating margin of 23.7%.

INSM - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Insmed Incorporated reported an operating income of -198.20M and revenue of 305.96M, resulting in an operating margin of -64.8%.

INCY - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Incyte Corporation reported a net income of 303.33M and revenue of 1.27B, resulting in a net margin of 23.8%.

INSM - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Insmed Incorporated reported a net income of -163.56M and revenue of 305.96M, resulting in a net margin of -53.5%.


Frequently Asked Questions


INCY and INSM have a correlation of 0.25, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

INSM has higher volatility (30.56%) compared to INCY (8.99%). In terms of maximum drawdown, INCY dropped -98.54% vs INSM's -98.65%.

INCY currently has the higher Sharpe Ratio (1.41 vs 0.73), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.

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