INCY vs. INSM
INCY (Incyte Corporation) and INSM (Insmed Incorporated) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. Over the past 10 years, INCY returned 3.00%/yr vs 24.10%/yr for INSM. Their 0.25 correlation means their historical movements had little consistent relationship.
Performance
INCY vs. INSM - Performance Comparison
Loading charts...
Returns By Period
In the year-to-date period, INCY achieves a 21.01% return, which is significantly higher than INSM's -43.35% return. Over the past 10 years, INCY has underperformed INSM with an annualized return of 3.00%, while INSM has yielded a comparatively higher 24.10% annualized return.
INCY
- 1D
- -2.82%
- 1M
- 2.28%
- 6M
- 19.44%
- YTD
- 21.01%
- 1Y
- 58.12%
- 3Y*
- 23.35%
- 5Y*
- 9.09%
- 10Y*
- 3.00%
- ALL TIME*
- 13.53%
INSM
- 1D
- -2.85%
- 1M
- -11.65%
- 6M
- -37.15%
- YTD
- -43.35%
- 1Y
- -9.28%
- 3Y*
- 64.55%
- 5Y*
- 32.00%
- 10Y*
- 24.10%
- ALL TIME*
- -1.83%
Liquidity Comparison
| Position | Avg. Volume Value (2W) | Avg. Volume Value (1M) | Avg. Volume Value (3M) |
|---|---|---|---|
| $274.43M | $232.80M | $198.80M | |
| $231.83M | $255.55M | $410.72M |
INCY vs. INSM - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
INCY Incyte Corporation | 21.01% | 43.00% | 10.00% | -21.83% | 9.43% | -15.61% | -0.39% | 37.32% | -32.86% | -5.55% |
INSM Insmed Incorporated | -43.35% | 152.09% | 122.78% | 55.11% | -26.65% | -18.17% | 39.41% | 82.01% | -57.92% | 135.68% |
Correlation
The correlation between INCY and INSM is 0.31, which is low. Their historical price movements had little consistent relationship.
| Correlation | |
|---|---|
Correlation (1Y) Focuses on recent behavior, but can change the most. | 0.31 |
Correlation (3Y) Balances recent behavior with more history. | 0.25 |
Correlation (5Y) Shows whether the relationship held over a longer period. | 0.33 |
Correlation (10Y) Provides a long-term view across more market conditions. | 0.37 |
Correlation (All Time) Calculated using the full available price history since Jun 1, 2000 | 0.25 |
The correlation between INCY and INSM shifts across timeframes, from 0.25 (all time) to 0.37 (10 years), reflecting how their relationship changes across market environments.
Fundamentals
INCY:
$24.23B
INSM:
$21.37B
INCY:
$7.85
INSM:
-$5.54
INCY:
4.22
INSM:
25.69
INCY:
3.92
INSM:
30.14
INCY:
$5.82B
INSM:
$819.56M
INCY:
$5.39B
INSM:
$668.55M
INCY:
$2.04B
INSM:
-$1.14B
Compare stocks, funds, or ETFs
Search for stocks, ETFs, and funds for a quick comparison or use the comparison tool for more options.
Return for Risk
INCY vs. INSM — Risk / Return Rank
INCY
INSM
INCY vs. INSM - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Incyte Corporation (INCY) and Insmed Incorporated (INSM). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| INCY | INSM | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +1.96 | ||
| Sortino ratioReturn per unit of downside risk | +2.40 | ||
| Omega ratioGain probability vs. loss probability | 1.32 | 1.02 | +0.30 |
| Calmar ratioReturn relative to maximum drawdown | 3.27 | -0.14 | +3.41 |
| Martin ratioReturn relative to average drawdown | 7.23 | -0.27 | +7.51 |
Loading charts...
Drawdowns
INCY vs. INSM - Drawdown Comparison
The maximum INCY drawdown since its inception was -98.54%, roughly equal to the maximum INSM drawdown of -98.65%. Use the drawdown chart below to compare losses from any high point for INCY and INSM.
Loading charts...
Drawdown Indicators
| INCY | INSM | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -98.54% | -98.65% | +0.11% |
Max Drawdown (1Y)Largest decline over 1 year | -18.33% | -56.54% | +38.21% |
Max Drawdown (3Y)Largest decline over 3 years | -33.83% | -56.54% | +22.71% |
Max Drawdown (5Y)Largest decline over 5 years | -40.50% | -56.54% | +16.04% |
Max Drawdown (10Y)Largest decline over 10 years | -66.47% | -64.84% | -1.63% |
Current DrawdownCurrent decline from peak | -21.71% | -53.36% | +31.65% |
Average DrawdownAverage peak-to-trough decline | -59.75% | -85.89% | +26.14% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 8.26% | 29.74% | -21.48% |
Volatility
INCY vs. INSM - Volatility Comparison
Incyte Corporation (INCY) has a higher volatility of 11.85% compared to Insmed Incorporated (INSM) at 10.10%. This indicates that INCY's price experiences larger fluctuations and is considered to be riskier than INSM based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
Loading charts...
Volatility by Period
| INCY | INSM | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 11.85% | 10.10% | +1.75% |
Volatility (6M)Calculated over the trailing 6-month period | 24.86% | 42.65% | -17.79% |
Volatility (1Y)Calculated over the trailing 1-year period | 33.44% | 52.55% | -19.11% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 30.10% | 72.76% | -42.66% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 34.35% | 78.39% | -44.04% |
Dividends
INCY vs. INSM - Dividend Comparison
Neither INCY nor INSM has paid dividends to shareholders.
Financials
INCY vs. INSM - Financials Comparison
This section allows you to compare key financial metrics between Incyte Corporation and Insmed Incorporated. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
INCY vs. INSM - Profitability Comparison
INCY - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Aug 2026, Incyte Corporation reported a gross profit of 1.57B and revenue of 1.67B. Therefore, the gross margin over that period was 93.7%.
INSM - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Aug 2026, Insmed Incorporated reported a gross profit of 258.54M and revenue of 305.96M. Therefore, the gross margin over that period was 84.5%.
INCY - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Aug 2026, Incyte Corporation reported an operating income of 697.90M and revenue of 1.67B, resulting in an operating margin of 41.7%.
INSM - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Aug 2026, Insmed Incorporated reported an operating income of -198.20M and revenue of 305.96M, resulting in an operating margin of -64.8%.
INCY - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Aug 2026, Incyte Corporation reported a net income of 585.61M and revenue of 1.67B, resulting in a net margin of 35.0%.
INSM - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Aug 2026, Insmed Incorporated reported a net income of -163.56M and revenue of 305.96M, resulting in a net margin of -53.5%.
Frequently Asked Questions
INCY and INSM have a correlation of 0.31, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
INCY has higher volatility (11.85%) compared to INSM (10.10%). In terms of maximum drawdown, INCY dropped -98.54% vs INSM's -98.65%.
INCY currently has the higher Sharpe Ratio (1.80 vs -0.15), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
Find the right allocation for INCY and INSM
Add both to a portfolio and optimize allocations for your target — whether that's maximizing returns, minimizing drawdowns, or balancing risk across holdings.
Open Portfolio Optimizer